Mycobacterium stomatepiae: MSTO_31310
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Entry
MSTO_31310 CDS
T07145
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
msto
Mycobacterium stomatepiae
Pathway
msto00860
Porphyrin metabolism
msto01100
Metabolic pathways
msto01110
Biosynthesis of secondary metabolites
msto01120
Microbial metabolism in diverse environments
msto01240
Biosynthesis of cofactors
Module
msto_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
msto_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
msto00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MSTO_31310 (hemD)
Enzymes [BR:
msto01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MSTO_31310 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MSTO_31310 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBY22926
UniProt:
A0A7I7QA54
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Position
complement(3184079..3185653)
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AA seq
524 aa
AA seq
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MLANAALVFTAPDVPEPVLALIGKDLPPVSGPAPAEPPPATNDGSADADPPPAASTVLSG
GADIRPALGEPAEVAKTLTAEARTGVDVVRLVSGDPLTLDAVISEVNAVARTHLHVEIVP
GLAATSAVPTYAGLPLGSSHTVADVRDPHVDWEALAAAPGPLILQATPTHLADAARTLIE
HELAETTPCVVTAQGTTCQQRSIETTLHGLTDAAVVAGAGDPVGPLTGPLVVTIGKTVNS
RSKLNWWESRALYGWTVLVPRTKDQAGEMSERLTSYGALPVEVPTIAVEPPRSPAQMERA
VKGLVDGRFQWVVFTSTNAVRAVWEKFGEFGLDARAFSGVKIACVGESTADRVRAFGISP
ELVPAGEQSSLGLLDDFPPYDSIFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYR
TVRAAPPPATTREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIIACIGPKTAETAAE
FGLRVDVQPETAAIGPLVDALAEHAARLRAEGALPPPRKKSRRR
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
gtgctggcgaatgcggccctggtgttcaccgcccccgacgtacccgaaccggtgctggcg
ctgatcggcaaggacctgccacccgtttcgggcccggcacctgccgaaccaccacccgcg
acgaacgatggctcagccgacgcggatccgcctccggcggcatccacggtgctgtccggt
ggcgccgacatccgcccggcgctgggtgagcccgccgaggtcgccaagacgctgaccgcc
gaggcccgcacgggtgtcgacgtggtgcggctggtgtccggtgacccgctgaccctcgac
gcggtgatcagcgaggtgaacgccgtcgcgcgcacacacctgcatgtcgagatcgtgccg
ggtctggccgcgaccagcgcggtgcccacatatgcgggactgccgctgggctcgtcgcac
acggtggccgacgtgcgcgacccacatgtggactgggaagctttggcggcggctcccgga
cccctgatcctgcaggccaccccgacacacctggccgacgcggcgcgcacgttgatcgag
cacgagctggcggagaccactccgtgtgtggtgaccgcgcagggcaccacctgtcagcag
cgttcgatcgaaaccacgctgcacgggctgaccgacgccgccgtcgtggccggcgccggc
gaccccgtgggtccgttgaccggaccgctggtggtgaccatcggcaagacggtgaacagc
cggtcgaagctgaactggtgggagagccgcgccctgtacggctggaccgtcctggtgccg
cgcaccaaggaccaggccggcgagatgagtgagcggctgacgtcgtacggcgcgttgccg
gtcgaggtgccgaccatcgccgtcgagccgccgcgcagccccgcccagatggagcgcgcc
gtcaaaggattggtcgacgggcggttccagtgggtggtgtttacctccaccaatgcggtc
cgtgcggtgtgggagaagttcggcgagttcgggctggacgcccgagcgttctccggcgtg
aagatcgcctgcgtcggcgagtcgacggccgaccgggtccgcgcattcgggatcagcccc
gagctggtgccggccggggagcagtcctcgctgggcctgctggacgactttccgccctac
gacagcatttttgatccggtgaaccgggtcctgctgccgcgtgccgacattgccaccgag
acgctggccgaaggtctgcgcgaacgcggttgggagatcgaggatgtcaccgcgtaccgg
acggtgcgcgcagcaccgccgccggcgaccacccgcgaaatgatcaagacgggcggcttc
gacgcggtgtgcttcacctccagctcgacggtgcgcaacctggtcggcatcgccggtaaa
ccccacgcgcgcaccatcattgcctgcatcggccccaagacggccgagaccgccgccgag
ttcggcctgcgggtggatgtgcagcccgaaaccgctgcgatcggtccactggtcgacgcg
ctggccgaacacgccgcgcggttgcgcgccgagggtgcgctgccaccgccgcgcaagaag
agccgcaggcgctag
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