Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112396299
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Entry
112396299 CDS
T08872
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi00310
Lysine degradation
nasi01100
Metabolic pathways
nasi05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
112396299 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
112396299 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
nasi03036
]
112396299 (DOT1L)
Enzymes [BR:
nasi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
112396299 (DOT1L)
Chromosome and associated proteins [BR:
nasi03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
112396299 (DOT1L)
HMT complexes
Dot1-containing complex
112396299 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
112396299
NCBI-ProteinID:
XP_024595762
UniProt:
A0A341B2H3
LinkDB
All DBs
Position
Unknown
AA seq
1761 aa
AA seq
DB search
WLGRSLRGCAVVLPLRDSLRLWAWSGPSVTVPACFWLPPPSPQVSDECPLSSHALHSTDK
HHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLW
KGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMID
EIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWY
GKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSS
KPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSL
KNPKLREEQEAARRRQQRENKSNTTTPTKVPESKTAMPADTPMDSGAEEEKAGATTVKKP
SPSKARKKKLNKKGRKMAGRKRGRPKKMSTTNPERKPKKTQSALDLLHAQTVSRAASPSP
QGAPYQLPPSTQRRPPEQLLLAPAPPALHRLLESFKIQYLQFLAYTKTPQYKANLQQLLD
QEKEKNARLLGAVQQLFGHCQAQKEEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQ
QLREQTEQLEKGNRELRSQSLRLLKARCEELKLDWSTLSLEGLLKEKQALKSQISEKQRH
CLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGGLGRELEAEPGRPHLELDC
ARFSLPHLSNMSPELSMNGHAAGYELCGALSRPSPKQNTPQYLASPLDQEVVPCTPNHSG
RPRLEKLSGLALPDYTRLSPAKLVLRRHLSQDHTANSRATASELHSRAEHAKENGLPYQS
PGIANGIKLSPQDPRPSSPAALQMTGEKGSEKREQAGPVVCLQGLKERTYASSGEAITSL
PVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRSTPSPVPQARESSSTLEKQMGAGTHGS
GCSAAGSRSLALAPAGFAYAGSVAISGALAGSPAPLVSGAEPPTLDESSSSGSLFATVGS
RSSTPQHPPLLAQPRNCGSASPAPQLCASPRLGTQGPLPDTSKGDLPSEAGFSDPESEAK
RRIVFTISAGSSSAKQSPSSKHSPLSSGARGDGGQSHGQDSRKRGRRKRAAAGTPGFSSG
VSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPESSLKSSPVPYQDNDQ
PPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPSSARIERKIATISLESKSPPKTLENGG
GLAGRKVPASEPVNSSKWKSTFSPISDLGLAKAADSPLQAASALSHNSLFAFRPGLEEPG
AADAKLAAHPRKSFPGALPGAGGLSPSSHPASSFALGGGLAADLSLHSFSDGASLSHKAP
EAAGLGTPLSFPGPRGKEGGAADPGPFVNKRQLDGLAPKGEGGPPVCGPADKASATHGKA
GKGRDREPDVKNGHNLFMAAAAAAAAAAAAPPGGLLSGPGLAPAASSAGGTAPSVQTHRP
FLGAFAPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVSTAATRLTNSHAMGSFSS
GVAGGAVGGAFNHAVPPASAHPFGASFGSGAACRSATLSLTPLQAVASTPSSSFQAPPPA
EPRPPPPPPHLGRPPPGPPALHAPPPPNAALPPPPALLPANSEPVLLQNLASLPANQAFL
PASSAASVPPANASLSIKLASLPHKVSRPSFTVHHPPLPGLALAQAAPVIPQASSTGPPA
