Meriones unguiculatus (Mongolian gerbil): 110540250
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Entry
110540250 CDS
T05884
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mun
Meriones unguiculatus (Mongolian gerbil)
Pathway
mun00010
Glycolysis / Gluconeogenesis
mun00020
Citrate cycle (TCA cycle)
mun00620
Pyruvate metabolism
mun00785
Lipoic acid metabolism
mun01100
Metabolic pathways
mun01200
Carbon metabolism
mun01210
2-Oxocarboxylic acid metabolism
mun04066
HIF-1 signaling pathway
mun04922
Glucagon signaling pathway
mun05230
Central carbon metabolism in cancer
mun05415
Diabetic cardiomyopathy
Module
mun_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mun00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110540250 (Pdha1)
00020 Citrate cycle (TCA cycle)
110540250 (Pdha1)
00620 Pyruvate metabolism
110540250 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110540250 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110540250 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110540250 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110540250 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110540250 (Pdha1)
Enzymes [BR:
mun01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110540250 (Pdha1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
110540250
NCBI-ProteinID:
XP_021482728
LinkDB
All DBs
Position
X:140604457..140619992
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGTSQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgcttgctgctgtgtcccgcgtgttggcaggcacttcgcagaagccggca
agcagagtgctagtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccggtaaccacagtgctcaccagagaggat
gggctgaagtactacaggatgatgcagactgtgcgccgaatggagctaaaggcggatcag
ctgtataagcagaaaattattcgtggtttctgtcacttgtgtgatggccaggaagcctgc
tgtgttggcctagaggctggcataaaccccacggaccatctcatcacagcctatcgagct
catggcttcaccttcacccggggcctgccagtccgggcaattcttgcagagctgacagga
cgaagaggaggctgtgctaaagggaaaggcggatcaatgcacatgtatgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgccgctgggagcaggaattgctctggcc
tgtaagtacaatggaaaagatgaggtctgtttgacattatatggcgatggcgctgctaat
cagggtcaaatatttgaagcttacaatatggccgcactgtggaaattaccttgtattttc
atctgcgagaataaccgctatggcatgggtacatctgttgagagagcagcagccagtacg
gattactacaaaagaggagatttcattcctggactgagggtagatggaatggatatcttg
tgtgtccgagaagcaacaaagtttgcagctgcctactgtaggtctggtaaggggcccatc
ttaatggagctacagacttatcgttaccatggacatagtatgagtgaccctggagtcagt
taccgcactcgagaagaaatccaggaagtaagaagtaagagcgaccctatcatgcttctc
aaggatagaatggtgaacagcaatctcgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaattgaggatgctgcccagtttgccaccgctgatccagagccaccc
ttggaggagctaggctatcacatctacagcagcgaccctccctttgaagtgcgtggtgcc
aatcaatggatcaagtttaagtcagtcagttaa
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