Neogale vison (American mink): 122909778 Help Entry 122909778         CDS       T08764                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism nvs  Neogale vison (American mink) Pathway nvs04010   MAPK signaling pathway nvs04014   Ras signaling pathway nvs04015   Rap1 signaling pathway nvs04022   cGMP-PKG signaling pathway nvs04066   HIF-1 signaling pathway nvs04068   FoxO signaling pathway nvs04072   Phospholipase D signaling pathway nvs04150   mTOR signaling pathway nvs04151   PI3K-Akt signaling pathway nvs04152   AMPK signaling pathway nvs04211   Longevity regulating pathway nvs04213   Longevity regulating pathway - multiple species nvs04520   Adherens junction nvs04910   Insulin signaling pathway nvs04913   Ovarian steroidogenesis nvs04923   Regulation of lipolysis in adipocytes nvs04930   Type II diabetes mellitus nvs04931   Insulin resistance nvs04932   Non-alcoholic fatty liver disease nvs04960   Aldosterone-regulated sodium reabsorption nvs05010   Alzheimer disease nvs05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:nvs00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     122909778 (INSR)    04014 Ras signaling pathway     122909778 (INSR)    04015 Rap1 signaling pathway     122909778 (INSR)    04066 HIF-1 signaling pathway     122909778 (INSR)    04068 FoxO signaling pathway     122909778 (INSR)    04072 Phospholipase D signaling pathway     122909778 (INSR)    04022 cGMP-PKG signaling pathway     122909778 (INSR)    04151 PI3K-Akt signaling pathway     122909778 (INSR)    04152 AMPK signaling pathway     122909778 (INSR)    04150 mTOR signaling pathway     122909778 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     122909778 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122909778 (INSR)    04923 Regulation of lipolysis in adipocytes     122909778 (INSR)    04913 Ovarian steroidogenesis     122909778 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     122909778 (INSR)   09149 Aging    04211 Longevity regulating pathway     122909778 (INSR)    04213 Longevity regulating pathway - multiple species     122909778 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     122909778 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     122909778 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122909778 (INSR)    04932 Non-alcoholic fatty liver disease     122909778 (INSR)    04931 Insulin resistance     122909778 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:nvs01001]     122909778 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:nvs04090]     122909778 (INSR) Enzymes [BR:nvs01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      122909778 (INSR) Protein kinases [BR:nvs01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    122909778 (INSR) CD molecules [BR:nvs04090]  Proteins   122909778 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  122909778 NCBI-ProteinID:  XP_044110239 LinkDB All DBs Position 6:complement(218378543..218507143) Genome browser AA seq 1369 aa AA seqDB search MGAGAGRGAATAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLSTIDWSRILDSVEDNYVVLNKDDNE ECGDICPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFEAEGSPKHNQSEHEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRPSRKRRALRDVANVTAAVPTAPGFPNTSTSTPTSPE AHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVSARTMPEAKADDI VGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRL RGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIG SIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGS FGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVV SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAK KFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVF TTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCW QFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRAS HSQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNPS NT seq 4110 nt NT seq  +upstreamnt  +downstreamnt atgggcgccggggctgggcggggggcggcgactgcgccgctgctggtggcggtggccgcg ctgctgctgggtgccgcgggccacctgtacccgggagaggtgtgtcccggcatggatatc