Mycolicibacterium vanbaalenii: Mvan_0846
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Entry
Mvan_0846 CDS
T00449
Name
(GenBank) uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mva
Mycolicibacterium vanbaalenii
Pathway
mva00860
Porphyrin metabolism
mva01100
Metabolic pathways
mva01110
Biosynthesis of secondary metabolites
mva01120
Microbial metabolism in diverse environments
mva01240
Biosynthesis of cofactors
Module
mva_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mva_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mva00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Mvan_0846
Enzymes [BR:
mva01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Mvan_0846
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Mvan_0846
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ABM11684
UniProt:
A1T3D4
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Position
880655..882370
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AA seq
571 aa
AA seq
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MSLRGRKGKPGRITFVGSGPGDPGLLTTRARAVLAHAALVFTDPDVPEAVLELVGSELPP
PSGPLPPVAAGAAPKPADAVVKQDADAAEKPAEGSKAAEDAVIPGGPDVRPALGDPVEVA
KTLATEARTGVDVVRLVAGDPLSIDSVITEINALAKTQLNFEIVPGLPGTSAVPTYAGLP
LGSSHTVADVRDPNVDWAALAAAPGPLILHATASHLPEAARTLIEYGLADSTPAVVTANG
TTCQQRSIETTLGGLLDKAVLDKPAVAEPAGPLTGTLVVTLGRTVAHRAKLNWWESRALY
GWTVLVPRTKDQAGEMSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVV
FTSTNAVRAVWEKFNEFGLDARAFSGVKIACVGQATAERVRAFGINPELVPTGEQSSLGL
LDEFPPYDDIFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAQTRE
MIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAA
VGPLVEALAEHAARLRAEGALPPPRKKSRRR
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
atgagcttgcgaggacgcaagggcaagcccggccgcatcacgttcgtcggctccgggccc
ggggatccgggtctgctgacgacgcgggcgcgggcggtgttggcccacgccgccctggtg
ttcaccgatcccgacgtgcctgaagcggtgctggagctggtgggttccgagctaccgccg
ccgtcggggccgctgccgcctgtcgccgccggcgcggctccgaaacccgccgatgcggtg
gtgaaacaggacgccgacgcggcggagaagccggccgagggcagcaaggctgccgaagac
gcggtcatccccgggggacccgacgtgcgtcccgccctgggcgatccggtcgaggtcgcc
aagacgctggccaccgaggcccgcaccggggtcgacgtggtccggctcgtcgcaggagat
ccgctgtcgatcgactcggtgatcaccgagatcaacgcactggccaagacccagctgaac
ttcgagatcgtgccgggactgcccggtacctcggcggtgcccacctacgcgggtctgccg
ctgggctcgtcgcacaccgtcgcggacgtgcgcgatcccaatgtcgactgggcggcgctg
gccgccgcaccgggaccgctgatcctgcacgccacggcatcgcacctgccggaggcggca
cgcacgctgatcgagtacggcctcgccgattccaccccggccgtggtcacggccaacggc
accacctgtcagcagcgttcgatcgagacgacccttggtgggctgctcgacaaggcggtg
ctggacaagccggctgtcgccgaacccgcaggcccgctgaccggcacgctggtggtcacc
ctcggtcgcaccgtcgcccaccgcgcgaagctgaactggtgggagagcagggcactgtac
gggtggaccgttctggtgccgcgcaccaaggatcaggcgggtgagatgagcgaccgcctt
gtcggacacggcgcgctgcccatcgaggtgccgaccatcgcggtcgagccgccgcgcagc
ccggcccagatggaaagggccgtcaagggattggtggacggccggttccagtgggtggtg
ttcacctccaccaatgccgtgcgtgcggtgtgggagaagttcaacgaattcggtctggac
gcgcgcgcattctccggcgtgaagatcgcctgcgtcggtcaggcgacggcggaacgggtt
cgcgccttcgggatcaaccccgagctggtacccacgggtgaacagtcgtctctgggcctg
ctcgacgagttcccgccgtatgacgacattttcgatccggtgaaccgggtgctgttgccg
cgcgcggacatcgccaccgaaacgctggccgaaggtctgcgcgagcgcggctgggagatc
gaggacgtcaccgcctaccgcacggtgcgcgcggcaccgccgccggcgcagacccgcgag
atgatcaagaccggtggcttcgacgccgtgtgcttcacgtcgagttcgacggtgcgcaac
ttggtcggcatcgcgggtaagccgcacgcccgcaccatcgtggcctgcatcggacccaaa
accgccgagaccgcagcggagttcgggctgcgcgtggacgtgcagccggaggtcgccgcg
gtgggaccgctggtggaggcgctggccgagcacgccgccaggctgcgggccgagggtgca
ttgccgccaccgcggaagaagagccgccgccgctaa
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