Nocardia mangyaensis: BOX37_29570
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Entry
BOX37_29570 CDS
T04582
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
nsl
Nocardia mangyaensis
Pathway
nsl00860
Porphyrin metabolism
nsl01100
Metabolic pathways
nsl01110
Biosynthesis of secondary metabolites
nsl01120
Microbial metabolism in diverse environments
nsl01240
Biosynthesis of cofactors
Module
nsl_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
nsl_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
nsl_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
nsl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
BOX37_29570
Enzymes [BR:
nsl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
BOX37_29570
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
BOX37_29570
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
APE37392
UniProt:
A0A1J0VZ58
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Position
complement(6645460..6647028)
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AA seq
522 aa
AA seq
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MSSRATKKQPGRILFVGSGPGDPALLTVRAREVLERATLAFTDPDVDKGVLALIGAAVEP
GEDGERPVDVRPALGEPAEVAKTLIAEARNGHDVVRIVTGDPLTTDSVINEVNSVTRSHV
VFEVLPGLPNGSAVPSYAGIALGSGHTEADVRGEVDWSALAAAPGPLVLHATSGHLAETA
SALVEHGLAPQTPVAVTVRGTTRQQRTIEATLASLNNAASELVGPLVVTVGKEVDKRSKM
SWWESRALYGWTVLVPRTKDQAGEMSERLVTHGAIPMEVPTIAVEPPRSPAQMERAVKGL
VDGRYQWVVFTSTNAVRAVWEKFAEFGLDARAFSGVKIACVGEATAERVRSFGINPELVP
SGEQSSEGLLADFPPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
SPPPAETREMIKTGGFDAVLFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEFGLR
VDVQPETAQVGPLVEALAEHASRLRAEGLLPPPRKKSRRSSR
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
atgagcagccgagccaccaagaagcaaccagggcggatccttttcgtcggatccggcccc
ggcgacccggccctgctgaccgtgcgcgcccgtgaggtgctcgaacgggcgacgctggcg
ttcaccgaccccgatgtcgacaagggcgtgctcgccctgatcggcgcggcagtcgagccg
ggcgaggacggcgagcgtccggtcgacgtgcggcctgccctcggcgagcccgccgaggtc
gccaagacgctgatcgccgaggcccgcaacggccacgacgtggtccgcatcgtcaccggc
gatccgttgaccaccgactcggtgatcaacgaggtgaactcggtgacccgctcgcacgtg
gtgttcgaggtgctgcccggcctgcccaacggctccgcggtgcccagctacgccggtatc
gcgctcggctccgggcacaccgaggccgacgtgcgcggcgaggtcgactggtcggcgctg
gccgccgcgcccggcccgctggtgctgcacgccacctccgggcatctggccgagaccgcg
agcgcgctggtcgagcacgggctggccccgcagactccggtcgcggtgacggtgcgtggc
acgacccggcagcagcgcaccatcgaggccacgttggcctcgctgaacaacgccgcctcc
gaactggtcggcccgctggtcgtcaccgtcggcaaagaggtcgacaagcggtcgaagatg
tcgtggtgggaatcgcgtgccctctacggctggaccgtgctggtgccgcgcaccaaggat
caggcgggggagatgagcgagcggctcgtcacccacggcgcgatcccgatggaggtgccg
accatcgccgtcgagccgccgcgcagtccggcgcagatggagcgggcggtgaagggcctg
gtcgacggtcgctaccagtgggtggtgttcacctccaccaacgcggtgcgtgccgtatgg
gagaagttcgccgagttcggcctggacgctcgcgcgttctccggggtgaagatcgcctgc
gtgggcgaggccaccgcggagcgggtgcgctccttcggcatcaaccccgaactggtgccc
agcggcgaacagtcctccgagggcctgctggccgacttcccgccctacgacgacgtgttc
gacccggtgaaccgggtgctgctgccgcgcgccgacatcgccaccgaaaccctcgccgag
ggcttgcgcgagcgcggctgggagatcgacgacgtcaccgcctaccgcaccgtgcgcgcc
tcgccgccgccggcggagacccgcgagatgatcaagaccggcggtttcgacgcggtcctg
ttcacttcgtcctccacggtccgcaatctggtcgggatcgcgggcaagccgcacgcgcgc
accatcgtggcctgcatcggccccaagaccgccgagaccgcgatcgagttcggcctgcgc
gtggacgtgcagcccgagaccgcgcaggtcggtccactggtcgaggcgctggccgagcac
gcgtcgcgcctgcgcgcggagggcttgctgccgccgcctcggaagaagagccgccgcagc
agccgctag
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