Oryx dammah (scimitar-horned oryx): 120863920 Help Entry 120863920         CDS       T07255                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism oda  Oryx dammah (scimitar-horned oryx) Pathway oda04010   MAPK signaling pathway oda04014   Ras signaling pathway oda04015   Rap1 signaling pathway oda04022   cGMP-PKG signaling pathway oda04066   HIF-1 signaling pathway oda04068   FoxO signaling pathway oda04072   Phospholipase D signaling pathway oda04150   mTOR signaling pathway oda04151   PI3K-Akt signaling pathway oda04152   AMPK signaling pathway oda04211   Longevity regulating pathway oda04213   Longevity regulating pathway - multiple species oda04520   Adherens junction oda04910   Insulin signaling pathway oda04913   Ovarian steroidogenesis oda04923   Regulation of lipolysis in adipocytes oda04930   Type II diabetes mellitus oda04931   Insulin resistance oda04932   Non-alcoholic fatty liver disease oda04960   Aldosterone-regulated sodium reabsorption oda05010   Alzheimer disease oda05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:oda00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     120863920 (INSR)    04014 Ras signaling pathway     120863920 (INSR)    04015 Rap1 signaling pathway     120863920 (INSR)    04066 HIF-1 signaling pathway     120863920 (INSR)    04068 FoxO signaling pathway     120863920 (INSR)    04072 Phospholipase D signaling pathway     120863920 (INSR)    04022 cGMP-PKG signaling pathway     120863920 (INSR)    04151 PI3K-Akt signaling pathway     120863920 (INSR)    04152 AMPK signaling pathway     120863920 (INSR)    04150 mTOR signaling pathway     120863920 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     120863920 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     120863920 (INSR)    04923 Regulation of lipolysis in adipocytes     120863920 (INSR)    04913 Ovarian steroidogenesis     120863920 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     120863920 (INSR)   09149 Aging    04211 Longevity regulating pathway     120863920 (INSR)    04213 Longevity regulating pathway - multiple species     120863920 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     120863920 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     120863920 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     120863920 (INSR)    04932 Non-alcoholic fatty liver disease     120863920 (INSR)    04931 Insulin resistance     120863920 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oda01001]     120863920 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:oda04090]     120863920 (INSR) Enzymes [BR:oda01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      120863920 (INSR) Protein kinases [BR:oda01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    120863920 (INSR) CD molecules [BR:oda04090]  Proteins   120863920 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  120863920 NCBI-ProteinID:  XP_040096538 LinkDB All DBs Position Unknown AA seq 1382 aa AA seqDB search MGAGGGRGAAAVLLMVVVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCVPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPSRKRRALGDVGNVTAAVPTVLGF PNSSSTSIPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV SRRHYALERGCRLRGLLPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSICLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMESVPLDRSSHAQREEAGGRDGGSALGLKRNYDEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggcgggaggggggcggcagccgtgctgctgatggtggtcgtcgccgcg ctgctggtgggcgccgctggccacctgtaccctggagaagtgtgccccggtatggatatc cggaataatctcacccggctgcatgagctggccaactgctcggtcattgaaggacatttg cagattctgttgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag gacttgttccccaacctcacggtcatccgaggctcacgcctcttctttaattatgcactg gtcatctttgagatggttcacctgaaggagcttggcctctacaacctgatgaacatcacc cgggggtctgtccgcatcgagaagaacaatgaactctgctacctggccaccatcgactgg