Neisseria meningitidis alpha14 (cnl strain): NMO_1092
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Entry
NMO_1092 CDS
T00954
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
nmi
Neisseria meningitidis alpha14 (cnl strain)
Pathway
nmi00290
Valine, leucine and isoleucine biosynthesis
nmi00660
C5-Branched dibasic acid metabolism
nmi01100
Metabolic pathways
nmi01110
Biosynthesis of secondary metabolites
nmi01210
2-Oxocarboxylic acid metabolism
nmi01230
Biosynthesis of amino acids
Module
nmi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NMO_1092 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NMO_1092 (leuC)
Enzymes [BR:
nmi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NMO_1092 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NMO_1092 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CBA06147
UniProt:
C6S796
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All DBs
Position
1126608..1128017
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AA seq
469 aa
AA seq
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MTAQTLYDKLWNSHVVREEEDGTVLLYIDRHLVHEVTSPQAFEGLKMAGRKLWRIDSVVS
TADHNTPTGDWDKGIQDPISKLQVDTLDKNIKEFGALAYFPFMDKGQGIVHVMGPEQGAT
LPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSKSMLIAVDGKLKAGV
TAKDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMEGRMTLCNMAIEAGARSGMVAVDQT
TIDYVKDKPFAPKGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVL
DISSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRIEDLREA
AAIAKDRKKAANVQRVLIVPGSGLVKEQAEKEGLDKIFIEAGFEWREPGCSMCLAMNADR
LTPGQRCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAVTGRFTDIRMMA
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgacagcacaaaccctctacgacaaactttggaacagccacgtcgtccgcgaagaagaa
gacggcaccgtcctgctctacatcgaccgccatttggtgcacgaagttaccagccctcag
gcatttgaaggcttgaaaatggcggggcgcaagctgtggcgcatcgacagcgtcgtctcc
accgccgaccacaacaccccgaccggcgattgggacaaaggcatccaagacccgatttcc
aagctgcaagtcgatactttggacaaaaacattaaagagtttggcgcactcgcctatttt
ccgtttatggacaaaggtcagggcatcgtacacgttatgggccccgaacaaggcgcgacc
ctgcccggtatgaccgtcgtctgcggcgactcgcacacttccacccacggcgcattcggc
gcactggcacacggcatcggcacttccgaagtcgagcacaccatggcaacccagtgtatt
accgcgaaaaaatccaaatccatgctgattgccgttgacggcaaattaaaagcgggcgtt
accgccaaagacgtggcactttacatcatcgggcaaatcggcacggcaggcggtacaggc
tacgccatcgagtttggcggcgaagccatccgcagcctttctatggaaggccgcatgact
ttatgcaatatggcgattgaggcaggcgcgcgctcaggcatggttgccgtcgaccaaacc
accatcgactatgtaaaagataaacccttcgcacctaaaggcgaagcatgggacaaagcc
gtcgagtactggcgcacgctggtgtctgacgaaggtgcggtattcgacaaagaataccgt
ttcaacgccgaagacatcgaaccgcaagtcacttggggtacctcgcctgaaatggtttta
gacatcagcagcaaagtgccgaatcctgccgaagaaaccgatccggtcaaacgcagcggt
atggaacgcgcccttgaatacatgggcttggaagccggtacgccattaaacgaaatcccc
gtcgacatcgtattcatcggctcttgcaccaacagccgcatcgaagacttgcgcgaagcc
gccgccatcgccaaagaccgcaaaaaagccgccaacgtacagcgcgtgttaatcgtcccc
ggctccggtttggttaaagaacaagccgaaaaagaaggcttggacaaaattttcatcgaa
gccggttttgaatggcgcgaaccgggctgttcgatgtgtctcgccatgaacgccgaccgc
ctgaccccggggcaacgctgcgcctccacctccaaccgcaattttgaaggccgtcaaggc
aacggcggacgtacccacctcgtcagccccgctatggcagccgccgccgccgttaccggc
cgctttaccgacatccgcatgatggcgtaa
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