Oryctolagus cuniculus (rabbit): 100008911 Help Entry 100008911         CDS       T03373                                  Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu04010   MAPK signaling pathway ocu04014   Ras signaling pathway ocu04015   Rap1 signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04066   HIF-1 signaling pathway ocu04068   FoxO signaling pathway ocu04072   Phospholipase D signaling pathway ocu04150   mTOR signaling pathway ocu04151   PI3K-Akt signaling pathway ocu04152   AMPK signaling pathway ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04520   Adherens junction ocu04910   Insulin signaling pathway ocu04913   Ovarian steroidogenesis ocu04923   Regulation of lipolysis in adipocytes ocu04930   Type II diabetes mellitus ocu04931   Insulin resistance ocu04932   Non-alcoholic fatty liver disease ocu04960   Aldosterone-regulated sodium reabsorption ocu05010   Alzheimer disease ocu05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100008911    04014 Ras signaling pathway     100008911    04015 Rap1 signaling pathway     100008911    04066 HIF-1 signaling pathway     100008911    04068 FoxO signaling pathway     100008911    04072 Phospholipase D signaling pathway     100008911    04022 cGMP-PKG signaling pathway     100008911    04151 PI3K-Akt signaling pathway     100008911    04152 AMPK signaling pathway     100008911    04150 mTOR signaling pathway     100008911  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     100008911  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100008911    04923 Regulation of lipolysis in adipocytes     100008911    04913 Ovarian steroidogenesis     100008911   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100008911   09149 Aging    04211 Longevity regulating pathway     100008911    04213 Longevity regulating pathway - multiple species     100008911  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100008911   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100008911   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100008911    04932 Non-alcoholic fatty liver disease     100008911    04931 Insulin resistance     100008911  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ocu01001]     100008911   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:ocu04090]     100008911 Enzymes [BR:ocu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      100008911 Protein kinases [BR:ocu01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    100008911 CD molecules [BR:ocu04090]  Proteins   100008911 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  100008911 NCBI-ProteinID:  XP_008247399 Ensembl:  ENSOCUG00000004436 LinkDB All DBs Position Unknown AA seq 1381 aa AA seqDB search MGAGGRRGAVAAPLLAAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKEVGLHSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCTVCRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLDGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTISQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSSIRTTFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKAQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQILLKWKPPSDPNGNITHYLVFWE RQEEDRELYELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYEDSAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKTSSGSGAENTRPSRKRRSLGEVNNVTAAAPTVPGF SNTTSTSVPVSPEVHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKDPNGLIVLYEVSYRRYGDEELHLCV SRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVSLLKDDLHPSFPEVSFFHSEENKAPESEDLEME FEDMESVPLDRSAHCQREEAGGREGVSSLGVKRYEDHIPYTHMNGGKKNGRILSLPRANP S NT seq 4146 nt NT seq  +upstreamnt  +downstreamnt atgggcgctgggggccggcggggggcggtggccgcgccgctgctggcggcggtggccgcg ctgctggtgggcgccgcgggccacctgtaccccggagaggtgtgtcccggcatggatatc cggaacaacctcaccagactgcatgagctggagaactgctctgtcatcgagggccacctg cagatcctcctgatgttcaagacgaggcctgaggacttccgggacctcagcttccccaag ctcatcatgatcaccgactacctgctgctgttccgggtctacgggctggagagcctcaag