Neomonachus schauinslandi (Hawaiian monk seal): 110593671
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Entry
110593671 CDS
T08474
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010
MAPK signaling pathway
nsu04014
Ras signaling pathway
nsu04015
Rap1 signaling pathway
nsu04022
cGMP-PKG signaling pathway
nsu04066
HIF-1 signaling pathway
nsu04068
FoxO signaling pathway
nsu04072
Phospholipase D signaling pathway
nsu04150
mTOR signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu04152
AMPK signaling pathway
nsu04211
Longevity regulating pathway
nsu04213
Longevity regulating pathway - multiple species
nsu04520
Adherens junction
nsu04910
Insulin signaling pathway
nsu04913
Ovarian steroidogenesis
nsu04923
Regulation of lipolysis in adipocytes
nsu04930
Type II diabetes mellitus
nsu04931
Insulin resistance
nsu04932
Non-alcoholic fatty liver disease
nsu04960
Aldosterone-regulated sodium reabsorption
nsu05010
Alzheimer disease
nsu05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110593671 (INSR)
04014 Ras signaling pathway
110593671 (INSR)
04015 Rap1 signaling pathway
110593671 (INSR)
04066 HIF-1 signaling pathway
110593671 (INSR)
04068 FoxO signaling pathway
110593671 (INSR)
04072 Phospholipase D signaling pathway
110593671 (INSR)
04022 cGMP-PKG signaling pathway
110593671 (INSR)
04151 PI3K-Akt signaling pathway
110593671 (INSR)
04152 AMPK signaling pathway
110593671 (INSR)
04150 mTOR signaling pathway
110593671 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
110593671 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110593671 (INSR)
04923 Regulation of lipolysis in adipocytes
110593671 (INSR)
04913 Ovarian steroidogenesis
110593671 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
110593671 (INSR)
09149 Aging
04211 Longevity regulating pathway
110593671 (INSR)
04213 Longevity regulating pathway - multiple species
110593671 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110593671 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110593671 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110593671 (INSR)
04932 Non-alcoholic fatty liver disease
110593671 (INSR)
04931 Insulin resistance
110593671 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110593671 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nsu04090
]
110593671 (INSR)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110593671 (INSR)
Protein kinases [BR:
nsu01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
110593671 (INSR)
CD molecules [BR:
nsu04090
]
Proteins
110593671 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
DUF4476
B2
Motif
Other DBs
NCBI-GeneID:
110593671
NCBI-ProteinID:
XP_021560635
EnsemblRapid:
ENSNSCG00000020653
UniProt:
A0A2Y9IGT8
LinkDB
All DBs
Position
1:complement(208346661..208471695)
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AA seq
1368 aa
AA seq
DB search
MGTGAGRGAATAPLLVAVAALLLGATGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSQCL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNRCKNSRRQG
CHQYVIHNSKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC
TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQVEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRPSRKRRALGDVANVTAAAPTVPGFPNTSTSAPTSPE
EHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVSARTMPEAKADDI
VGPVTHEIFENNVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLR
GLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGS
IYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSF
GMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS
KGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKK
FVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFT
TSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQ
FNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRASH
AQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNPS
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgggcaccggagctgggcggggggcggcgaccgcgccgctgctggtggcggtggccgcg
ctgctgctgggtgccacgggccacctgtaccccggagaggtgtgccctggcatggatatc
cggaacaacctcacgaggttgcatgagctggccaactgctcggtcattgaaggacatttg
