Nocardia farcinica IFM 10152: NFA_51680
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Entry
NFA_51680 CDS
T00207
Symbol
hemDX
Name
(GenBank) putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
nfa
Nocardia farcinica IFM 10152
Pathway
nfa00860
Porphyrin metabolism
nfa01100
Metabolic pathways
nfa01110
Biosynthesis of secondary metabolites
nfa01120
Microbial metabolism in diverse environments
nfa01240
Biosynthesis of cofactors
Module
nfa_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
nfa_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
nfa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NFA_51680 (hemDX)
Enzymes [BR:
nfa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NFA_51680 (hemDX)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NFA_51680 (hemDX)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BAD60020
NIH_Japan:
nfa51680
UniProt:
Q5YP71
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Position
complement(5465975..5467537)
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AA seq
520 aa
AA seq
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MSRATKKHPGRILFVGSGPGDPALLTVRAREVLGRATLAFTDPDVDKGVLALIGTAVEPN
EDGTSPVDVRPALGEPAEVAKTLIAEARGGHDVVRVVAGDPLTTDSVITEVTAVTRSHMV
FEVLPGLPNGSAVPSYAGIALGSGHTEADVRGEVDWAALAAAPGPLVLHATSGHLAETAS
ALVEHGMAPQTPVAVTVRGTTRQQRTIEATLATLNSAASELVGPLVVTIGKVVASRSKMS
WWESRALYGWTVLVPRTKDQAAEMSERLVTHGAIPMEVPTIAVEPPRSPAQMERAVKGLV
DGRYQWVVFTSTNAVRAVWEKFAEFGLDARAFSGVKIACVGEATADKVRSFGINPELVPS
GEQSSEGLLADFPPYDDVFDPVNRVLLPRADIATETLAEGLRDRGWEIDDVTAYRTVRAS
PPPAETREMIKTGGFDAVLFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAVEFGLRV
DVQPEVAQVGPLVEALAEHAARLRAEGLLPPPRKKSRRSR
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagccaccaagaagcaccccggtcggatcctgttcgtcgggtcgggtcccggg
gacccggcgctgctcaccgtgcgcgcgcgggaggtgctcggccgagcgacactggccttc
accgatcccgacgtggacaagggtgtgctcgcgctgatcggcacggcggtggagccgaac
gaggacggcaccagcccggtcgatgtgcgccccgccctgggcgagcccgccgaggtcgcc
aagaccctgatcgccgaggcgcggggcggtcacgacgtggtgcgcgtcgtcgccggtgat
ccgctcaccaccgattcggtgatcaccgaggtcaccgcggtcacccgttcgcacatggtc
ttcgaggtgctgcccggcctgccgaacggttcggccgtgcccagctacgcgggcatcgcg
ctcggctccggccacaccgaggccgatgtgcgcggcgaggtcgactgggccgcgctggcc
gccgcgcccggcccgctggtcctgcacgccacctccggccacctcgccgagaccgcgagc
gcgctggtcgagcacggcatggcgccgcagaccccggtcgcggtgaccgtgcgcggcacc
acccgtcagcagcgcaccatcgaggcgacgctggcgaccctcaacagcgcggcctccgag
ctggtcggcccgctggtggtgaccatcggcaaggtcgtcgcctcgcggtcgaagatgtcg
tggtgggagtcgcgggcgctctacggctggacggtgctggtgccgcgcaccaaggatcag
gccgccgagatgagcgagcggctggtcacccacggtgccatcccgatggaggtgcccacc
atcgccgtcgagccgccgcgcagccccgctcagatggagcgcgcggtgaagggcctggtc
gacgggcgctaccagtgggtggtcttcacctccaccaacgccgtgcgcgcggtgtgggag
aagttcgccgagttcggcctggacgcgcgcgccttctccggtgtgaagatcgcgtgcgtc
ggcgaggccaccgcggacaaggtgcgctcgttcggcatcaaccccgaactggtgccctcc
ggtgagcagtcctccgagggcctgctggccgacttcccgccctacgacgacgtgttcgac
ccggtcaaccgggtgctgctgccgcgcgcggacatcgccaccgagacgctggccgaaggg
ctgcgcgaccgcggctgggagatcgacgacgtgaccgcgtaccggacggtgcgcgcctcg
ccgccgcccgccgagacccgggagatgatcaagaccggcggtttcgacgcggtgctgttc
acctcctcgtccaccgtgcggaacctcgtcggtatcgcgggcaagccgcacgcgcgcacg
atcgtggcgtgcatcgggcccaagaccgccgagaccgccgtggaattcggcctgcgggtc
gacgtgcagcccgaggtcgcccaggtgggcccgctggtcgaggcactggccgagcacgcc
gcccggctgcgcgccgagggcctgctgcccccgccgcgcaagaagagccgtcgcagccgg
tag
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