gacctgttccccaacctcacggtcatccggggctccaggctgttcttcaactatgcgctg gtcatcttcgagatggtgcacctgaaggaggttgggctacacagcctcatgaacatcacc cggggctccgtgcgcatcgagaagaacaatgaactctgctacttggccaccatagactgg tcccggatcctggactcagtggaggacaactacattgtgctgaacaaggacgacaacgag gagtgcggggacatctgtccaggcaccgcaaagggcaagaccaactgtcctgccactgtc atcaatgggcagtttgtcgagcggtgctggactcacagccactgccagaaagtgtgcccg accatctgtaagtcgcacggctgcaccgccgagggcctctgctgccacagcgagtgcttg ggcaactgttccgagcccgacgaccccaccaagtgcaccgtgtgccggaacttctacctg gatggccggtgcgtggagacctgcccgcccccctactaccacttccaggactggcgctgc gtgaacttcagcttctgccaggacctgcacaacaagtgcaagaactcgcgcaggcagggc tgccaccagtacgtcatccacaacaacaagtgcatccccgagtgcccctcggggtacacg atgaactccagcaacttgatgtgcaccccgtgcctgggcccctgtcccaaggtgtgccac ctgctagatggtgagaagaccatcgactcggtgacgtctgcccaggagctccgaggctgc accgtcatcaacggcagcctgatcatcaacatccgaggaggcaataacctggcggctgag ctcgaggccaacctcggcctcattgaagagatttcagggtacctgaaaatccgccgatcc tacgctctggtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg gagattggaaactactccttctacgccttggacaaccagaacctgaggcagctctgggac tggagcaaacacaacctcaccatctctcaggggaagctcttcttccactacaaccccaaa ctctgcttgtcagagattcacaagatggaagaagtctccggaaccaaggggcgccaggag aggaacgacatcgccctgaaaaccaacggggaccaggcttcctgtgaaaacgagctgctt aagttttcttccattcggacaacgttcgacaagatcttgctgagatgggagccctactgg ccccccgacttccgagacctcttggggttcatgcttttttacaaagaggccccctatcag aacgtgacggagttcgatgggcaggacgcgtgtggctccaacagctggaccgtggtagac atcgacccgcccctgagatccaatgaccccaaggctcagaaccaccctgggtggctgatg cgcggcctcaagccctggacccagtatgccatcttcgtgaagacattggtcaccttctct gatgagcgccggacctatggagccaagagtgacatcatttatgtccagacggacgctacc aatccttctgtccccctggatccgatttcggtttctaactcctcctcccagattcttttg aagtggaaacctccctcggaccccaatggcaacatcacgcactacctggttttctgggag agacaggaggaggacagagagctctacgagttggattattgcctcaaagggttgaagctg ccctcccgcacgtggtcacccccattcgaatccgacgattcgcagaagcacaaccagagt gaatatgaggactcggcgggcgagtgctgctcctgccccaagaccgactcccagatcctg aaggagctggaggagtcttccttccgcaagactttcgaggactacctgcacaacgtggtc ttcgtgcccagaaaaacctcttcaggctctggtgccgagaacactaggccgtcgaggaaa cgcaggtcccttggtgaggtcaacaatgtgacagcggctgcacccacagtcccaggattc tccaacacgacgtccaccagcgtgcccgtgagcccagaggtgcacaggcccttcgagaag gtggtgaacaaagagtcactggtcatctccggcctgcgccacttcaccggctaccgcatc gagctgcaggcctgcaaccaggacacgcccgaggagaggtgcagcgtggctgcctacgtc agtgcacggaccatgcctgaagccaaggctgatgacatcgtcggccccgtgacgcatgag atcttcgagaacaacgtggtccatttgatgtggcaagagccgaaggaccccaacggtctg atcgtcctgtacgaagtgagctatcggagatatggtgatgaggagctgcacctctgcgtc tcccgcaagcactttgccctggagcggggctgcaggctgcgggggctttcccccggaaac tacagcgtgcgggtgcgggccacctccctggcaggcaatggctcctggacggaagccacc tatttctacgtgacagactacctagatgtcccatcgaatattgcaaaaatcatcatcggc cccctcatcttcgtcttcctcttcagtgtggtgattggaagtatttatctattcctgaga aagaggcagccggatgggccactgggaccgctgtacgcttcctcaaaccccgagtacctc agcgccagtgatgtgtttccctgttctgtgtacgttccggatgaatgggaggtgcctcgg gagaagatcaccctcctgcgggagctgggccagggctcctttggcatggtgtatgagggc aacgccaaggacatcatcaagggggaggccgagacccgcgtggctgtgaagactgtcaat gagtcggccagtctccgggagcggattgagttcctcaatgaggcctccgtcatgaagggc ttcacctgccatcatgtggtccgcctcctgggggtggtgtccaagggccagcccacgctg gtggtgatggagttgatggctcacggagacttgaagagctaccttcgttctctgcggccc gaggctgagaacaacccgggtcgccctccccctaccctccaagagatgatacagatggcg gcggagatcgcggacggcatggcgtacctgaacgccaagaagtttgtgcaccgggacctg gcagcccgaaactgcatggttgcccacgattttaccgtcaaaatcggagatttcggaatg accagagacatctacgaaacggattactaccggaaggggggcaagggtctgctgcctgtg cgatggatggcgccagagtccctgaaggacggggttttcaccacctcttctgacatgtgg tcgtttggcgtggtcctctgggaaatcaccagcttggcggagcagccttaccaaggcctg tccaatgagcaggtgttgaagtttgtcatggacggagggtacctggaccaacccgacaac tgtccagagagagtcaccgacctgatgcgcatgtgctggcagttcaaccccaagatgcgg cccactttcctggagatcgtcagcctgctgaaggacgacctccaccccagctttccggaa gtttccttcttccacagcgaggagaacaaggctcccgagagcgaggacctggagatggaa ttcgaggacatggagagcgtgccactggaccggtccgcgcactgtcagagagaggaggca gggggccgggaaggggtgtcctcgctgggcgtcaagcgctatgaagaccacatcccctac acccacatgaacgggggcaagaaaaacgggcggattctgagcctgcctcgggcgaatccc tcctaa

DBGET integrated database retrieval system