Mycolicibacterium neoaurum NRRL B-3805: MyAD_05380
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Entry
MyAD_05380 CDS
T05013
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
myn
Mycolicibacterium neoaurum NRRL B-3805
Pathway
myn00860
Porphyrin metabolism
myn01100
Metabolic pathways
myn01110
Biosynthesis of secondary metabolites
myn01120
Microbial metabolism in diverse environments
myn01240
Biosynthesis of cofactors
Module
myn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
myn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
myn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MyAD_05380
Enzymes [BR:
myn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MyAD_05380
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MyAD_05380
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
TruB_C
Motif
Other DBs
NCBI-ProteinID:
AMO04718
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Position
1142678..1144342
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AA seq
554 aa
AA seq
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MTGHAGNRGRKIRPGRITFVGSGPGDPGLLTTRARTVLANAATVFTDPDVPESVLALVGS
ELPPTSGPEPAATETPDGETVAAVVPGGPDVRPALGDPAEVAKTLAAEARNGLDVVRLVA
GDPLSVDAVIAEVNALARTQLNFEIVPGLPDTTAVPTYAGLPLGSSHTVADVRDPNVDWA
ALAAAPGPLILHATAGHLADAARTLVEYGLAENTPAVITAHGTTCQQHSVETTLVGLGDK
AILNAAEPSGGTPGPLSGPLVVTIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMS
DRLVTHGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNEF
GLDARAFSGVKIACVGQATADRVRAFGINPELVPAGEQSSLGLLDEFPPYDEIFDPVNRV
LLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVCFTSSST
VRNLVGIAGKPHARTIVACIGPKTAETAVEFGLRVDVQPETAAVGPLVEALAEHAARLRA
EGALPPPRKKSRRR
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgactgggcacgcaggtaaccggggccgcaagattcggcccggccgcatcacattcgtg
ggctccggcccaggtgatccgggcctgctgacaacgcgtgcgcggaccgtgctcgccaat
gcggcgacggtgttcaccgatcccgatgtgcccgagtcggtgctggcgctggtcggttcc
gaactgccgccgacctcgggccccgagcccgccgccaccgagacgcccgacggtgagacc
gtcgccgccgtggtgccgggtggtcccgatgtgcgaccagccctcggcgatcccgccgag
gtcgccaagacgctggccgccgaggcgcgtaacggtctcgacgtcgtccggctggtcgcc
ggtgacccgctgtcggtggacgcggtgatcgccgaggtcaatgcgctggcacggacccag
ctgaacttcgagatcgtgccgggcctgccggataccaccgcagtgccgacctatgccggt
ctgccgctgggctcgtcgcacacggtcgccgatgtgcgtgacccgaacgtcgactgggct
gcgctggccgccgcccccggaccgctgatcctgcacgcgaccgccggccacctggccgac
gccgcccgcacgctggtcgagtacggcctcgccgagaacacgccggccgtcatcaccgcg
cacggcaccacctgccagcagcattcggtggagaccacgctggtcggcctcggcgacaag
gccatcctgaacgcggccgagccctccggtggcacaccgggcccgctgtcgggtccgctg
gtcgtcacgatcggcaagacggtcgccaaccgcgcgaagctgaactggtgggagagccgg
gcgctctacggctggaccgtgctggtgccgcgcaccaaggatcaggccggcgagatgagt
gaccggctggtcacccacggcgcactgccggtcgaggtgcccaccatcgccgtcgagccg
ccgcgtagcccggcccagatggaaagggccgtcaagggtttggtggacggccggttccag
tgggtggtgttcacctccaccaacgccgtgcgtgccgtatgggagaagttcaacgagttc
ggcctggacgcccgcgcgttctcgggtgtgaagatcgcctgtgtcggccaggccaccgcc
gatcgggtgcgtgccttcggtatcaaccccgagctggtgcccgccggtgagcagtcctcg
ctgggcctgctcgacgagttcccgccgtatgacgagatcttcgacccggtgaaccgggtg
ctgctgccgcgcgccgacatcgccaccgagacgctggccgagggtctgcgtgaacgcggt
tgggagatcgaggatgtcacggcctatcgcaccgtccgtgcggccccgccgccggcgcac
acccgcgagatgatcaagaccggcgggttcgacgcggtctgcttcacctccagctcgacg
gtccgcaatctggtcggcatcgcgggtaaacctcacgcgcgcaccatcgttgcctgtatc
ggtcccaagaccgccgagacggcagtcgaattcggcctgcgcgtcgatgtgcagccggag
acggccgcggtcggtccgctggttgaggcgctcgccgagcatgccgcccggctgcgcgct
gagggtgcgctgcctccgccgcgcaagaagagccgccgccggtaa
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