Myotis brandtii (Brandt's bat): 102252005 Help Entry 102252005         CDS       T02920                                  Symbol INSR Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism myb  Myotis brandtii (Brandt's bat) Pathway myb04010   MAPK signaling pathway myb04014   Ras signaling pathway myb04015   Rap1 signaling pathway myb04022   cGMP-PKG signaling pathway myb04066   HIF-1 signaling pathway myb04068   FoxO signaling pathway myb04072   Phospholipase D signaling pathway myb04150   mTOR signaling pathway myb04151   PI3K-Akt signaling pathway myb04152   AMPK signaling pathway myb04211   Longevity regulating pathway myb04213   Longevity regulating pathway - multiple species myb04520   Adherens junction myb04910   Insulin signaling pathway myb04913   Ovarian steroidogenesis myb04923   Regulation of lipolysis in adipocytes myb04930   Type II diabetes mellitus myb04931   Insulin resistance myb04932   Non-alcoholic fatty liver disease myb04960   Aldosterone-regulated sodium reabsorption myb05010   Alzheimer disease myb05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:myb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102252005 (INSR)    04014 Ras signaling pathway     102252005 (INSR)    04015 Rap1 signaling pathway     102252005 (INSR)    04066 HIF-1 signaling pathway     102252005 (INSR)    04068 FoxO signaling pathway     102252005 (INSR)    04072 Phospholipase D signaling pathway     102252005 (INSR)    04022 cGMP-PKG signaling pathway     102252005 (INSR)    04151 PI3K-Akt signaling pathway     102252005 (INSR)    04152 AMPK signaling pathway     102252005 (INSR)    04150 mTOR signaling pathway     102252005 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     102252005 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102252005 (INSR)    04923 Regulation of lipolysis in adipocytes     102252005 (INSR)    04913 Ovarian steroidogenesis     102252005 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102252005 (INSR)   09149 Aging    04211 Longevity regulating pathway     102252005 (INSR)    04213 Longevity regulating pathway - multiple species     102252005 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102252005 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102252005 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102252005 (INSR)    04932 Non-alcoholic fatty liver disease     102252005 (INSR)    04931 Insulin resistance     102252005 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:myb01001]     102252005 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:myb04090]     102252005 (INSR) Enzymes [BR:myb01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102252005 (INSR) Protein kinases [BR:myb01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    102252005 (INSR) CD molecules [BR:myb04090]  Proteins   102252005 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like Motif Other DBs NCBI-GeneID:  102252005 NCBI-ProteinID:  XP_005864960 LinkDB All