Mycolicibacterium rufum: MJO55_03455
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Entry
MJO55_03455 CDS
T08167
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mrf
Mycolicibacterium rufum
Pathway
mrf00860
Porphyrin metabolism
mrf01100
Metabolic pathways
mrf01110
Biosynthesis of secondary metabolites
mrf01120
Microbial metabolism in diverse environments
mrf01240
Biosynthesis of cofactors
Module
mrf_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mrf_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mrf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MJO55_03455
Enzymes [BR:
mrf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MJO55_03455
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MJO55_03455
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ULP37508
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Position
706637..708307
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AA seq
556 aa
AA seq
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MTLRGRKGKPGRITFVGSGPGDPGLLTTRARAVLANAALVFTDPDVPEAVLALAGSELPP
PSGPVQAAGAPEAAAADAAPAETAEPVIPGGPDIRPALGDPAEVAKTLATEARTGVDVVR
LVAGDPLSIDAVITEINALARTQLTFEIVPGLPDTSAVPTYAGLPLGSSHTVADVRDPNV
DWAALAAAPGPLILHATASHLPEAARTLIEYGLAENTPAVVTANGTTCQQRSVEATLAGL
LDKAVLDKPAGVEPSGPLTGTLVVTIGRTVANRAKLNWWESRALYGWTVLVPRTKDQAGE
MSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFN
EFGLDARAFSGVKIACVGQATADRVRAFGINPELVPTGEQSSLGLLDEFPPYDDIFDPVN
RVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVCFTSS
STVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVGPLVEALAEHAARL
RAEGALPPPRKKSRRR
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgaccttgcgaggacgcaagggcaagcccggccgcatcacgttcgtcggctccgggccc
ggggatccgggcctgctgacgacgcgcgcccgcgccgtattggccaacgccgccctcgtc
ttcaccgaccccgacgtaccggaagcggtgctcgcgctggcgggttcggagctgccgccg
ccgtcgggacccgttcaggcggccggtgcccccgaggccgcggccgccgatgccgcgccc
gccgagacggccgagcccgtcatccccggcggccccgacatccggcccgcgctcggtgac
ccggccgaggtcgccaagacgttggccaccgaggcccgcaccggcgtggacgtggtccgc
ctcgtcgccggtgacccgctgtcgatcgacgcggtgatcaccgagatcaacgcgctggca
cgcacgcagctgaccttcgagatcgtcccgggtctgccggacacgtcggcggtgccgacc
tacgcgggcctgccgctggggtcgtcgcacaccgtcgccgacgtccgcgaccccaacgtc
gactgggccgcgctggccgccgcgcccggaccgctgatcctgcacgcgaccgcctcgcat
ctgcccgaggccgcgcgcacgctgatcgagtacgggctcgccgagaacacgcccgccgtc
gtcaccgccaacggcaccacgtgccagcagcgttcggtggaggccacgcttgcgggcctg
ctggacaaggcggtgctggacaagcccgccggtgtcgagccgtccggcccgctgaccggc
acgctggtcgtgaccatcggccggaccgtggccaaccgcgccaagctgaactggtgggag
agccgggcactgtacggctggaccgtgctggtgccccgcaccaaggaccaggcgggcgag
atgagcgaccggctcgtcggccacggcgcgctgcccatcgaggtgccgaccatcgcggtc
gagccgccgcgcagcccggcccagatggaaagggccgtcaagggtctggtcgacgggcgc
ttccagtgggtggtcttcacctccaccaacgcggtgcgtgcggtgtgggagaagttcaac
gagttcgggctcgacgcccgcgcgttctccggggtgaagatcgcctgcgtcgggcaggcc
accgctgaccgggtgcgtgcgttcggcatcaacccggagctggtgcccaccggcgagcag
tcctccctcggtctgctcgacgagttcccgccgtacgacgacatcttcgatccggtgaac
cgggtgctgctgccgcgcgccgacatcgccaccgagacgctggccgagggcctgcgggag
cggggctgggagatcgaggacgtcaccgcctaccggaccgtgcgggcggccccgccgccg
gcgcacacccgcgagatgatcaagaccggcggcttcgacgcggtgtgcttcacgtcgagc
tccacggtgcgcaacctcgtcggcatcgccggcaagccgcacgcccgcacgatcgtggcg
tgcatcgggccgaaaaccgctgaaaccgcagccgaattcgggctgcgcgtcgacgtccag
cccgaggtcgccgcggtcggaccgctcgtcgaggcgctcgccgagcatgccgcccggctg
cgtgccgagggcgccctgcccccgccgcggaagaagagccgccgccgctga
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