Methanothermobacter thermautotrophicus: MTH_1386
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Entry
MTH_1386 CDS
T00009
Name
(GenBank) 3-isopropylmalate dehydratase, LeuD subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mth
Methanothermobacter thermautotrophicus
Pathway
mth00290
Valine, leucine and isoleucine biosynthesis
mth00660
C5-Branched dibasic acid metabolism
mth01100
Metabolic pathways
mth01110
Biosynthesis of secondary metabolites
mth01210
2-Oxocarboxylic acid metabolism
mth01230
Biosynthesis of amino acids
Module
mth_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mth_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
mth00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MTH_1386
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MTH_1386
Enzymes [BR:
mth01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MTH_1386
4.2.1.35 (R)-2-methylmalate dehydratase
MTH_1386
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AAB85863
UniProt:
O27439
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All DBs
Position
1253910..1255169
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AA seq
419 aa
AA seq
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MSMTVSEKILARASGKDRVEAGEIVMADIDVAMTHDLTGPLSVESFRAIGEDRVWDPEKI
VVIFDHQVPADSIEAAQNHMIMRDFVEEQGIRNFYDVREGVCHQVLPEKGHVVPGEVVVG
TDSHTCTHGALGAFATGIGSTDMAMVFATGKLWFRVPETLRFDVRGKLREHVYAKDVILN
IIGRVGADGATYMACEFAGETVAEMSVSDRMVLSNMAIEMGGKTGIVEPDEKTLNYVRRR
SGKPWRVFKTDPDAPSLSVMEVDVSDLEPQVACPHNVDNVKPVTEVEGTEIDQVFLGSCT
NGRLSDLRDAAAILKNRKVSDSVRMLVIPASREVYRRALDEGLIEIFVDAGALVCNPCCG
PCLGGHVGLVGPGEVSLSTSNRNFRGRQGSPEAEVYLSSAAVAAASAVKGSITHPGSLK
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atgtctatgactgtttctgagaagatacttgccagggcttcaggtaaggatagggtggaa
gccggtgaaatagttatggcggatatagatgttgcgatgacccatgacctcacaggtccc
ctgtcggttgagtccttcagggccataggtgaggatagggtctgggaccctgaaaaaatc
gttgtgatattcgatcaccaggtccctgcagactccattgaagccgcccagaaccacatg
ataatgagggacttcgtagaggagcagggaatacggaacttctatgacgttcgtgaaggc
gtctgtcaccaggtgctccctgagaagggccatgttgtgcccggtgaggtcgtggtgggt
acagactcccacacctgcacccacggggccctcggagccttcgcaacgggtataggttca
acagatatggccatggtatttgcaactgggaaactttggttcagggtccctgaaaccctg
agatttgatgtgaggggaaaactcagggagcacgtctatgcaaaggacgtcatactgaac
ataatagggagggttggtgccgatggcgcaacctacatggcctgtgaatttgcaggtgaa
accgttgcagaaatgagtgtatccgaccgtatggtcctctcaaatatggcaatagagatg
ggtggtaagacaggaatcgtggaacctgacgaaaaaaccctgaactatgtcaggaggagg
tcaggtaaaccctggagggtcttcaaaacagaccctgacgctccatccctcagtgtcatg
gaggtcgacgtgagtgaccttgaaccccaggtcgcctgtccacacaatgtggacaatgtg
aaacccgtcaccgaggtggaggggacagagatagaccaggtcttccttggttcatgcaca
aatggaaggctcagtgacctcagggacgctgccgccatactgaagaacaggaaggtctca
gacagtgtcaggatgctcgtcatacctgcctccagggaggtctaccgcagggcccttgac
gagggactgattgagatattcgtggatgcaggagccctggtatgcaacccctgctgcggc
ccctgcctcggaggacacgttggactggtcggaccaggggaggtgagcctctcaacctca
aacaggaacttcagggggaggcagggaagccccgaagcagaggtctacctctcctcagca
gccgtggcagccgcatctgcagtgaagggcagcataacccaccctgggagtctgaagtag
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