DBs Position Un AA seq 1384 aa AA seqDB search MYGRGFSQGQDPLSNALPPILKTHHCVLAHLSHFLHIFTLVCPSMDIRNNFTRLYELANC SIIEGHLQILLMFSSRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSR LFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNDLCYLATIDWSRILDSVEDNYIV LNKDDNEECGDVCPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTSCKSHGCTAEGL CCHPECLGSCSEPDDPTKCVACRHFYLDGRCVETCPAPYYHFRDWRCVNFSFCLDLHNKC KNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHVLEGQKIIDSVTA AQELRGCTVINGSLTINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLR LIQGDTLEVGNYSFYALDNQNLRQLWDWSKHNLTITRGKLFFHYNPKLCLSEIHKMEEIS GTKGRQERTDIALKTNGDQASCENELLKFSYIRTSSDKIMLKWEPYWPPDFRDLLGFMLF YKEAPYRNVTEFDGQDACGSNSWTVVDIDPPPRSTDPKSQAHPGWLMRSLKPWTQYAIFV KTLVTFSDERRTYGAKSDIIYIQTNATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNIT HYLVFWERQEEDSELYELDYCLKGLKLPSRTWSPPSELEGSQKHNQSEYDEAAGECCSCP KTDSQILKELEESSFRKTFENYLHNVVFVPRKISSGPGAEDSRSSRKRRALGDEGNVTTA EPTALGFPNTSTIVPTRSEEPRPFEKVVNKESLVISGLRHFTGYRIELQACNQDFPEERC SVAAYISARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKHPNGLIVLYEVSYRRYGDE ELHLCVSRRHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATYFYVTNYLDVPSNI AKIIIGPLIFVFLFSVVIGSIYLFLRKRQSDGPVGPLYASSNPEYLSASDVFPCSVYVPD EWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASMRERIEFLNE ASVMKGFACHHVVRLLGVVSKGQPTLVVMELMTHGDLKSHLRSLRPDAENNPGRPPPTLQ EMFQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGG KGLLPVRWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGY LDIPDNCPERLSELMSMCWHFNPKMRPTFLEVVDLLKDNLHPSFPEVSFFYSEENKAPEN DELEMEFEDMESVPLDRSSHCQREEDGGCPLALKRNYEDHMSYSHMNGGKKNGRVLTLPR SSPS NT seq 4155 nt NT seq  +upstreamnt  +downstreamnt atgtatggaaggggatttagccaagggcaggaccctctgagcaatgccctgccgccaatt cttaaaacccaccattgtgtgttagctcacctgtcacactttctgcatatttttactcta gtgtgtcccagcatggatatccggaacaacttcacgaggctgtatgagctggctaactgc tcgatcatcgaaggacatttgcagatactgttgatgttcagttcaaggcctgaggatttc cgagacctcagtttccccaaactcatcatgatcactgattacttgctgctgtttcgggtc tatgggctggagagcctgaaggacctgttccccaacctcacggtcatccggggctcccgc ctcttcttcaactacgcgctggtcatcttcgagatggtccacctgaaggagctgggcctc tacagcctgatgaacatcacccgggggtctgtccgcatcgagaagaacaatgatctctgc tacctggctaccatcgactggtcgcgcatcctggactcggtggaggataattacatcgtg ctgaacaaagacgacaatgaagagtgtggggacgtctgtccgggcactgcgaagggcaag accagctgccctgccactgtcatcaatgggcagtttgtcgaacggtgttggactcacagc cattgccagaaagtctgcccgaccagctgcaagtcgcacggctgcactgctgaaggcctc tgctgccaccccgagtgcctgggcagctgctctgagcccgacgaccccaccaagtgcgtg gcctgccgccacttctacctggacggtaggtgcgtggagacctgcccagccccgtactac cacttccgggactggcgctgtgtgaacttcagcttctgcctggacctgcacaacaaatgc aagaactcgcggaggcagggctgccatcagtacgtcattcacaacaacaagtgcattcct gagtgcccctctgggtacacgatgaattccagcaacttgatgtgcactccgtgtctgggc ccctgtcccaaggtctgccacgtcctggaaggtcagaagatcatcgactcagtgacagct gcccaggagcttcgaggatgcaccgtcatcaacgggagcctcaccatcaacatccgtggg ggcaacaacctggcagctgagcttgaggccaacctcggcctcattgaggaaatttcaggg tatctgaaaatccgccgttcctacgctctagtgtcactttccttcttccggaagttacgt ctgattcagggggataccttggaagttgggaactactctttctatgccttggacaaccag