Mycobacterium xenopi: MYXE_42080
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Entry
MYXE_42080 CDS
T06649
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mxe
Mycobacterium xenopi
Pathway
mxe00860
Porphyrin metabolism
mxe01100
Metabolic pathways
mxe01110
Biosynthesis of secondary metabolites
mxe01120
Microbial metabolism in diverse environments
mxe01240
Biosynthesis of cofactors
Module
mxe_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mxe00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MYXE_42080 (hemD)
Enzymes [BR:
mxe01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MYXE_42080 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MYXE_42080 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBU24418
LinkDB
All DBs
Position
complement(4229700..4231358)
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AA seq
552 aa
AA seq
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MSMRGRKPKPGRIMFVGSGPGDPGLLTTRAASVLANAALVFTDPDVPEPVQALIGTELPP
VSGAAPAGAAEVTEIADAARTETATAVVSVGPDIRPALGEPAEVAKTLIAEARSGTDVVR
LVAGDPLSVDAVITEVNAVARAHLQFEIVPGLAATAAVPTYAGLPLGSAHTIADVRGEVD
WAALAAAPGPLILQATPSHLADAARTLIDYGLAESTPCVVTAAGTTCIQRSVETTLHALT
DGVALGANDPAGPLTGPLVVTIGKTVANRAKLNWWESRPLYGWTVLVPRTKDQAGEMSER
LVSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFGL
DARAFSGVKIACVGEATADRVRAFGVSPELVPSGEQSSLGLLDEFPPYDSVFDPVNRVLL
PRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTVR
NLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAEG
ALPPPRKKSRRR
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
gtgagcatgcgagggcgcaagccgaagccgggccgcatcatgttcgtgggctccggtccc
ggcgatccgggtcttctgacgacgcgggcggccagcgtgctggccaacgccgccctggtg
ttcaccgatcccgatgtgcccgagcccgtgcaggcgctgattggcaccgaactgccgccg
gtgtcgggggcggcaccggccggcgcggccgaggtcaccgagatcgccgacgctgcgcga
accgagaccgcgacggcggtggtgtcggtcggccccgacatccggcccgcgctgggcgaa
cccgcggaagtggccaaaacgctgatcgccgaggccaggtcgggcaccgacgtggtgcgg
ctggtggccggcgatccgctgtcggtggacgcggttatcaccgaggtcaacgccgtcgcg
cgagcacatctgcaattcgagatcgtgcccgggctggccgccaccgctgcggtaccgacg
tatgcgggcctgccgttgggctcggcgcacaccattgccgacgtgcgcggcgaggtggac
tgggcggcgctggccgcggcaccgggaccgctgatcctgcaagccaccccgtcacacctg
gccgatgcggcgcgcaccctgatcgactacgggctggccgagtcgacgccgtgcgtcgtc
accgcggccggcaccacgtgcatccagcgctcggtggagaccacgctgcacgcgttgacc
gacggggtggctttgggcgccaacgaccccgcggggccgctgacagggcccttggtggtg
accatcggcaagaccgtcgccaaccgggcgaagctgaactggtgggagagccgtccgctc
tacggctggacggtgctggtgccgcggaccaaggaccaggccggggagatgagcgagcgg
ctggtgtcctacggcgcgctgccgatcgaggtgccgaccatcgccgtggagccgccgcgc
agcccggcgcaaatggaacgtgcggtcaagggtcttgtcgacggccgcttccagtgggtg
gtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcggcgagttcgggctc
gatgctcgcgcgttttccggagtgaagatcgcctgcgtcggcgaagccaccgccgatcgg
gtccgcgcgttcggggtcagccctgagctggtgccttccggcgaacagtcctcgctgggc
ctgctcgacgaattcccgccctacgacagcgttttcgacccggtgaaccgggtgctgctg
ccgcgcgccgacatcgccaccgaaaccctggctgagggtctacgcgaaagaggttgggag
atcgaagatgtcaccgcataccgtaccgttcgcgccgcgccgccaccggcggaaacccgc
gagatgatcaagaccggcggtttcgacgcggtgtgctttacgtccagctcgacggtgcgc
aaccttgtcggcattgcgggcaagccgcacgcgcgaacgatcgtcgcctgcatcggaccc
aagacggccgagacggctgccgagttcggcctgcgggtcgatgtgcagcccgagaccgcc
gcagtgggcccgctggttgacgccctggccgagcatgccgcccggctgcgcgccgagggc
gccctgccaccgccgcgcaagaagagccgcaggcgctag
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