Micromonospora tulbaghiae: CSH63_29135
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Entry
CSH63_29135 CDS
T05651
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mtua
Micromonospora tulbaghiae
Pathway
mtua00860
Porphyrin metabolism
mtua01100
Metabolic pathways
mtua01110
Biosynthesis of secondary metabolites
mtua01120
Microbial metabolism in diverse environments
mtua01240
Biosynthesis of cofactors
Module
mtua_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mtua_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mtua00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CSH63_29135
Enzymes [BR:
mtua01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CSH63_29135
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CSH63_29135
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AYF31439
UniProt:
A0A1C4XJI7
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All DBs
Position
6238891..6240471
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AA seq
526 aa
AA seq
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MTRTRKPVGQIAFVGAGPGDPGLLTRRALDALVDADQVVYDRGVPESLLAHVRAQARPDA
EFSPAEGVPGDVAKVLISAARAGQNAVHLVAGDPFGHDSVVKEVQAVARTAAHFEVVPGV
GQAEGVATYAGVPLPGVRTAADVEDVTALDFEALATAVGRGSLALAVDAGDLAAVRDGLL
AAGVDGTTAVGVTGDGTGETQYTTTSSVDSFVAAALGFTGRVVLTVGAAVTDRDKLSWWE
NRPLYGWKVLVPRTKEQAGVMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGDATAEAVRAFGIQPELIPSGEQ
SSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLTERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVDVQ
PPHASVPDLVEALAAYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcacccgtaagcccgtaggccagatcgcattcgtcggggccggtcccggcgac
ccgggcctgctgacccgccgggcgctggacgccctggtcgacgccgaccaggtggtctac
gaccggggcgtacccgagtcgctcctggcgcacgtccgcgcccaggcccggcccgacgcc
gagttcagccccgccgagggcgtaccgggggacgtggcgaaggtgctgatctccgcggcc
cgggccgggcagaacgccgtgcacctggtcgccggtgacccgttcggccacgactcggtg
gtcaaggaggtgcaggcggtcgcccgtaccgccgcgcacttcgaggtggtgccgggcgtc
ggccaggccgagggcgtcgccacctacgcgggtgtcccgctgccgggcgtacgcaccgcc
gccgacgtcgaggacgtcaccgcgctggacttcgaggcgctcgccacggccgtgggccgg
ggttcgctggcgctcgcggtggacgccggtgacctggccgccgtccgggacggcctgctg
gccgccggggtcgacggcaccacagcggtcggggtgaccggcgacggcaccggcgagacg
cagtacaccaccacgtcgagcgtggactcgttcgtcgcggcggcgctcggcttcaccggc
cgggtggtgctcaccgtcggcgcggccgtcaccgaccgcgacaagctgagctggtgggag
aaccgcccgctgtacggctggaaggtgctggtgccccgcaccaaggagcaggcgggcgtg
atgagcgcacggctgcgcgcctacggggcgatcccgtgcgaggtgccgaccatcgcggtc
gagccgccgcgcaccccggcgcagatggagcgggcggtcaagggcctggtcgacggccgg
tacgcctgggtcatcttcacctcggtgaacgcggtccgggcggtgtgggagaagttcgcc
gagcacggcctcgacgcccgccacttcggcggcgtgaagatcgcctgcatcggtgacgcc
accgccgaggcggtccgcgccttcggcatccagcccgagctgatcccgtccggggagcag
tcctccgagggcctgctggccgagttctcgccgcacgacgagatcctcgacccggtcggc
cgggtgctgctgccgcgcgccgacattgccaccgagaccctggccgccggcctgaccgag
cggggctgggaggtcgacgacgtgaccgcgtaccggaccgtgcgcgcggcgccgccgccc
gccgagatccgcgacgcgatcaagtcgggcgggttcgacgcggtgctgttcacctcgtcg
tccacggtgcggaacctcgtcggtatcgccgggaagccgcacgcgcggaccgttgttgca
gtgatcgggcccaagacggcggagaccgcgaccgagttcggcctgcgcgtcgacgtgcag
ccgccgcacgcctcggtccccgacctggtggaggcgctcgccgcctacgccgtcgagctg
cgggagaagctcgccgccatgccggcgaagcagcgccggggctcgaaggtgcagggcccg
accgccctgcggttccgctga
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