Nomascus leucogenys (northern white-cheeked gibbon): 100587584
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Entry
100587584 CDS
T03265
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00010
Glycolysis / Gluconeogenesis
nle00020
Citrate cycle (TCA cycle)
nle00620
Pyruvate metabolism
nle00785
Lipoic acid metabolism
nle01100
Metabolic pathways
nle01200
Carbon metabolism
nle01210
2-Oxocarboxylic acid metabolism
nle04066
HIF-1 signaling pathway
nle04922
Glucagon signaling pathway
nle05230
Central carbon metabolism in cancer
nle05415
Diabetic cardiomyopathy
Module
nle_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100587584 (PDHA1)
00020 Citrate cycle (TCA cycle)
100587584 (PDHA1)
00620 Pyruvate metabolism
100587584 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100587584 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100587584 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100587584 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100587584 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100587584 (PDHA1)
Enzymes [BR:
nle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100587584 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100587584
NCBI-ProteinID:
XP_003261175
Ensembl:
ENSNLEG00000009805
LinkDB
All DBs
Position
X:17748734..17764521
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcagaagccggca
agcagagtgctagtagcatcccgtaattttgcaaatgatgcaacatttgaaattaagaaa
tgtgaccttcaccggctggaagaaggccctcctgtcacaacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaagcagatcag
ctgtataaacagaagattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaggccggcatcaaccccacagaccatctcatcacagcctaccgggct
cacggctttaccttcacccggggcctttccgtccgagaaattctcgcagagcttacagga
cgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgccaagaacttc
tacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggattgctctagcc
tgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggtgctgctaac
cagggccagatattcgaagcttacaacatggcagctttgtggaaattaccttgtattttc
atctgtgagaataatcgctatggaatgggaacgtctgttgagagagcagcagccagcact
gattactacaagagaggcgatttcattcctgggctgagagtggatggaatggatatcctg
tgcgtccgagaggcgacaaggtttgctgctgcctattgtagatctgggaaggggcccatc
ctgatggagctgcagacttaccgttaccacggacacagtatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggacaggatggtgaacagcaatcttgccagtgtagaagaactaaaggaaattgatgtg
gaagtgaggaaggagattgaggatgctgcccagtttgccacggccgatcctgagccacct
ttggaagagctgggctaccacatctactccagcgacccaccttttgaagttcgtggtgcc
aatcagtggatcaagtttaagtcagtcagttaa
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