Nocardia huaxiensis: H0264_08400
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Entry
H0264_08400 CDS
T07784
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
nhu
Nocardia huaxiensis
Pathway
nhu00860
Porphyrin metabolism
nhu01100
Metabolic pathways
nhu01110
Biosynthesis of secondary metabolites
nhu01120
Microbial metabolism in diverse environments
nhu01240
Biosynthesis of cofactors
Module
nhu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
nhu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
nhu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
H0264_08400
Enzymes [BR:
nhu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
H0264_08400
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
H0264_08400
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QLY32269
UniProt:
A0A7D6ZZD6
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Position
1853162..1854724
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AA seq
520 aa
AA seq
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MSRASKKHPGRILFVGSGPGDPALLTVRAREVLGRATLAFTDPDVDKGVLALIGTAVEPA
ADGTLPVDVRPALGDAAEVAKTLITEARNGFDVVRLVSGDPMTTDSVIQEVNAVTRSHMM
FEVLPGLSAGTTVPAYAGIELGSSHTEVDVRGEVDWAAVAAAPGPLVLHATSGHLAETAS
ALVEHGMAPQTPVAVTVRGTTRQQRTIDATLATLNNAASEMVGPLIVTVGKEVEKRSKTS
WWESRALYGWTVLVPRTKEQAGEMSEKLVMHGAIPMEVPTIAVEPPRSPAQMERAVKGLV
DGRYQWVVFTSTNAVRAVWEKFGEFGLDARAFSGVKIACVGEATAEKVRSFGINPELVPS
GEQSSEGLLADFPPYDDVFDPVNRVLLPRADIATETLAEGLRDRGWEIDDVTAYRTVRAS
PPPAETREMIKTGGFDAVLFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEFGLRV
DVQPEVAQVGPLVEALAEHAAHLRAEGLLPPPRKKSRRSR
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagcgagcaagaagcaccccggtcggatccttttcgtggggtccggtccgggt
gatccggcgctgctcaccgtgcgggcccgcgaggtgctcgggcgggcgacgctggcgttc
accgatccggacgtcgacaagggcgtgctcgccctgatcggcaccgcggtggaacccgcc
gccgacgggacgctgcccgtcgatgtgcgtcccgccctgggcgatgccgccgaggtggcc
aagaccctgatcaccgaggcccgcaatggtttcgacgtggtgcgcctggtgtccggcgac
ccgatgaccaccgattcggtcatccaggaggtcaatgccgtcacccgctcgcacatgatg
ttcgaggtgctgcccggcctgtccgccggcaccaccgtgcccgcctacgcgggtatcgag
ctgggctccagccacaccgaggtggatgtgcgcggcgaggtcgactgggccgccgtcgcc
gccgcccccggcccgctggtgctgcacgccacctccggccacctggccgaaaccgcttcc
gcgctggtggaacacggtatggcgccgcagaccccggtcgcggtgaccgtgcgcggcacc
acccgccagcagcgcaccatcgacgccaccctggcgacgctcaacaatgcggcctccgag
atggtgggtccgctcatcgtcaccgtgggcaaggaggtcgagaagcgttccaagacttcg
tggtgggagtcgcgggcgctctacggctggaccgtgctggtgccgcgcaccaaggagcag
gccggtgagatgagcgagaagctcgtcatgcacggcgcgattccgatggaggtgccgacc
attgccgtcgagccgccgcgcagccccgcgcagatggagcgcgcggtcaagggcctggtg
gacggccgctaccagtgggtggtgttcacctccaccaacgcggtgcgcgcggtgtgggag
aagttcggcgaattcggtttggacgcgcgcgctttcagcggcgtgaagatcgcatgcgtc
ggtgaggcgaccgcggagaaggtgcgctcgttcggcatcaaccccgagctggtgccgtcg
ggtgagcagtcgtcggagggcctgctggccgacttcccgccctacgacgatgttttcgac
ccggtcaaccgagtcctgctgccgcgcgccgacatcgccaccgagaccctcgccgagggc
ctgcgcgatcgcggctgggagatcgacgacgtgactgcgtaccgcaccgtgcgcgcttct
ccgccgccggcggaaacccgcgagatgatcaagaccggcggtttcgacgcggtgctgttc
acctcgtcctccaccgtccggaacctggtcggcatcgccggtaagccgcacgcgcgcacc
atcgtcgcctgcatcggccccaagaccgccgagacggcaatcgaattcggcctgcgcgtg
gacgtgcagccggaggtggcccaggtcggcccactcgtcgaggcgctcgccgagcacgcc
gcccacctgcgcgccgagggcctgctgcccccgccgcgcaagaagagccgccgcagccgg
taa
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