aacctaaggcagctatgggactggagcaaacacaacctcaccataactcgggggaaactc ttcttccactataatcccaaactctgcttgtcggaaattcacaagatggaagaaatttca ggaaccaagggacgccaggagaggaccgacattgccctgaagactaatggggaccaggcg tcctgtgaaaatgaattacttaaattttcttacatccggacatcttctgacaagatcatg ctgaaatgggagccgtactggccccctgacttccgagacctcctggggttcatgctcttc tacaaagaggccccttaccggaatgtgacggagtttgatgggcaggatgcgtgtggatcc aacagctggacggtggtggacattgacccgcctccgaggtccactgaccccaagtcacag gcccatcctgggtggctgatgcggagtctcaagccctggactcagtatgccatcttcgtg aagaccttggtcaccttttctgatgaacgccgcacatacggggccaagagcgatatcatc tatatccagacaaatgccaccaatccttccgtccccttggatcccatctcggtttctaac tcttcatcccagattatcttgaagtggaagcctccctccgaccccaacggcaacatcaca cactacctggttttctgggagaggcaggaggaagacagtgagctgtatgagctggattat tgcctcaaagggttgaagctgccctcccggacctggtccccaccatctgagttggagggt tcccagaagcacaaccagagcgagtacgacgaggctgccggcgagtgctgctcctgcccg aagactgactctcagattctgaaggaactggaggagtcctcgttcaggaagacgtttgag aattacctgcacaatgtggtcttcgtccccagaaaaatctcttcaggccctggtgctgag gacagtaggtcgtcgagaaaacgcagggcccttggtgatgaagggaacgtgacgacggct gagcccacagctctgggtttccccaacacctcaaccatcgtgcccacacgctcggaggag ccgcggcccttcgagaaagtggtgaacaaggagtcgctggtcatctcgggcctgcgccac ttcactggctaccgcatcgagctgcaggcttgcaaccaggatttccccgaggagaggtgc agtgtggcggcctacatcagcgccaggaccatgcccgaagccaaggcagatgacattgtt ggccccgtgacccatgaaatcttcgagaacaacatcgttcatttgatgtggcaggagcca aagcatccgaacggtctgattgtgctgtatgaagtgagctatcgacgatacggagatgag gagctgcacctctgtgtgtcccgcaggcacttcgccttggagcggggctgcaggctacgc gggctgtcgcccgggaattacagcgtgagagtccgggccacctccctggcgggcaatggt tcctggacagaagccacctatttctatgtgacaaactacttagacgtcccctccaatatt gcaaaaatcatcatcggccccctcatctttgtcttcctcttcagtgttgtgattggaagt atttacctattcctgaggaagaggcagtcagacgggccggtgggaccactctatgcttct tcaaaccctgagtacctcagtgccagcgatgtgttcccatgttctgtgtatgtgccggac gagtgggaggtgcctcgggagaagatcacgctcctgcgagagctggggcagggctccttc ggcatggtgtacgagggcaacgccaaggacatcatcaagggcgaggcagagactcgagtg gcggtgaagacagtcaacgagtcggccagcatgcgggagcggatcgagtttctcaacgag gcctccgtcatgaaaggcttcgcctgccatcacgtggtgcgcctcctcggggtggtgtcc aaaggccagcccacactggtggtgatggagctcatgactcacggagacctgaagagccac ctgcgttccctgcggcctgacgccgagaataaccccggccgccctcccccgaccctgcaa gagatgtttcagatggcagcggagattgctgacgggatggcatacctgaacgccaagaag tttgtgcaccgggacctcgcagctcgaaactgcatggtcgcccacgattttaccgtcaaa attggagactttggaatgaccagagacatctacgaaacggattattaccggaaaggtggc aaaggtctgcttcctgtgaggtggatggcacctgaatctttgaaggacggggtctttact gcttcttccgacatgtggtccttcggtgtggtcctgtgggaaatcaccagcttggcagaa cagccttaccaaggcctctccaatgagcaggtgctgaaattcgttatggatggagggtat ctggatatccctgacaattgtccagagagactcagtgaattgatgagcatgtgctggcat ttcaatcccaagatgaggccgaccttcctggaggtcgttgacctgctgaaggacaacctg caccccagctttccggaagtttccttcttctacagcgaggagaacaaggcacctgagaac gatgagttggagatggagtttgaggacatggagagtgtacccctggaccggtcctcacac tgtcagagggaggaggatggggggtgtccgctggccctaaagcggaattacgaggatcac atgtcctacagccacatgaatgggggcaagaaaaacggacgtgtcctgactctgccacgg tccagtccttcctaa

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