Natronomonas halophila: HWV23_16385
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Entry
HWV23_16385 CDS
T07279
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
nho
Natronomonas halophila
Pathway
nho00290
Valine, leucine and isoleucine biosynthesis
nho00660
C5-Branched dibasic acid metabolism
nho01100
Metabolic pathways
nho01110
Biosynthesis of secondary metabolites
nho01210
2-Oxocarboxylic acid metabolism
nho01230
Biosynthesis of amino acids
Module
nho_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
nho_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
nho00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HWV23_16385 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HWV23_16385 (leuC)
Enzymes [BR:
nho01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HWV23_16385 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HWV23_16385 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QLD87233
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Position
complement(3092278..3093702)
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AA seq
474 aa
AA seq
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MSKGTLYDKVWDRHKVTTLPNGQDQLFVGLHLIHEVTSPQAFGMLRERDIEVARPDLTHA
TVDHIVPTADQSRPLDNDAAEEMMAELEENVREAGIELDDPTTGNQGIVHVIGPEQGITQ
PGKTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTVAMEKKKVRKIEVTGELGEGVT
AKDIILTIIRRLGTEGGVGYVYEYAGEAIENLGMEGRMSICNMSIEGGARAGYVNPDETT
YEWLKGTDEFEDDPERFEELKPYWESIKSDENAEYDDVVTIDGSEIEPVVTWGTTPGQGI
GITEEIPAPEDLREDKQDTARRAQEHMRVEPGETMEGYNIDVAFLGSCTNARLPDLRAAA
EIVKDREVHDSVRAMVVPGSQRVKAAAEAEGLDEVFKEAGFDWREAGCSMCLGMNDDQLV
GDEACASSSNRNFVGRQGSKDGRTVLMSPEMVAAAAVTGEVTDVRELPKAEVEA
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgagcaagggcacgctctacgacaaggtctgggaccgacacaaggtcacgacgctgccg
aacgggcaggaccagctgttcgtcgggcttcacctcatccacgaggtcaccagcccgcag
gccttcgggatgctccgggaacgcgacatcgaagtcgcccgtccggacctgacccacgcg
acggtcgaccacatcgtcccgaccgccgaccagtcgcggccgctggacaacgacgccgcc
gaggagatgatggcggaactcgaggagaacgtccgcgaggccggcatcgaactggacgac
ccgacgacgggcaaccagggcatcgtccacgtcatcgggccggagcagggcatcacccag
cccggcaagaccatcgtctgcggtgacagccacacctccacccacggcgccttcggcgcg
ctggcgttcggtatcggcacctcccagattcgggacgtgctggcgacccagacggtcgcg
atggagaaaaagaaggtccgcaaaatcgaggtcaccggcgaactcggtgagggcgtcacc
gccaaggacatcatcctgaccatcatccgccgcctgggcaccgagggcggcgtcggctac
gtctacgagtacgccggcgaggccatcgagaacctcgggatggaaggtcggatgtccatc
tgtaacatgtccatcgagggcggcgctcgcgcgggctacgtcaaccccgacgagaccacc
tacgagtggctgaaggggacggacgaattcgaggacgaccccgagcgcttcgaggaactg
aagccctactgggagtccatcaagtccgacgagaacgccgaatacgacgacgtcgtcacc
atcgacggctccgaaatcgaacccgtcgtcacgtgggggaccacccccggccagggtatc
ggcatcaccgaggagattcccgcaccggaggacctccgcgaggacaaacaggacaccgcc
cgtcgcgcacaggaacacatgcgcgtcgaacccggcgagacgatggagggctacaacatc
gacgtggctttcctcggttcctgtacgaacgcccgactgcccgacctacgagcagcggcg
gaaatcgtcaaggaccgcgaggttcatgattcggtccgcgcgatggtcgtccccggtagc
cagcgcgtcaaggccgccgccgaagccgaaggcctcgacgaggtgttcaaggaagccggc
ttcgactggcgcgaggccggctgttcgatgtgtctcggcatgaacgacgaccaactggtc
ggcgacgaggcgtgtgcctcctcgtcgaaccgaaacttcgtcggccggcaaggttcgaag
gacggccggaccgtcctgatgagccccgagatggtcgccgccgcggcggtcaccggcgaa
gtgacggacgtgcgtgaactgccgaaggcggaggtggaggcataa
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