Nocardia brasiliensis: O3I_038835
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Entry
O3I_038835 CDS
T02270
Name
(GenBank) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
nbr
Nocardia brasiliensis
Pathway
nbr00860
Porphyrin metabolism
nbr01100
Metabolic pathways
nbr01110
Biosynthesis of secondary metabolites
nbr01120
Microbial metabolism in diverse environments
nbr01240
Biosynthesis of cofactors
Module
nbr_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
nbr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
nbr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
O3I_038835
Enzymes [BR:
nbr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
O3I_038835
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
O3I_038835
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AFU05714
UniProt:
K0F7L5
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Position
complement(8709961..8711526)
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AA seq
521 aa
AA seq
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MSARATKKHPGRILFVGSGPGDPALLTVRAREVIGRATLAFTDPDVDKGVLALIGTAVEP
GPDGERPVDVRPALGEPAEVAKTLIAEARNGFDVVRVVAGDPLTTDSVIAEVNAVTRSHM
VFEVLPGLPNGSAVPSYAGIALGSGHTEADVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVEHGMAPQTPVAVTVRGTTRQQRTIEATLATLNSAASELVGPLVVTIGKVVASRSKM
SWWESRALYGWTVLVPRTKDQAGEMSERLVTHGAIPMEVPTIAVEPPRSPAQMERAVKGL
VDGRYQWVVFTSTNAVRAVWEKFAEFGLDARAFSGVKIACVGEATADKVRSFGINPELVP
SGEQSSEGLLADFPPYDDVFDPVNRVLLPRADIATETLAEGLRDRGWEIDDVTAYRTVRA
SPPPAETREMIKTGGFDAVLFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEFGLR
VDVQPEVAQVGPLVEALAEHAARLRAEGLLPPPRKKSRRSR
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcgcgagcaactaagaagcaccccggtcggatccttttcgtcgggtcgggtccc
ggtgacccggcgttgctgacggtgcgtgcccgcgaggtgatcgggcgcgccaccctggcg
ttcaccgaccccgatgtggacaagggcgtgctcgccctgatcgggaccgcggtcgagccc
ggcccggacggtgaacgcccggtcgacgtgcggcccgcgctcggtgaacccgccgaggtg
gccaagacgctgatcgcggaggcccgcaacggcttcgacgtggtccgggtggtcgccggc
gatccgctcaccaccgattcggtgatcgccgaggtgaacgcggtgacccgctcgcacatg
gtgttcgaggtgctgcccgggctgcccaacggctcggccgtgcccagctacgccggcatc
gcgctcggctccgggcacaccgaggcggacgtgcgcggcgaagtggactgggccgcgctc
gccgccgcgccgggaccgctggtgctgcacgcgacctcgggccacctggccgaaaccgcc
agtgccctggtggaacacgggatggcgccgcagaccccggtcgcggtgaccgtacgcggc
accacccgccagcagcgcaccatcgaggcgaccctggccacgctgaacagcgccgcctcc
gagctggtcggcccgctggtggtgaccatcggcaaggtggtcgcgtcccggtcgaagatg
tcctggtgggagtcgcgcgccctgtacggctggaccgtgctggtgccgcgcaccaaggat
caggcgggggagatgagcgagcggctcgtcacccacggtgccatcccgatggaggtgccg
accatcgcggtcgagccgccgcgcagccccgcccagatggagcgggcggtcaagggtctg
gtcgacggccggtaccagtgggtggtgttcacctccaccaacgcggtgcgcgcggtgtgg
gagaagttcgccgaattcggtttggacgcacgggctttctccggcgtgaagatcgcctgc
gtcggtgaggccaccgcggacaaggtgcgttcgttcggcatcaatccggaactggtcccc
agcggggaacagtcctccgagggcctgctcgccgacttcccgccctatgacgacgttttc
gatccggtgaaccgggtcctgttgccgcgcgccgatatcgcgaccgagacgctggccgag
gggctgcgcgaccggggctgggaaatcgacgacgtgaccgcctaccgcacggtgcgcgcc
tcgccgccgcccgcggagacccgcgagatgatcaagaccggtggtttcgacgcggtcctg
ttcacctcgtcctccacggtccgcaacctggtcggcatcgcgggcaagccgcacgcgcgc
accatcgtcgcgtgtatcggcccgaagaccgccgagaccgccatcgagttcggtttgcgc
gtcgacgtgcagcccgaggtcgcgcaggtcggtccgctggtcgaggcgctcgccgagcac
gccgcccggctccgcgccgagggcctgctgccgccgccgcggaagaagagccgccgcagc
cgctga
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