Macaca thibetana thibetana (Pere David's macaque): 126946404
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Entry
126946404 CDS
T08579
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00010
Glycolysis / Gluconeogenesis
mthb00020
Citrate cycle (TCA cycle)
mthb00620
Pyruvate metabolism
mthb00785
Lipoic acid metabolism
mthb01100
Metabolic pathways
mthb01200
Carbon metabolism
mthb01210
2-Oxocarboxylic acid metabolism
mthb04066
HIF-1 signaling pathway
mthb04922
Glucagon signaling pathway
mthb05230
Central carbon metabolism in cancer
mthb05415
Diabetic cardiomyopathy
Module
mthb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
126946404
00020 Citrate cycle (TCA cycle)
126946404
00620 Pyruvate metabolism
126946404
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
126946404
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
126946404
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
126946404
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
126946404
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
126946404
Enzymes [BR:
mthb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
126946404
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
126946404
NCBI-ProteinID:
XP_050632598
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All DBs
Position
X:18439673..19003235
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAATYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcagaagccggca
agcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaagcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcctaccgggct
catggctttaccttcacccggggcctttccgtccgagaaattctcgcagagcttacagga
cgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgccaagaacttc
tacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggattgctctagcc
tgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggtgctgctaac
cagggccagatatttgaagcttacaacatggcagctttgtggaaattaccttgtattttc
atctgtgagaataatcgctatggaatgggaacatctgttgagagagcagcagccagcact
gattactacaagagaggcgatttcattcctgggctgagagtggatggaatggatatcttg
tgcgtccgagaggcgacaaggtttgctgccacctattgtagatctgggaaggggcccatc
ctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaaattgatgtg
gaagtgaggaaggagattgaggatgctgcccagtttgccacggccgatcctgagccacct
ttggaggagctgggctaccacatctactccagcgacccacctttcgaagttcgtggtgcc
aatcagtggatcaagtttaagtcagtcagttaa
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