cagatactgttgatgttcaaaacgaggcccgaggatttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgcttttccgggtctatgggctggagagtctgaag
gacctgttccccaacctcacggtcatccggggctcgcgtctcttcttcaactatgcgctg
gtcatcttcgagatggttcacctgaaggagcttggcctctacagcttgatgaacattacc
cggggctccgtccgcattgagaagaacaatgagctctgctacctggccaccatcgactgg
tcgcgcatcctggattctgtggaggataattacattgtgctgaacaaagatgacaacgag
gagtgtggggacatttgtccaggcactgcaaagggcaagaccaactgccccgccactgtc
atcaacgggcagtttgtcgagcggtgttggacacacagccactgccagaaagtttgtccc
accatctgcaagtcgcacggctgcaccgccgagggtctctgctgccacagccagtgtttg
ggcaattgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg
gatggcaggtgcgtggagacctgcccgcccccatactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacagatgcaagaactcccggagacagggc
tgccaccaatacgtcattcacaacagcaagtgcatccccgagtgcccctctggctacacg
atgaattccagcaacctgatgtgcactccatgcctgggcccctgtcccaaagtctgccac
atcctggagggcgagaaaaccattgactcggtgacatctgcccaggagctccgaggctgc
actgttgtcaacggaagcctcatcatcaacatccgagggggcaacaacctggcagctgag
ctggaggccaacctaggactcattgaagaaatttccgggtatctgaagatccggagatcc
tacgctcttgtgtcactttcttttttccggaagttacggctaattcgaggagagaccttg
gaaatcgggaactactctttctacgccttggacaaccagaacctaaggcagctctgggac
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactacaatcccaaa
ctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
aggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactcctt
aaattttcttacattcggacatcgtatgacaagatcttgctgaaatgggagccgtactgg
ccccctgacttccgagacctcctggggttcatgcttttctacaaagaggccccttatcag
aatgtgaccgagttcgacgggcaggacgcgtgtggctccaacagctggacggtggtggac
attgacccgcctctgcggtccaatgaccccaagtcgcagaaccacccagggtggctgatg
cggggtctcaagccctggacccagtatgccatcttcgtcaagaccttggtcaccttttct
gatgaacgccgcacgtatggggccaagagtgacatcatctatgtgcagacagatgccact
aacccttctgtccccctggatccaatctccgtttctaactcctcgtcccagattattctg
aagtggaagcctccctctgatcccaatggcaacatcacacactacctggttttctgggag
aggcaggtagaagacagtgagctgtatgagctggattactgcctcaaagggttgaagctg
ccctcccggacctggtctccgccgttcgaggccgagggctcccagaagcacaaccagagt
gaatacgaggagtctgccggcgaatgttgctcctgccccaagacggactctcagatcctc
aaggagctggaggagtcctcttttaggaagacctttgaggattacctgcacaatgtggtg
ttcgtccccaggccatcgcggaaacgccgggccctcggggacgttgccaacgtgacggcg
gccgcgcccacggttccgggtttccccaacacctcgaccagcgcacccacgagcccagag
gagcacaagcccttcgagaaagtggtgaacaaagaatccctggtcatctctgggctgcgc
cacttcactggctatcgcatcgagctgcaggcttgcaaccaagactcccccgaggagagg
tgcagcgtggcggcctacgtgagcgccaggaccatgcctgaagccaaggcagatgatatt
gttggccccgtgacccacgaaatcttcgagaacaatgttcacctgatgtggcaggagcca
aaggaacccaacggtctgatcgtgctgtatgaagtgagttaccggcgctatggtgatgag
gagctgcacctctgtgtctcccgcagacattttgctctggagcggggctgcaggctgcgt
gggctgccgccggggaattacagcgtgcgagtccgggccacctccctggcgggcaacggc
tcgtggacagaagccacctatttctacgtgacagactatttagatgtcccgtcgaatatt
gcaaaaatcatcatcggccccctcatctttgtctttctcttcagtgttgtgattggaagt
atttacctgttcctgagaaagaggcagccggatgggccactgggaccgctgtacgcgtct
tcaaaccccgagtacctcagtgccagtgacgtcttcccatgttctgtgtatgtgccggac
gagtgggaggtgcctcgggagaagatcacgctcctgcgtgagctggggcagggctccttc
ggcatggtgtacgaaggcaacgcgagggacattgtcaagggcgaggcggagacccgcgtg
gcggtgaagacggtcaacgagtcggccagtttgcgagagaggatcgagtttctcaacgag
gcctcagtcatgaagggcttcacctgtcatcacgtggtccgcctcctgggggtggtgtcc
aaaggccagccaacgctggtggtgatggagctgatggctcacggcgacctgaagagctac
ctccgctccctgcggccggaggctgagaataaccccggccgccctccccctaccctgcaa
gagatgattcagatggcggcggagattgccgacgggatggcctacctgaatgccaagaag
tttgtgcaccgagatctcgcagcccgaaactgcatggtcgcccacgatttcaccgtcaaa
attggagactttgggatgaccagagacatctatgaaacggattactaccggaaaggaggc
aagggtctgctccccgtgcggtggatggcaccggaatccctgaaggacggggtctttacc
acttcttctgacatgtggtccttcggcgtggtcctttgggaaatcaccagcttggcagaa
cagccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatggatggagggtat
ctggatcaacccgacaattgtccagagagagtcaccgacctgatgcgaatgtgctggcag
ttcaatcctaagatgcggcccaccttcctggagatcgtcgacctgctcaaggacgacctg
caccccagctttccagaagtgtccttcttccacagtgaggagaacaaggcgcctgagagt
gaggagctggagatggagttcgaggacatggagagtgtccccctggatcgggcctcacac
gctcagagggaggaggccgggggccgggatggagggtcctcactgggcctaaagcggaac
tatgaggagcatatcccctacacccacatgaacgggggcaagaaaaacggacggatcctg
actctgccgaggtcgaatccttcctaa
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integrated database retrieval system