VWVSLGMPPPYAARLAGVKPR
NT seq
5286 nt
NT seq
+upstream
nt +downstream
nt
tggctgggcaggagcctgcgagggtgtgcagtggtccttcccctccgtgactcactgagg
ctgtgggcgtggagcggccccagcgtgactgtacccgcctgcttctggcttcctcctccg
agcccacaagtctctgatgaatgcccgctgagcagtcatgcccttcactcaactgacaaa
caccacgatgctgctcatgaaatcatcgagaccatccggtgggtctgtgaagaaatccca
gatctcaagctcgctatggagaattatgttttaatcgactacgacaccaaaagcttcgaa
agcatgcagaggctctgtgacaagtacaaccgggccatcgacagcatccaccagctgtgg
aagggcaccacgcagcccatgaagctgaacacacggccgtccacggggctcctgcgccac
atcctgcagcaggtctacaaccactcggtgaccgaccccgagaaactcaacaactatgag
cccttctccccggaggtgtacggggagacttccttcgacctggtcgcccagatgatcgac
gagatcaagatgaccgaagacgacctgtttgtggacctgggtagcggagtgggccaggtt
gtgctgcaggtcgctgcggctaccaactgcaaacatcactatggtgtcgagaaagctgac
atcccggccaagtacgcggagaccatggaccgagagttcaggaagtggatgaaatggtat
ggaaaaaagcatgcagaatacacactggagagaggagatttcctctcagaggagtggaga
gagcggatcgccaacacgagtgttatatttgtgaataactttgcctttggtcctgaggtg
gatcaccagctgaaggagcggttcgcaaacatgaaggaaggtggcagaattgtgtcctcg
aagccctttgcacctctgaacttcagaataaacagtagaaacttgagtgacatcggcacc
atcatgcgcgtcgtggagctgtcgcctctaaaaggctcggtgtcgtggacggggaagccg
gtgtcttactacctgcacaccatcgaccgcaccatacttgaaaactatttttctagtctg
aaaaatccaaaactcagggaggaacaagaggcagctcggcgccggcagcagcgggagaac
aagagcaacacgaccacccccaccaaggtgcccgagagcaagacggccatgcccgccgac
acccccatggactctggtgctgaggaagagaaagccggggcaaccactgtcaagaagcca
tctccctccaaggcccggaagaagaagctgaacaagaagggccggaagatggccggccgg
aagcgcggacgtcccaagaagatgagcaccaccaaccccgagcgcaagcccaagaagacc
cagagcgcactggacctgctgcatgcccagaccgtgtcgcgggcggcgtcgccctcgccg
cagggcgccccctatcagctacctcccagcacgcagcgacgcccccctgagcagctgctg
ctggcgcccgccccgcctgccctacaccggctgctagaatccttcaagattcagtaccta
cagttcctggcatacacaaagacccctcagtacaaggccaacctgcagcagctgctggac
caggagaaggagaagaacgcccggttgctgggtgccgtgcagcagctgttcggccactgc
caagctcagaaggaggagatcaagaggcttttccagcagaaactggatgagctgggagtg
aaggcgctgacctacaacgacctgatccaagcgcagaaggagatctcggctcataaccag
cagctgagggagcagacggagcagctggagaagggcaaccgggagctgaggagccagagc
ctgcggctgctcaaggcacggtgcgaggagctgaagctggactggtccacgctgtccctt
gagggcctgctgaaggagaagcaggccctgaagagccagatctcggagaagcagaggcac
tgcctggagctgcagatcagcattgtggagctggagaagagccagaggcagcaggagctc
ctgcagctcaagtcctgcgtgccgcccgacgacgccctgtccctgcacctgcgcgggaag
ggtggcctgggccgagagctggaggccgagcccggccggccacacctggagctggactgt
gccaggttctccctgccccacttgagcaacatgagcccggagctgtccatgaacggccac
gcagccggctatgagctctgcggcgcgctgagccggccctcgcccaagcagaacaccccc
cagtacctggcctccccgctggaccaggaggtcgtgccctgcaccccgaaccacagtggc
cggccgaggctcgagaagttgtccggcctggccctgcccgactacaccaggctctccccg
gccaagctggtgctgcggcgccacctgagccaggaccacacagccaacagcagggcgacc
gccagcgagctgcactcacgagctgagcatgccaaggagaacggcctcccgtaccagagc
cccggcatcgccaacggcatcaaactgagcccacaggaccctcggccctcgtcccctgcg
gccttgcagatgacgggagagaagggcagtgagaagcgggagcaggctggcccggtggtg