cggaacaacctcacgaggttgcacgagctggccaactgctcggtcattgaaggacatttg cagatactgttgatgttcaaaacgaggcccgaggatttccgcgacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctcgcgcctcttcttcaactacgcactg gtcatcttcgagatggttcacctgaaggaactcggcctctatagcttgatgaacattacc cggggctccgtccgcatcgagaagaataacgagctgtgctacctgtccaccatcgactgg tcgcgcatcctggattctgtggaggataattacgtcgtgctgaacaaagacgacaacgag gagtgtggggacatttgtccgggcacggcgaagggcaagaccagctgccctgccactgtc atcaacgggcagtttgtcgagcgctgttggacacacagccactgccagaaagtttgtccc accatctgcaagtcacacggctgcacctcggagggcctctgctgccacagcgagtgcttg ggcaattgctccgagcccgatgaccccaccaagtgcgtggcctgtcgcaacttctacttg gacggcaggtgcgtggagacctgcccgcccccatactaccacttccaggactggcgctgc gtgaacttcagcttttgccaggacctgcacaacaaatgcaagaactcccggaggcagggc tgccaccagtacgtcattcacaacaacaagtgcatccccgagtgcccctctggttacacg atgaattccagcaacctgatgtgcactccatgcctgggcccctgtcccaaggtctgccac atcctggaaggcgagaagaccattgactcggtgacgtctgcccaggagcttcgaggctgc actgtggtcaacggaagcctcatcatcaacatccgagggggcaacaacctggcagctgag ctggaggcgaacctcggactcattgaggaaatttctgggtatctgaaaatccggagatcc tacgctcttgtgtcactttcctttttccggaagttacggctgattcgaggagagaccttg gaaatcgggaactactctttctacgccttggacaaccagaacctaaggcagctttgggac tggagcaaacacaacctcaccatcactcagggaaaactcttcttccactataatcccaaa ctctgcttgtcagaaattcacaagatggaggaagtttcgggaaccaaggggcgccaggag aggaacgacattgccctgaagaccaacggggaccaggcgtcttgtgagaatgaactcctt aaattttcttacattcggacatcgtacgacaagatcttgctgaaatgggagccatactgg ccccctgacttccgagacctcttggggttcatgcttttctacaaagaggccccttaccag aatgtgaccgagttcgacgggcaggacgcgtgtggctccaacagctggaccgtggtggac attgacccccctctgcggtccaatgaccccaagtcgcagaaccacccagggtggctgatg cggggtctcaagccctggacccagtacgccatttttgtcaagaccttggttaccttttct gatgaacgccgcacatacggggccaagagtgacatcatctatgtgcagacagatgccact aacccttccgtccccctggatccaatctccgtttctaattcctcgtcccagattatcctg aagtggaaacctccctcggaccccaacggcaacatcacacactacctggttttctgggag aggcaggcagaagacagtgagctgtacgagctggattattgcctcaaagggttgaagctg ccgtcccggacctggtctccgccgttcgaggctgagggctccccgaagcacaaccagagt gaacacgaggagtccgccggcgagtgctgctcctgccccaagacagactcccagatcctc aaggagctggaggagtcctcttttaggaagacctttgaggattacctgcacaatgtggtc ttcgtccccaggccgtcgcggaaacgcagggccctcagggacgttgccaacgtgacagcg gccgtgcccaccgctccaggtttccccaacacctcgactagcacgcccacgagcccggag gcgcacaagccttttgagaaggtggtgaacaaggagtccctggtcatctctgggctgcgt catttcacgggctaccgtatcgagctgcaggcttgcaaccaggacgcccccgaggagagg tgcagcgtggcggcctacgtcagcgccaggaccatgcccgaagccaaggcagacgacatc gttggccccgtgacccacgaaatcttcgagaacaatgtcgttcacttgatgtggcaggag ccgaaggaacccaacggtctgattgtgctgtatgaagtgagttaccgacgctatggagat gaggagctgcacctctgtgtctcccgcagacacttcgctctggagcggggctgcaggctg cgcgggctgccgccggggaattacagcgtgcgagtccgggccacctccctggcaggcaac ggctcctggacagaagccacctatttctacgtgacagactatttagatgtcccatcgaat attgcaaaaatcatcatcggccccctcatctttgtctttctcttcagtgttgtgattgga agtatttacctgttcctgcggaagaggcagccggatgggccgctgggaccactgtatgcg tcttcaaaccctgagtacctcagtgccagtgatgtgtttccatgttctgtgtatgtgccg gacgagtgggaggtgcctcgggagaagatcactctcctgcgggagctggggcagggctcc ttcggcatggtgtacgagggcaacgccagggacatcgtcaagggcgaggcggagacccgc gtggcggtgaagacggtcaacgagtcggccagtctgcgggagaggatcgagtttctcaac gaggcctcagtcatgaagggcttcacctgtcatcacgtggtccgcctcctgggggtggtg tccaaaggccagccaacactggtggtgatggagctgatggcccacggagacctcaagagc tacctccgctccctgcggccggaggctgagaataaccccggccgccctccccctaccctg caagagatgattcagatggcagcggagatcgccgacgggatggcctacctgaatgccaag aagttcgtgcaccgggatcttgcagcccggaactgcatggtggcccacgatttcaccgtc aaaattggagactttgggatgaccagagacatctatgaaacggattactaccggaaagga ggcaagggtctgctccctgtgcggtggatggcaccggaatccctgaaggacggggtcttt accacttcttctgacatgtggtcctttggcgtggtcctttgggaaatcaccagcttggca gaacagccttaccaaggcctgtcgaatgaacaggtgttgaaatttgtcatggatggaggg tatctggaccaacccgacaattgtccagagagagtcaccgacctgatgcgtatgtgctgg caattcaatcccaagatgcggcccaccttcctggagatcgtcgacctgctcaaggacgac ctgcaccccagcttcccggaagtttccttcttccacagcgaggagaacaaggcgcctgag agcgaggagctggagatggagtttgaggacatggagagtgtccccctggatcgggcctcc cactctcagagggaggaggccgggggccgggatggagggtcctccctgggcctaaagcgg aactatgaggagcacatcccctatacccacatgaatgggggcaagaaaaacggacggatt ctgactctgccgaggtcgaatccttcctaa

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