Neisseria meningitidis FAM18 (serogroup C): NMC1176
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Entry
NMC1176 CDS
T00458
Symbol
leuC
Name
(GenBank) putative 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
nmc
Neisseria meningitidis FAM18 (serogroup C)
Pathway
nmc00290
Valine, leucine and isoleucine biosynthesis
nmc00660
C5-Branched dibasic acid metabolism
nmc01100
Metabolic pathways
nmc01110
Biosynthesis of secondary metabolites
nmc01210
2-Oxocarboxylic acid metabolism
nmc01230
Biosynthesis of amino acids
Module
nmc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nmc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NMC1176 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NMC1176 (leuC)
Enzymes [BR:
nmc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NMC1176 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NMC1176 (leuC)
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Paralog
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CAM10422
UniProt:
A1KU80
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All DBs
Position
1154991..1156400
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AA seq
469 aa
AA seq
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MTAQTLYDKLWNSHVVREEEDGTVLLYIDRHLVHEVTSPQAFEGLKMAGRKLWRIDSVVS
TADHNTPTGDWDKGIQDPISKLQVDTLDKNIKEFGALAYFPFMDKGQGIVHVMGPEQGAT
LPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSKSMLIAVDGKLKAGV
TAKDVALYIIGQIGTAGGTGYAVEFGGEAIRSLSMEGRMTLCNMAIEAGARSGMVAVDQT
TIDYVKDKPFAPEGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVL
DISSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRIEDLREA
AAIAKDRKKAANVQRVLIVPGSGLVKEQAEKEGLDKIFIEAGFEWREPGCSMCLAMNADR
LTPGQRCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAVTGRFTDIRMMA
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgacagcacaaaccctctacgacaaactttggaacagccacgtcgtccgcgaagaagaa
gacggcaccgtcctgctctacatcgaccgccatttggtgcacgaagttaccagccctcag
gcatttgaaggcttgaaaatggcggggcgcaagctgtggcgcatcgacagcgtcgtctcc
accgccgaccacaacaccccgaccggcgattgggacaaaggcatccaagacccgatttcc
aagctgcaagtcgatactttggacaaaaacattaaagagtttggcgcactcgcctatttt
ccgtttatggacaaaggtcagggcatcgtacacgttatgggccccgaacaaggcgcgacc
ctgcccggtatgaccgtcgtctgcggcgactcgcacacttccacccacggcgcattcggc
gcactggcgcacggcatcggcacttccgaagtcgagcacacgatggcgacccagtgcatt
accgcgaaaaaatccaaatccatgctgattgccgttgacggcaaattaaaagcgggcgtt
accgccaaagacgtggcactttacatcatcgggcaaatcggcacggcgggcggtacaggc
tacgccgtcgagtttggcggcgaagccatccgcagcctttctatggaaggccgcatgact
ttatgcaatatggcgatcgaagccggtgcgcgctcaggcatggttgccgtcgaccaaacc
accatcgactatgtaaaagataaacccttcgcacccgaaggcgaagcgtgggacaaagcc
gtcgagtactggcgcacgctggtgtctgacgaaggtgcggtattcgacaaagaataccgt
ttcaacgccgaagacatcgaaccgcaagtcacttggggtacctcgcctgaaatggtttta
gacatcagcagcaaagtgccgaatcctgccgaagaaaccgatccggtcaaacgcagcggt
atggaacgggcccttgaatacatgggcttggaagccggtacgccattaaacgaaatcccc
gtcgacatcgtattcatcggctcttgcaccaacagccgcatcgaagacttgcgcgaagcc
gccgccatcgccaaagaccgcaaaaaagccgccaacgtacagcgcgtgttaatcgtcccc
ggctccggtttggttaaagaacaagccgaaaaagaaggcttggacaaaattttcattgaa
gccggttttgaatggcgcgaaccgggctgttcaatgtgtctcgccatgaacgccgaccgc
ctgaccccggggcaacgctgcgcctccacctccaaccgcaattttgaaggccgtcaaggc
aacggcggacgtacccacctcgtcagccccgctatggcagccgccgccgccgttaccggc
cgctttaccgacatccgcatgatggcgtaa
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