tctcgcatcctggattccgtggaggataattacatcgtgctgaacaaagacgacaatgag gagtgtggggacatttgtccaggcaccgccaagggcaagaccaactgccctgccactgtc atcaacgggcaatttgtggagcggtgctggacacacagccactgccagaaagtgtgtccg actatctgtaagtcacatggctgcacctctgagggtctctgctgccacagcgagtgcttg ggcaactgctcagagcccgacgaccccaccaagtgcgtggcgtgtcgcaacttctacctg gacggcaggtgcgtggagacctgcccgcccccttactaccacttccaagactggcgctgc gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcaaggc tgccaccagtatgtcattcacaataacaagtgcgtccctgagtgcccctctggctacacg atgaattctagcaacttgatgtgtaccccttgcctgggcccctgtcccaaggtatgccac ctcctggaaggtgagaagaccatcgattcggtgacatctgcccaggagctccgaggctgc accatcgtcaacggaagcttaatcatcaatattcgagggggcaacaacctggcagctgag ctagaggccaaccttggactcattgaagaaatttcaggatatctgaaaatccgccggtcc tatgccctggtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg gaaattgggaactactctttctacgccttggacaaccagaacctaaggcagctatgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa ctctgcctgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag agaaatgacattgctctgaagaccaatggggaccaggcatcctgtgaaaatgaattactt aaattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtattgg cctcctgacttccgagacctcctggggttcatgttgttctacaaagaggccccttaccag aacgtgacagaattcgatgggcaggatgcctgtggctccaacagctggacagtggtggat attgacccgcctacgaggtccaacgatcccaagtcacagaaccaccctgggtggctgatg cgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtcaccttttct gatgaacgccgtacatacggagccaagagtgacatcatctatgtccagacagatgccact aatccttccgtccccctggatcccatctcagtttccaattcctcgtcccagattatcctg aagtggaagcctccctccgaccccaacggcaatatcacacactacttggtgttctgggag aggcaggcggaagacagtgagctgtatgaactggattattgcctcaaagggttgaagctg ccctcccggacctggtctccaccgtttgagtcagaggggtcccagaagcacaaccagagt gagtatgaggagtctgctggcgaatgctgctcctgcccgaagaccgactctcagatcctc aaggagctggaggagtcctcgttcaggaaaacgtttgaagattacctgcacaacgtggtt ttcatccccagaaaatcatcttcaggccctgttgccgaggacgctaggccttcgaggaaa cgcagagcccttggtgacgtggggaatgtaacagcagccgtgcccaccgttctggggttc cccaatagctcctctaccagcatacccacgagctcggaggagcacagacccttcgagaaa gtggtgaacaaggagtcgctggtcatctccggcctacgtcactttactggctatcgcatc gagctacaggcttgcaaccaagattcccccgaggagaggtgtagcgtggctgcctatgtc agcgccaggaccatgcctgaagccaaggcagatgatattgttggccccgtgacccatgaa atcttcgagaacaacgttgttcacttgatgtggcaggagcccaaggagcccaacggtctg attgtgctgtatgaagtgagttaccgacgatatggcgaggaggagctgcacctctgcgtc tcccgccggcattacgctctggagcgcggctgccggctgcgcgggctgctgcctgggaat tacagcgtgcgagttcgggccacctccctggcaggcaatgggtcttggacggaagccacc tatttctacgtgacagactatttagacgtgccatcaaatattgcaaaaatcatcatcggt cccctcatctttgtctttctcttcagtgttgtgattggaagcatttgtctattcctgaga aagaggcagccagatgggccactgggaccactgtatgcttcttcaaacccagagtacctc agtgccagcgatgtgttcccatgctctgtgtatgtgccggacgagtgggaggtgcctcga gagaagatcacactcctgcgagaattggggcaaggctccttcggcatggtgtacgagggc aacgccagggacattgtcaagggtgaggcggagacccgcgtggcagtgaagacggtcaac gagtcggccagcctgcgagagcggatcgagtttctcaacgaggcttcggtcatgaagggc ttcacctgccaccatgtggtccgcctcctgggagtggtgtccaaaggccagccaacactg gtggtgatggagttgatggctcacggagacctgaagagttacctccgttccctgcggcct gaggctgagaataaccccggccgccctccccctaccctgcaagaaatgattcagatggcg gcagagatcgccgatgggatggcatacctgaacgctaagaagttcgtgcaccgggatctt gcagcccggaactgcatggttgcccacgactttaccgtcaaaatcggagacttcggaatg acaagagacatctatgaaacggattactaccggaaagggggcaaaggtctgctccccgtg cggtggatggcacctgaatccctcaaggacggagtcttcaccacctcttcggacatgtgg tcttttggtgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggtctg tcaaatgagcaggtgctgaaatttgtcatggatggagggtacctggatcaacctgacaat tgtccagagagagttaccgacctgatgcggatgtgctggcagttcaaccccaagatgcgt ccaaccttcctggagatcgtggacctgctcaaggacgacctgcaccccagctttcccgaa gtgtccttcttccacagcgaggagaacaaggcgcccgagagcgaggagctggaaatggag tttgaggacatggagagcgtgccgctggaccggtcctcgcacgcgcagagagaggaggct gggggccgggacggagggtcggcgctggggctaaagcgaaactatgacgagcacatcccc tacacccacatgaacgggggcaagaaaaacggacggattctgactttgccccggtcaaat ccttcctaa

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