Mycobacterium saskatchewanense: MSAS_53320
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Entry
MSAS_53320 CDS
T07413
Symbol
leuC_2
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
msak
Mycobacterium saskatchewanense
Pathway
msak00290
Valine, leucine and isoleucine biosynthesis
msak00660
C5-Branched dibasic acid metabolism
msak01100
Metabolic pathways
msak01110
Biosynthesis of secondary metabolites
msak01210
2-Oxocarboxylic acid metabolism
msak01230
Biosynthesis of amino acids
Module
msak_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
msak00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MSAS_53320 (leuC_2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MSAS_53320 (leuC_2)
Enzymes [BR:
msak01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MSAS_53320 (leuC_2)
4.2.1.35 (R)-2-methylmalate dehydratase
MSAS_53320 (leuC_2)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BBX66158
UniProt:
A0A1X2C4V3
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All DBs
Position
5630308..5631756
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AA seq
482 aa
AA seq
DB search
MGSDTTGAGKPRTLAEKVWSDHVVASGGGSEQGGAPDLIYIDLHLVHEVTSPQAFDGLRL
AGRPVRRPDLTLATEDHNVPTVDIDKPIADPVSRTQVETLRHNCAEFGIRLYPMGDIEQG
IVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTM
AVNVEGRLPAGVTAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEA
GARAGMVAPDETTYEYLRGRPHAPTGAQWDEAMAYWQQLRTDDGAEFDTDVYLDATELSP
FVTWGTNPGQGVPLSAAVPDPELIADDGERQAAEKALAYMDLRPGTPMREVGVDAVFVGS
CTNGRIEDLRAVADVLRGRKVAPGVRMLVVPGSMRVRAQAEAEGLGEIFTAAGAEWRQAG
CSMCLGMNPDQLAPGERCAATSNRNFEGRQGKGSRTHLVSPVVAAATAVRGKLSAPADLN
SH
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgggatccgacaccacgggggccggcaagccgcgcacgctggccgaaaaggtatggagc
gaccacgttgtggcatccggcggcggttccgagcagggcggtgctcccgacctcatctac
atcgacctgcacctggtgcatgaggtcaccagcccgcaggccttcgacggcctccgcctg
gccggtcgaccggtgcggcggcccgacctgacgctggccaccgaggatcacaacgtgccc
accgtcgacatcgacaagccgatcgctgacccggtctcacgcactcaggtcgaaacgttg
cgacacaactgcgccgaattcggcatccggctctacccgatgggtgacatcgagcagggc
atcgtccacgtggtgggaccgcagttggggctgacgcagccgggaatgacgatcgtgtgt
ggggatagtcacacgtcgacgcatggagcattcggtgcgctcgccatgggaattggtacc
tcggaggtcgagcatgtcctggccacgcagacattgccgctgcggccgttcaagacgatg
gcggtcaatgtcgagggtcgcctgcccgccggcgtgacggccaaagacatcattctggcg
ttgatcgccaagatcggcaccggcggcgggcagggccacgtcatcgaataccggggcagt
gccatcgaatcactgtccatggaaggccggatgaccatctgcaatatgagcatcgaggcc
ggcgcgcgcgcgggcatggtggctcccgacgagaccacttacgaatatctgcggggtcgt
ccgcacgcaccgacgggtgcccagtgggacgaggccatggcctactggcaacagctacgc
accgatgacggcgcggaattcgacaccgacgtctacctcgacgcaaccgagttgagcccg
ttcgtcacgtggggaaccaacccgggccagggggtgccgttgtcggcggcggttccggac
cccgagctgatcgccgacgacggcgagcgtcaggccgccgagaaagccttggcctacatg
gaccttcggcccggaacaccgatgcgcgaggtcggcgtcgacgccgtgtttgtcgggtct
tgtaccaacggtcgtatcgaggatctgcgcgcggtggccgacgtgttgcgcggccgcaag
gtggcccccggggtgcggatgctcgtcgtcccgggttccatgcgcgtgcgcgcccaggcc
gaagccgaagggctgggtgagattttcaccgccgccggtgccgaatggcggcaggcgggc
tgttcgatgtgcctgggcatgaaccccgaccagcttgcgcccggcgagcgatgcgccgcg
acgtccaaccgcaacttcgaagggcggcagggcaaaggcagccgtacgcacctcgtgtca
ccggtcgtcgccgccgcgacggcggtccgtggaaaactctccgccccggccgacttgaac
tcacactga
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