Nyctereutes procyonoides (raccoon dog): 129521674 Help Entry 129521674         CDS       T09008                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo04010   MAPK signaling pathway npo04014   Ras signaling pathway npo04015   Rap1 signaling pathway npo04022   cGMP-PKG signaling pathway npo04066   HIF-1 signaling pathway npo04068   FoxO signaling pathway npo04072   Phospholipase D signaling pathway npo04150   mTOR signaling pathway npo04151   PI3K-Akt signaling pathway npo04152   AMPK signaling pathway npo04211   Longevity regulating pathway npo04213   Longevity regulating pathway - multiple species npo04520   Adherens junction npo04910   Insulin signaling pathway npo04913   Ovarian steroidogenesis npo04923   Regulation of lipolysis in adipocytes npo04930   Type II diabetes mellitus npo04931   Insulin resistance npo04932   Non-alcoholic fatty liver disease npo04960   Aldosterone-regulated sodium reabsorption npo05010   Alzheimer disease npo05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:npo00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     129521674 (INSR)    04014 Ras signaling pathway     129521674 (INSR)    04015 Rap1 signaling pathway     129521674 (INSR)    04066 HIF-1 signaling pathway     129521674 (INSR)    04068 FoxO signaling pathway     129521674 (INSR)    04072 Phospholipase D signaling pathway     129521674 (INSR)    04022 cGMP-PKG signaling pathway     129521674 (INSR)    04151 PI3K-Akt signaling pathway     129521674 (INSR)    04152 AMPK signaling pathway     129521674 (INSR)    04150 mTOR signaling pathway     129521674 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     129521674 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     129521674 (INSR)    04923 Regulation of lipolysis in adipocytes     129521674 (INSR)    04913 Ovarian steroidogenesis     129521674 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     129521674 (INSR)   09149 Aging    04211 Longevity regulating pathway     129521674 (INSR)    04213 Longevity regulating pathway - multiple species     129521674 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     129521674 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     129521674 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     129521674 (INSR)    04932 Non-alcoholic fatty liver disease     129521674 (INSR)    04931 Insulin resistance     129521674 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:npo01001]     129521674 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:npo04090]     129521674 (INSR) Enzymes [BR:npo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      129521674 (INSR) Protein kinases [BR:npo01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    129521674 (INSR) CD molecules [BR:npo04090]  Proteins   129521674 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  129521674 NCBI-ProteinID:  XP_055199333 LinkDB All DBs Position Unknown AA seq 1382 aa AA seqDB search MGARAGRGAAAAPLLLAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATSKSFRPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFW ERQAEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQI LKELEESSFRKTFEDYLHNVVFVPRKSSSSPGAEDTRPSRKRRALSDAGNVTAAIPTVPG FPNTSTSAPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEPETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMESVPLDRASHSQREEAGGRDAGSSLGLKRSYEEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgcccgggccgggcggggggcggccgccgcgccgctgctgctggcggtggccgcg ctgctgctgggtgccgcgggccacctgtaccccggagaggtgtgtcctggcatggatatc cggaacaacctaacgaggctgcatgagctggccaactgctcggtcattgaaggacatttg cagatactgttaatgttcaaaacgaggcccgaggatttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctcgcgcctcttcttcaactatgcgctg gtcatcttcgagatggtccacctgaaggagcttggcctctacagcttgatgaacatcacc cggggctctgtccgcatcgagaagaacaatgagctctgctacctggccaccatcgactgg