KEGG   Ornithorhynchus anatinus (platypus): 100092264
Entry
100092264         CDS       T01045                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa01522  Endocrine resistance
oaa04010  MAPK signaling pathway
oaa04015  Rap1 signaling pathway
oaa04068  FoxO signaling pathway
oaa04071  Sphingolipid signaling pathway
oaa04114  Oocyte meiosis
oaa04148  Efferocytosis
oaa04218  Cellular senescence
oaa04261  Adrenergic signaling in cardiomyocytes
oaa04370  VEGF signaling pathway
oaa04380  Osteoclast differentiation
oaa04550  Signaling pathways regulating pluripotency of stem cells
oaa04611  Platelet activation
oaa04613  Neutrophil extracellular trap formation
oaa04620  Toll-like receptor signaling pathway
oaa04621  NOD-like receptor signaling pathway
oaa04622  RIG-I-like receptor signaling pathway
oaa04625  C-type lectin receptor signaling pathway
oaa04657  IL-17 signaling pathway
oaa04658  Th1 and Th2 cell differentiation
oaa04659  Th17 cell differentiation
oaa04660  T cell receptor signaling pathway
oaa04664  Fc epsilon RI signaling pathway
oaa04668  TNF signaling pathway
oaa04670  Leukocyte transendothelial migration
oaa04714  Thermogenesis
oaa04722  Neurotrophin signaling pathway
oaa04723  Retrograde endocannabinoid signaling
oaa04728  Dopaminergic synapse
oaa04750  Inflammatory mediator regulation of TRP channels
oaa04912  GnRH signaling pathway
oaa04914  Progesterone-mediated oocyte maturation
oaa04917  Prolactin signaling pathway
oaa04926  Relaxin signaling pathway
oaa04932  Non-alcoholic fatty liver disease
oaa04933  AGE-RAGE signaling pathway in diabetic complications
oaa04935  Growth hormone synthesis, secretion and action
oaa04936  Alcoholic liver disease
oaa05014  Amyotrophic lateral sclerosis
oaa05020  Prion disease
oaa05022  Pathways of neurodegeneration - multiple diseases
oaa05132  Salmonella infection
oaa05133  Pertussis
oaa05135  Yersinia infection
oaa05140  Leishmaniasis
oaa05142  Chagas disease
oaa05145  Toxoplasmosis
oaa05152  Tuberculosis
oaa05161  Hepatitis B
oaa05163  Human cytomegalovirus infection
oaa05167  Kaposi sarcoma-associated herpesvirus infection
oaa05169  Epstein-Barr virus infection
oaa05170  Human immunodeficiency virus 1 infection
oaa05171  Coronavirus disease - COVID-19
oaa05205  Proteoglycans in cancer
oaa05208  Chemical carcinogenesis - reactive oxygen species
oaa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oaa05415  Diabetic cardiomyopathy
oaa05417  Lipid and atherosclerosis
oaa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100092264 (MAPK14)
   04015 Rap1 signaling pathway
    100092264 (MAPK14)
   04370 VEGF signaling pathway
    100092264 (MAPK14)
   04668 TNF signaling pathway
    100092264 (MAPK14)
   04068 FoxO signaling pathway
    100092264 (MAPK14)
   04071 Sphingolipid signaling pathway
    100092264 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100092264 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100092264 (MAPK14)
   04218 Cellular senescence
    100092264 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100092264 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100092264 (MAPK14)
   04613 Neutrophil extracellular trap formation
    100092264 (MAPK14)
   04620 Toll-like receptor signaling pathway
    100092264 (MAPK14)
   04621 NOD-like receptor signaling pathway
    100092264 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    100092264 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    100092264 (MAPK14)
   04660 T cell receptor signaling pathway
    100092264 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    100092264 (MAPK14)
   04659 Th17 cell differentiation
    100092264 (MAPK14)
   04657 IL-17 signaling pathway
    100092264 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    100092264 (MAPK14)
   04670 Leukocyte transendothelial migration
    100092264 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100092264 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    100092264 (MAPK14)
   04917 Prolactin signaling pathway
    100092264 (MAPK14)
   04926 Relaxin signaling pathway
    100092264 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    100092264 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100092264 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    100092264 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    100092264 (MAPK14)
   04722 Neurotrophin signaling pathway
    100092264 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100092264 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100092264 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    100092264 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100092264 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    100092264 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100092264 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100092264 (MAPK14)
   05161 Hepatitis B
    100092264 (MAPK14)
   05171 Coronavirus disease - COVID-19
    100092264 (MAPK14)
   05163 Human cytomegalovirus infection
    100092264 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100092264 (MAPK14)
   05169 Epstein-Barr virus infection
    100092264 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100092264 (MAPK14)
   05135 Yersinia infection
    100092264 (MAPK14)
   05133 Pertussis
    100092264 (MAPK14)
   05152 Tuberculosis
    100092264 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100092264 (MAPK14)
   05140 Leishmaniasis
    100092264 (MAPK14)
   05142 Chagas disease
    100092264 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100092264 (MAPK14)
   05020 Prion disease
    100092264 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    100092264 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100092264 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    100092264 (MAPK14)
   05415 Diabetic cardiomyopathy
    100092264 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100092264 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    100092264 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100092264 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100092264 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oaa01001]
    100092264 (MAPK14)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100092264 (MAPK14)
Protein kinases [BR:oaa01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100092264 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH
Other DBs
NCBI-GeneID: 100092264
NCBI-ProteinID: XP_028924496
Ensembl: ENSOANG00000042195
LinkDB
Position
7:68660388..68748660
AA seq 360 aa
MSEERPKFYRQELNKTLWEVPERYQNLSPVGSGAYGSVCSSYDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHSYFAQYHDPDDEPVADPYDQSFESRELLIEEWKSLTYDEVVSFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctgaggagaggcccaagttctaccggcaggagctcaacaagacgctgtgggaggtg
cccgagcgctatcagaacttgtccccggtgggctcgggggcctacggctccgtgtgttct
tcctatgacacaaaaaccggactccgagtggcagttaagaagctgtccaggccgtttcag
tctatcatccacgccaaaaggacgtatcgagaactacgtctccttaagcacatgaaacac
gaaaacgtgattggtctcttggatgtgttcacacctgcaaagtccctggaggagtttaac
gatgtatacctggtgacgcatctcatgggagcagatctgaacaacattgtgaaatgtcaa
aaacttacagatgaccatgtacagttcctcatttatcagattctccgtggcctgaagtac
attcattcagctgacatcatacacagagatctaaaacctagcaatctagctgtaaatgaa
gactgtgagctgaagatcttagattttggcctggcccggcacactgatgacgagatgaca
ggttacgtggccaccaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccaaacagttgatatttggtcagtgggctgcataatggccgagcttttgactggaaga
acgttgtttccgggaacagaccatattgatcagttgaagctcattttgagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgccagaaactacattcag
tctttgactcaaatgccgaagatgaacttcgcaaatgtgtttatcggtgccaatcccctc
gcggtcgacttgctggaaaagatgctggtgctggactccgataagaggatcacggcggcc
caagccctagcccacagctacttcgctcagtatcacgaccctgacgacgagcccgtcgcc
gatccctacgatcagtcctttgagagccgggagctcctgatagaggaatggaaaagcctg
acctacgatgaagtcgtcagctttgtgcctccgccgctcgaccaagaagagatggagtcc
tga

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