Neomonachus schauinslandi (Hawaiian monk seal): 110593857
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Entry
110593857 CDS
T08474
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00310
Lysine degradation
nsu01100
Metabolic pathways
nsu05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
110593857 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
110593857 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
nsu03036
]
110593857 (DOT1L)
Enzymes [BR:
nsu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
110593857 (DOT1L)
Chromosome and associated proteins [BR:
nsu03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
110593857 (DOT1L)
HMT complexes
Dot1-containing complex
110593857 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
110593857
NCBI-ProteinID:
XP_021560960
EnsemblRapid:
ENSNSCG00000006181
UniProt:
A0A2Y9IHS4
LinkDB
All DBs
Position
1:complement(213133794..213186011)
Genome browser
AA seq
1604 aa
AA seq
DB search
MAGVDLEGQGLSGQARSVMGLEASAELPQLSSDIYQEVLGPLVPISGPHPKFLSRLCADA
AEFFTCCEILQGAGRGYALSVVQQLQHSPCITGGCKSCPFVFQDKHHDAAHEIIETIRWV
CEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSN
GLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGS
GVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFL
SEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNL
SDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRR
QQRDNKSTTATPTKLPESKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGR
KMAGRKRGRPKKMSTANPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLP
PSVQRQPPDQLLLAPTPPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNTR
LLGAAQQLFGHCQAQKEEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQ
LQKDNRELRSQSLQLLKARCEELKLDWSTLSLENLLKEKQALRTQISEKQRHCLELQISI
VELEKSQRQQELLQLKSCVPPDDALSAHLRGKGALGRELEADPSRLHLDLDCSKFSLPHL
SSASPELSMNGHAASYEVCGTLSRPSSKQNTPQYLASPLDQEVIPCTPSHSSRPRLEKMS
GLALPDYTRLSPAKLVLRRHLSQDHVASGKTAASELHPRAEHAKENGLPYQSPGIANGIK
LSPQDPRPSSPMALQMTGERGGEKGVKERSYASSGEAITSLPVSIPLSTVQPSKLPVSIP
LASVVLPSRAEKVRSTPSPVPQTRESSSTLEKQMGANAHGVASKGLTPAPAGFYAGSVAV
SGALAGSPAPLAPGTEPGAFDEVSGSGSLFASMGPCSTPQHPPLLPQSRGSGAASPAHPL
CASPRLSSAAQGPLPEANKGDLPSEAGFSDPEGEAKRRIVFTISAGGSAKQSPPGKPSPL
PTGARGDSGQGHGPDSRKRGRRKRAAAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNL
NSMVSNINQPLEITAISSPESLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEE
QGSEDEPGSARIERKIATISLESKSPPKNLESGGGLAGRKPTPASEPANSSKWKSTFSPI
SDLGLAKCADSPLQAGSALSQNSLFAFRPPLEEPGLAEAKLAAHPRKSFSGALSGAGGLS
PSSNPPNGFAFSGGLAADLSLHSFSDGASLSHKVPEAASLGAPLSFPAPRGKEGSAAESG
AFVNKRQLEGLGGPKGREAGELGLPACGPPDKPSLVHSKPGKGRDREPDLKNGHNLFISA
ATVPPGGLLSGPGLATAASSAVSAAPSAQTHRPFLGTFAPGPQFALGPMSLQANLGSSVL
QSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGN
NT seq
4815 nt
NT seq
+upstream
nt +downstream
nt
atggcgggtgtggacctagagggccaagggctgagtggacaggcccgctcggtgatgggc
ctggaagcctccgcagagctgccccagttgtcttctgacatttaccaggaggtcttgggg
ccactagttcccatcagtggtccccaccccaagtttctgagtcggctgtgtgccgatgct
gcagaattcttcacctgctgtgaaatcctgcagggggcagggcgtggatacgccctctcc
gtggtgcagcagctgcagcactcaccctgcatcaccggagggtgtaaatcctgtcccttt
gtctttcaggacaaacaccacgatgctgctcatgaaatcatcgagaccatccgatgggtc
tgtgaagagatcccagacctcaagcttgctatggagaattacgttctgatcgactacgac
accaaaagcttcgaaagcatgcagaggctctgtgacaaatacaaccgtgccatcgacagc
atccaccagctgtggaaggggaccacgcagcccatgaaactgaacactcggccgtccaac
gggctcctgcggcacatcctgcagcaggtctacaaccactcggtgacagaccccgagaag
ctcaacaactacgagcccttctcccccgaagtgtacggggagacctcctttgacttggtc
gcacagatgatcgacgagatcaagatgaccgaggatgacctgtttgtggacctgggcagt
ggagtgggccaggtcgtgctgcaggtcgccgcggccaccaactgcaaacatcactatggc
gtagagaaagctgacatcccagccaagtacgcggagaccatggaccgagagttcaggaag
tggatgaaatggtatggaaaaaagcatgcagaatacacactggaaagaggcgacttcctc
tcggaagagtggagagagcggattgccaacacaagtgttatatttgtgaataattttgcc
tttggtcctgaggtggatcaccagctgaaggagcggtttgcgaacatgaaggaaggtggc
agaatcgtgtcctcgaagccctttgcgcctctgaacttcagaataaacagcagaaacttg
