Nannospalax galili (Upper Galilee mountains blind mole rat): 103735348
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Entry
103735348 CDS
T03372
Symbol
Srd5a1
Name
(RefSeq) steroid 5 alpha-reductase 1
KO
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00140
Steroid hormone biosynthesis
ngi01100
Metabolic pathways
Module
ngi_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
ngi_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103735348 (Srd5a1)
Enzymes [BR:
ngi01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
103735348 (Srd5a1)
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Paralog
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
103735348
NCBI-ProteinID:
XP_008832795
UniProt:
A0A8C6R068
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All DBs
Position
Un
AA seq
255 aa
AA seq
DB search
MAPAELRLLDALAYLEGFMGCLAWVLLLQVGTPYGRYSARWSGLRVPARPAWLLQELPSL
AWPLYECVRPAAARLGSWPNRVLLAMFLIHYVHRTLVFPALIRGGKPTPLFSCVLAFMFC
TVNGYMQSRYLSQFAVYAEDWLTSPCFLAGFVLWLMGMVINIHSDSILRNLRKPGETGYS
IPRGGVFEYVSAANYLGEILEWCGFALASWSLQGGVFALFSFCILFTRAKQHHQWYHEKF
EDYPKSRKIIIPFLL
NT seq
768 nt
NT seq
+upstream
nt +downstream
nt
atggcaccggcagagctgcggctcctagacgcactggcctacttggagggcttcatgggc
tgccttgcctgggtgctgctgctgcaggtcggcacgccctatggccgctactcggcccgg
tggtccgggctccgggtgcccgcgcggcccgcctggctgctgcaggagctgccctcgctg
gcctggccgctctacgagtgcgtgcgcccggcagccgcgcgcctggggagctggcccaac
cgcgtcctgctggccatgttccttatccactacgtgcaccggacgctggttttccctgcc
ctgatccgaggagggaaacccacaccgctcttttcctgtgtgttggccttcatgttctgt
accgtcaatggctatatgcagagcagatacctgagccagttcgcagtgtatgcggaggac
tggctgaccagtccctgcttcctggcaggctttgttttgtggttaatgggcatggtgata
aacatccattcagactctatcctgaggaatctgcgaaaaccaggggagactggatacagt
atacccaggggaggtgtgtttgaatacgtgtctgcagccaactatctcggggagatcctg
gagtggtgcggctttgcgctggccagctggtccctccaaggcggggtgtttgccctcttc
tcattttgcattttgttcaccagagccaaacaacatcatcagtggtaccatgagaaattt
gaagattacccaaagtcaaggaaaattataattccgtttctgctctaa
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