Mycobacterium tuberculosis BT1: HKBT1_1263
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Entry
HKBT1_1263 CDS
T03152
Symbol
rocA
Name
(GenBank) delta-1-pyrroline-5-carboxylate dehydrogenase
KO
K00294
1-pyrroline-5-carboxylate dehydrogenase [EC:
1.2.1.88
]
Organism
mtut
Mycobacterium tuberculosis BT1
Pathway
mtut00250
Alanine, aspartate and glutamate metabolism
mtut00330
Arginine and proline metabolism
mtut01100
Metabolic pathways
Module
mtut_M00970
Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:
mtut00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
HKBT1_1263 (rocA)
00330 Arginine and proline metabolism
HKBT1_1263 (rocA)
Enzymes [BR:
mtut01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
HKBT1_1263 (rocA)
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
AHJ50209
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All DBs
Position
1328312..1329955
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AA seq
547 aa
AA seq
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MLAGMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGE
RIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAG
PWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDY
RPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPG
VINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGG
KDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRY
GDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDD
PTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLR
FAAGNFYVNDKPTGAVVGRQPFGGARGSGTNDKAGSPLNLLRWTSARSIKETFVAATDHI
YPHMAVD
NT seq
1644 nt
NT seq
+upstream
nt +downstream
nt
atgctggcaggcatggacgcgatcacccaggtgccggttccggccaacgagccggtgcac
gactatgcgccgaaatccccggaacggacccggctgcgcaccgaactggcctccctggcc
gatcaccccatcgacctgccgcacgtcatcggcggccgacaccggatgggcgacggcgag
cgaatcgacgtcgtgcagccgcaccggcacgccgccaggctgggcaccctgaccaacgcc
acccacgccgacgccgcggccgccgtcgaagccgccatgtctgccaaaagtgactgggcg
gcactgccgttcgatgaacgtgccgcggtgttcctgcgcgccgccgatctgttggccggg
ccgtggcgggaaaagatcgccgccgcaaccatgctcggccaatccaagtcggtgtaccag
gccgagatcgacgcggtctgcgagctgatcgacttctggcggttcaacgtcgctttcgcc
cgacagattttggagcagcagccgatcagtggcccgggggaatggaaccggatcgactac
cgcccgctggacggtttcgtctacgcgatcacgccgttcaacttcacctcgatcgccggc
aatctgccgaccgccccggctctgatgggcaacaccgtgatctggaagccgtcgatcacc
cagacgctggcggcctatctgaccatgcaactgctcgaggccgccgggttgccgcccggg
gtgatcaacctggtcactggcgacggattcgcggtttccgatgtggcactggccgatcca
cggctggccggcatccacttcaccgggtcgacggctaccttcggccacctatggcagtgg
gtgggtaccaatatcggccgctaccatagctatccgcgactggtcggcgagaccgggggc
aaggacttcgtggtggcgcacgcctcggcccgcccggatgtgctgcgcacggccctgatt
cgcggagcattcgattaccagggccagaagtgctcggcggtgtcgcgagcgtttatcgcg
cattcggtgtggcagcggatgggcgatgagttgctggccaaagccgccgagctgcgctac
ggtgacatcaccgacctgtccaactacggtggtgcgctgatcgaccagcgcgccttcgtc
aagaacgtcgacgccatcgaacgggccaaaggcgcggccgcggtcaccgtcgccgtcggc
ggcgaatacgacgacagcgaaggctatttcgtgcgccccacggtgttgctctccgacgac
ccgaccgacgagtcgtttgtcatcgagtacttcggtccgctgctgtcggtgcatgtctac
cccgacgagcgctacgagcagatcctcgacgtcatcgacaccggatcccgctacgcgctg
accggcgcggtcatcgccgacgaccggcaggccgtgctgaccgcgctggatcggctgcgg
ttcgcggcggggaacttctatgtcaacgacaagccgacgggggcggtggtggggcgtcag
ccgttcggcggtgcacgcggatcgggcaccaacgacaaggccggttcgccgttgaacctg
ctgcggtggacgtcggcgcgcagcatcaaggagacgttcgtcgcggccaccgaccacatc
tacccgcacatggcggtcgactga
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