tcccgcatcctggattctgtggaggataattatatcgtgctgaacaaagacgacaacgag gagtgtggggacatctgtccaggcactgccaagggcaagaccaactgccctgccactgtc atcaatgggcagtttgtcgagcggtgttggacacacagccactgccagaaagtttgtccg accatctgcaagtcgcatggttgcaccgccgagggcctctgctgccacagcgagtgttta ggcaactgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gatggcaggtgcgtggagacctgcccgcccccgtactaccacttccaagactggcgctgc gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactcccggagacagggc tgccaccagtacgtcatccacaataacaagtgcatccccgagtgcccctctggctacacg atgaattccagcaacctgatgtgcactccgtgcctgggcccctgtcccaaggtctgccac attctggaaggcgagaagaccatcgactcagtgacgtctgcccaggagcttcgaggctgc actgttgtcaacggaagtctaatcatcaacattcgagggggaaacaacctggcggctgag ctggaggccaacctcggactcattgaagagatttccgggtacctgaaaatccggagatcc tatgctcttgtgtctctttcctttttccggaagttacggctgattcgaggggagaccttg gagatcgggaactactctttctatgccttggacaaccagaacctaaggcagctatgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa ctctgcttgtctgagatccacaagatggaggaagtctcaggaaccaaggggcgccaggag aggaacgacattgccctgaagaccaacggggaccaggcgtcttgtgaaaacgaactactt aaattttcttacattcggacgtcttatgacaagatcttgctgaaatgggagccctactgg ccccccgacttccgagacctcctggggttcatgctcttctacaaagaggccccttatcag aatgtgaccgagtttgatgggcaggatgcgtgtggctccaacagctggacggtggtggac attgacccacctctgcggtccaacgaccccaaatcgcagaaccacccggggtggctgatg cggggtctcaagccctggacccaatatgccatctttgtcaagaccttggtcaccttttct gatgaacgccgcacgtatggagccaagagtgacatcatctatgtgcagacagatgccact agtaaatccttccgtcccctggatccaatctcggtttcgaattcctcgtcccagattatt ctgaagtggaagcctccctctgaccccaatggcaatatcacacactacctggttttctgg gagaggcaggccgaagacagtgagctctatgagttggattattgcctcaaagggttgaag ctgccctcccggacctggtctccgccgttcgaggccgagggctcccagaagcacaaccag agtgaatacgaggagtctgccggcgaatgctgctcctgccccaaaacggactctcagatc ctcaaggagctagaggagtcctcttttaggaagacgtttgaggattacctgcacaacgtg gtgttcgtccccagaaaatcctcttcgagccctggtgctgaggacactaggccgtcgagg aaacgcagggcgctcagtgatgctggcaacgtgacagcagctatacccacagttcccggt ttccccaacacctcgaccagcgcgcccacgagcccggaggagcacaagcccttcgagaaa gtggtgaacaaagaatccctggtcatctccggtctgcgccacttcactggctaccgcatc gagctgcaggcttgcaaccaagactcccccgaggagaggtgcagcgtggcggcctatgtc agcgccaggaccatgcctgaagccaaggcagacgacatcgttggccccgtgacccacgaa atcttcgagaacaatgtcgttcacttgatgtggcaggagccaaaggaacccaatggtctg attgtgctttatgaagtgagttaccgacggtatggcgatgaggagctgcacctgtgtgtc tcccggaggcattttgctctggagcgtggctgcaggctacgcgggctgcctccggggaat tacagcgtgcgagtccgggccacctccctggcgggcaatggctcctggacagaagccacc tacttctacgtgacagactatttagatgtcccatcgaatattgcaaaaattatcatcggc cccctcatctttgtctttctcttcagtgttgtgattggaagtatttacctgttcctgaga aagaggcagccggatgggccactgggaccgctgtatgcttcttcaaaccctgagtacctc agtgccagtgatgtgtttccatgttctgtgtatgtgccggacgagtgggaggtgccgcgg gagaagatcaccctcctgcgcgagctggggcagggctccttcggcatggtgtacgagggc aacgccagggacatcgtcaagggcgagcccgagacccgcgtggccgtcaagaccgtcaac gagtctgccagcctgcgagagaggatcgagtttctcaacgaggcatcagtcatgaagggc ttcacctgtcaccacgtggtccgcctcctgggggtggtgtccaaaggccaaccgacgctg gtggtgatggagctgatggctcacggagacctgaagagctacctccgctccctgcggccg gaggctgagaataaccccggccgccctccgcctaccctgcaagagatgattcagatggcg gcggagatcgccgacgggatggcctacctgaacgccaagaagtttgtgcaccgggatcta gcagcccgaaactgcatggtcgcccacgatttcactgtcaaaattggagactttgggatg accagagacatctatgagacggattactaccggaaaggaggcaagggtctgctccccgtg cggtggatggcaccggagtccctgaaggacggggtctttaccacttcttctgacatgtgg tcctttggcgtggtcctttgggaaatcaccagcttggcagagcagccttaccaaggcctg tctaatgaacaggtgttgaaatttgtcatggacggagggtatctggatcaacctgacaat tgtccggagagagtcactgacctgatgcgcatgtgctggcagttcaatcccaagatgcgg cccaccttcctggagatcgtcgacctgctcaaggatgacctgcaccccagctttccagaa gtttccttcttccacagcgaggagaacaaggcacccgagagcgaggagttggagatggag tttgaggacatggagagtgtccccctggatcgggcctcacactctcagcgggaggaggcc gggggccgggatgcagggtcctcgctgggcctaaagcggagctacgaggagcacatcccc tacactcacatgaacgggggcaagaaaaatggacggattctgactctgccaaggtcgaat ccttcctaa

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