Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112394989
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Entry
112394989 CDS
T08872
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi00010
Glycolysis / Gluconeogenesis
nasi00020
Citrate cycle (TCA cycle)
nasi00620
Pyruvate metabolism
nasi00785
Lipoic acid metabolism
nasi01100
Metabolic pathways
nasi01200
Carbon metabolism
nasi01210
2-Oxocarboxylic acid metabolism
nasi04066
HIF-1 signaling pathway
nasi04922
Glucagon signaling pathway
nasi05230
Central carbon metabolism in cancer
nasi05415
Diabetic cardiomyopathy
Module
nasi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
112394989 (PDHA1)
00020 Citrate cycle (TCA cycle)
112394989 (PDHA1)
00620 Pyruvate metabolism
112394989 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112394989 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
112394989 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
112394989 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112394989 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112394989 (PDHA1)
Enzymes [BR:
nasi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
112394989 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
112394989
NCBI-ProteinID:
XP_024593763
UniProt:
A0A341AVZ5
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVDVRKEIEDAAQFATADPEPP
LEELGYHIYCSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccggctggaagagggccctcctgtcactacggtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgttcgtcgaatggagttaaaagcagatcag
ctatacaaacagaaaattattcgtggtttctgtcacttgtgtgacggtcaggaagcttgt
tgtgtgggcctggaggccggcataaaccccacagaccatctgatcacagcatatcgggct
cacggctttacgtttactcgtgggctttctgtccgagcaattctcgcagagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtacgccaagaacttc
tacgggggcaatggcatcgtgggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataacgggaaagatgaaatctgtttgactttgtatggtgatggcgctgctaat
cagggtcagatattcgaagcttacaatatggcggctttgtggaaattgccttgtattttc
atctgtgagaataaccgctatgggatgggaacatctgtggagagagcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgagggtagacggaatggatatcctg
tgtgtccgggaggccacaaggtttgcagctgcctattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccatgggcacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagttagaagtaagagcgaccctatcatgcttctc
aaggataggatggtgaacagcaatctggccagtgttgaagaactaaaggaaattgatgtt
gacgtgagaaaagaaattgaggatgctgcccagtttgctacagctgaccctgaaccacct
ttggaagaactcggctatcacatctactgcagcgatccgccttttgaagtccggggtgca
aaccagtggatcaagtttaagtccatcagttaa
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