tgtctgcagggtttgaaggagcgcacctacgccagcagtggggaggccatcaccagcctg
cccgtcagcatcccgctcagcaccgtgcagcctagcaagctgccagtcagcatccctctg
gccagcgtggtgctgcccagccgcgccgagaaggtgagaagcacccccagccccgtgcca
caggcccgagagtcctcgtccacactggagaagcagatgggtgctggcacccacggctct
gggtgcagcgctgctgggagcagaagcctcgccctggcccctgcaggctttgcctatgcc
ggctcagtggccatcagtggggccctggcaggcagcccggcaccactcgtctctggagcc
gagccccccaccctggacgagtcctccagctccggaagcctctttgccactgtggggtcc
cgcagctccacccctcagcacccccccctgctggcgcagcctcgcaactgcggctcggcc
tcgccggccccccagctctgcgccagtccccggcttggcacccagggcccgctccccgac
accagcaaaggagacctgccctctgaggccggcttctcggatcccgagagtgaagccaag
agaaggatcgtcttcaccatctcggccggctctagcagcgccaaacagtcaccttccagc
aagcacagccctctgtcctcgggcgcccgcggtgacggcggccagagccatgggcaggac
agccgcaagaggggcaggaggaagcgggcagcggcggggacccccggcttcagctcgggc
gtgtcccccaagcgccgggccctgccgtccgtcgccggcctcttcacccagtcttcaggg
tcccccctgaacctcaactccatggtcagcaacatcaaccagcccttggaaatcacggcc
atctcgtcccccgagagttccctgaagagctcgcctgtcccttaccaggacaacgaccag
ccgcccgtgctcaagaaggagaagcccctgagccagaccaacggggcccactattccccg
ctgacctcggatgaggagcagggctctgaggacgagcccagcagtgccagaattgagaga
aaaattgcaaccatctccttagaaagcaaatctcctccgaaaaccttggaaaatgggggc
ggcctggcgggaaggaaggtgccggccagcgagccggtcaacagcagcaagtggaagtcc
accttctcgcccatctccgacctcggcctggccaaggcagccgacagcccgctgcaggcc
gcctccgctctgagccacaactccctgttcgctttccggcccggcctggaggaacctggc
gcggctgacgccaagctggctgcccaccccaggaagagcttcccaggcgcgctgccgggg
gcgggcgggctgagccccagcagccatcccgccagcagcttcgccctgggcgggggcctg
gcggctgacctcagtttacacagcttcagcgatggtgcttctctctcccacaaggccccc
gaggcggccggcctgggcacccccctgagctttcccggcccgcggggcaaggagggcggc
gccgcagaccccggccccttcgtgaacaagaggcagctggacggactggccccgaagggc
gaggggggcccacctgtgtgcggacccgcggacaaggcctcagcgacgcacggcaaggcg
ggcaagggccgtgaccgcgagcccgatgtcaagaacggccacaacctcttcatggccgct
gctgctgctgccgccgccgccgccgccgccccccccgggggcctcctcagcggcccgggc
cttgccccggcggcgtcctcggcagggggcacggccccatccgtccagacccaccgcccc
ttcctgggcgccttcgcccccggcccgcagttcgcactgggccccatgtccctgcaggcc
aacctgggcccgtccgtgctgcagtccctgttcagctccgtgcccgccgccggcctggtg
cacgtctcaaccgctgccaccagactgaccaactcgcacgccatgggcagcttctcctcc
ggggtggccggcggtgcagtcggaggtgcctttaaccacgcggtgcctcccgcctccgct
catccgtttggagccagtttcggcagtggggctgcatgtcgcagcgccacgctgagccta
accccgctgcaggcggtggccagcaccccctcctcttcctttcaggccccgccccctgcg
gagccgaggccgcccccgccccctccgcacctgggccggccccctccggggccgcccgcc
ctccacgccccgccccctcctaacgccgccttgcctccgccccccgcgctgctcccggct
aactctgagcccgtgctcctgcagaacctcgcgtccctcccagctaaccaagctttctta
cctgcctcctctgctgcctctgtgccgcctgctaacgcctctctgtccatcaagctcgcc
tcacttccgcacaaggtgtcccgcccctccttcacggtgcaccacccgcccctgcccggg
ctggccctggcccaggccgcgcccgtgatcccgcaggccagctccacggggccgcccgcc
gtgtgggtttcccttggcatgccacctccgtatgccgcgcgccttgcgggggttaagccg
cgataa
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