agtgacatcgggaccatcatgcgcgtggtggagctctcgcccctgaaaggctcggtgtcc
tggacggggaagccagtctcctactacctgcacaccatcgaccgcaccatacttgaaaac
tatttttctagtctgaaaaatccaaaactcagggaggagcaggaagcggcccggcgccgg
cagcagcgagacaacaagagcaccacggccactcccaccaagctgcccgagagcaaggcc
gccgtgcccgcggacaccccgatggattccggggccgaggaagaaaaagctggggcgacc
accatcaaaaagccgtcaccctccaaagcccggaagaaaaagctgaacaagaaggggcgg
aagatggctggccggaagcgcgggcgtcccaagaagatgagcaccgcgaacccggagcgt
aagcccaagaagagccaaactgcactggacctcctgcacgcccaggccgcgtcgcagacg
gcagcgccctcgccgcaggatgcgtacaagtcacctcatagcccgttttaccagctacct
cccagtgtgcagcggcagccccccgaccagctgctgctggcacccaccccgcccgcactg
cagaagctgctagaatccttcaagattcagtacttgcagttcttggcgtacaccaagacc
gcccagtacaaggccagcctgcagcagctgctggaccaggagaaggagaagaacacccgg
ttgctaggtgctgcgcagcagctgttcggccactgccaggcccagaaagaggagatcaag
aggctcttccagcagaaactggatgagctgggcgtgaaggcgctgacctacaacgacctg
atccaagcgcagaaggagatttcggctcacaaccagcagctgagggaacagacggagcag
ctgcagaaggacaacagggagctgagaagccagagcctgcagctgctcaaggctcggtgt
gaggagctgaagctggactggtccacgctgtcgctggagaacttgctgaaggagaagcag
gccctgaggacccagatctccgagaagcagaggcactgcctggagctgcagatcagcatc
gtggaactggagaagagccagcggcagcaggagctcctgcagctcaagtcttgcgtgcca
ccggatgatgccctgtcggcgcacctgcgcgggaaaggcgccctgggccgggagctggag
gccgaccccagccggctgcatcttgacctggactgctccaagttctccctgccccacttg
agcagcgcaagcccagaactctccatgaatggccacgcggctagctacgaggtgtgcggc
acgctgagccggccctcgtccaagcagaacactccccagtacctggcctccccgctggac
caggaagtcataccctgcacccccagtcacagcagccggccgaggctcgagaagatgtcg
ggcctggccttgcccgactacacccggctctccccagccaagctggtgctgaggcggcac
ctgagccaggaccacgtggccagtggcaaaacagcggccagcgagctgcacccgcgagct
gagcacgccaaggagaacggccttccgtaccagagccctggcattgcaaacggcatcaag
ctgagccctcaggaccctcgaccctcatcccccatggccttacagatgacaggggagagg
ggcggcgagaagggtgtgaaggagcgcagctatgccagcagtggggaggccatcaccagc
ctgcccgtcagcatcccgctcagcactgtgcagccgagcaagctgcccgtcagcatccct
ctggccagcgtggtgctgcccagccgcgccgagaaagtgaggagcacccccagccctgtg
ccgcagacccgagagtcctcgtccacacttgaaaagcagatgggcgctaatgcccacggc
gttgcaagcaaaggcctcacccctgctcccgcaggcttctacgcgggctcagtggctgtc
agcggggccctggcaggcagcccggcccccctcgctcccggaactgagcccggcgccttc
gatgaggtctcgggctcaggaagcctgttcgccagcatggggccctgctccaccccgcag
cacccgcccctgctgccgcagtcccgcggctccggagcagcctcgcctgcccatccgctc
tgcgccagcccccggctcagcagtgccgcccagggcccactccccgaggccaacaaaggg
gaccttccttccgaggccggcttttcagatcccgagggcgaagccaagaggaggatcgtc
tttaccatctcggctggcggcagtgccaaacagtcgcctcccggcaaacccagccctctg
cccacgggcgcccgcggggacagtggccagggccatgggccggacagccgcaagcggggc
aggaggaagcgggcggcggctgggacccccagcttgagctccggcgtgtcgcccaagcgt
cgggccctgccgtctgttgccggccttttcacgcagtcttcagggtccccgctgaacctc
aactccatggtcagcaacattaaccagcctttggaaatcacggccatctcgtcccccgag
agcctgaagagctcccctgtcccttaccaggacaacgaccagccgcccgtcctcaagaag
gagaagccgttgagccagaccaacggggcccactactccccactgacctcagacgaggag
cagggctccgaggacgagccaggcagcgccagaatcgagagaaaaattgcaacaatctcc
ttagaaagcaaatctcctccaaaaaacttggaaagcggtggtggcctggccgggaggaag
ccgacccctgccagcgagcctgccaacagcagcaagtggaaatccaccttctcacccatt
tccgacctcggcctggccaagtgcgccgacagcccgctgcaggccggctccgccctgagc
cagaactccctgttcgctttccggccccccctagaggagcccggcttggctgaagccaag
ctggctgcccaccccaggaaaagcttttccggtgccctgtcgggggccggtgggctgagc
cccagcagcaaccctcccaatggcttcgccttcagcgggggcctggccgccgacctcagt
ttacacagcttcagcgatggtgcttctctctcccacaaggtccccgaggcggccagcctg
ggtgcccccctgagcttccctgccccgcggggcaaggagggcagtgccgcagagtccggc
gcctttgtgaacaagaggcagctggaaggactgggtggccccaagggcagggaggccggc
gagctgggcctgccggcgtgcgggcccccggacaagccctcgctggtgcacagcaagccg
ggcaagggccgggaccgcgagcccgacttgaagaatggccacaacctcttcatttctgcc
gccactgtgcctcccgggggcctcctcagcggcccgggcctcgccacggcggcgtcctcg
gcagtcagcgcggccccctccgcccagacacaccgccccttcctgggcacctttgccccc
ggcccacagttcgccctgggtcccatgtccctgcaggccaacctgggctcgtccgtgctc
cagtccttgttcagctccgtgccggccgccgccggcctggtgcacgtctcgtccgctgca
accagactgaccaactcgcacgccatgggcagcttttcctccggggtggcaggcggcgca
gttggaggtaattag
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