Otolemur garnettii (small-eared galago): 100940759
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Entry
100940759 CDS
T07855
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga04014
Ras signaling pathway
oga04137
Mitophagy - animal
oga04140
Autophagy - animal
oga04620
Toll-like receptor signaling pathway
oga04621
NOD-like receptor signaling pathway
oga04622
RIG-I-like receptor signaling pathway
oga04623
Cytosolic DNA-sensing pathway
oga04657
IL-17 signaling pathway
oga04936
Alcoholic liver disease
oga05014
Amyotrophic lateral sclerosis
oga05022
Pathways of neurodegeneration - multiple diseases
oga05135
Yersinia infection
oga05160
Hepatitis C
oga05161
Hepatitis B
oga05162
Measles
oga05163
Human cytomegalovirus infection
oga05164
Influenza A
oga05165
Human papillomavirus infection
oga05167
Kaposi sarcoma-associated herpesvirus infection
oga05168
Herpes simplex virus 1 infection
oga05169
Epstein-Barr virus infection
oga05170
Human immunodeficiency virus 1 infection
oga05171
Coronavirus disease - COVID-19
oga05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100940759 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100940759 (TBK1)
04137 Mitophagy - animal
100940759 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100940759 (TBK1)
04621 NOD-like receptor signaling pathway
100940759 (TBK1)
04622 RIG-I-like receptor signaling pathway
100940759 (TBK1)
04623 Cytosolic DNA-sensing pathway
100940759 (TBK1)
04657 IL-17 signaling pathway
100940759 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100940759 (TBK1)
05161 Hepatitis B
100940759 (TBK1)
05160 Hepatitis C
100940759 (TBK1)
05171 Coronavirus disease - COVID-19
100940759 (TBK1)
05164 Influenza A
100940759 (TBK1)
05162 Measles
100940759 (TBK1)
05168 Herpes simplex virus 1 infection
100940759 (TBK1)
05163 Human cytomegalovirus infection
100940759 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100940759 (TBK1)
05169 Epstein-Barr virus infection
100940759 (TBK1)
05165 Human papillomavirus infection
100940759 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100940759 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100940759 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
100940759 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100940759 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100940759 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oga01001
]
100940759 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oga04131
]
100940759 (TBK1)
Enzymes [BR:
oga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100940759 (TBK1)
Protein kinases [BR:
oga01001
]
Serine/threonine kinases: Other
IKK family [OT]
100940759 (TBK1)
Membrane trafficking [BR:
oga04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
100940759 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
ABC1
Kinase-like
DUF713
CEP63
SLATT_6
Motif
Other DBs
NCBI-GeneID:
100940759
NCBI-ProteinID:
XP_003798576
Ensembl:
ENSOGAG00000004958
UniProt:
H0WR08
LinkDB
All DBs
Position
Unknown
AA seq
729 aa
AA seq
DB search
MQSTPNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHGYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEDNPIFVVSREPLSTTGLIYEKISLPKVHPRYDLDGDASMAKAVTG
VVCYSCRTASTLLLYQELMRKGVRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQATIDSSLQDINTRLSPGGLLADTWAHQE
GTHPRDRSVEKLQVLLNSITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYQATKAMTL
FTDECIKKYEVFLDKSEDWMRKMLHLRKQLLSLTNQCFDVEEEVSKYQDYTSELQETLPQ
KMFAASSGLKHTMAPIYPSSNTLVEMTLGMKKLKEEMQGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcactcctaatcatctgtggcttctgtctgatattttaggccaaggagcaact
gcaaatgtctttcgtgggagacataagaaaaccggtgatttatttgctatcaaagtattt
aataatataagctttctccgtccagtggatgttcaaatgagagaatttgaagtattaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaagagacaacaacaaga
cataaagttcttattatggaattttgtccatgtgggagtttatacactgttttagaagag
ccatctaatgcctatggactaccagaatctgagtttttaattgttttgcgagatgtggtg
ggtggaatgaatcacctccgagagaacggcatagtgcaccgtgacatcaagccggggaac
atcatgcgtgttataggggaggacgggcagtctgtgtacaaactcacagacttcggtgca
gctagagaattggaagatgacgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctgagaaaagaccaccagaagaaatatggggcg
acagtggatctgtggagcattggggtgacgttctaccacgcggccactggctctctgccc
ttcagacccttcgaggggcctcgtaggaataaagaagtgatgtataaaataattacaggg
aagccttctggcgcgatatctggagtacagaaagcagaaaatgggccgattgactggagt
ggagacatgcctgtctcctgcagcctttctcggggtcttcaggtgctgcttacccctgtt
cttgcaaatatccttgaagcagatcaagaaaaatgttggggttttgaccagttttttgcc
gaaactagtgatatacttcaccgaatgataattcatgttttttcactgcaacaaatgaca
gctcataagatttacattcacggctataatactgctactgtatttcatgaactggtgtat
aaacaaaccaaaattatttcttcaaatcaagaacttatttatgaaggacgacgcttagtc
ctcgagcctggaagactggcccagcatttccctaaaactactgaggacaatcccatcttt
gtagtaagccgggaacccctgagtaccacagggttaatatatgaaaaaatttctcttcct
aaagtacatccacgttatgacttagacggggacgctagcatggccaaggcagttacaggg
gttgtgtgttactcctgccgaaccgccagcaccctgctgctttaccaggagttgatgcgg
aagggggtgcgatggttgattgaattagttaaagatgattacaacgaaactgttcacaaa
aagacagaagttgtgatcacgttagatttctgcatcagaaacattgaaaaaaccgtgaaa
gtatatgaaaagttgatgaagatcaacctggaagcagcagagttaggtgaaatttcagat
atacacaccaaattgttgaggctttccagttctcaggccacaatagactccagtctccag
gacatcaacaccaggttatccccaggtgggctgctggcggacacatgggcacaccaggaa
ggcactcaccccagagaccggagtgtagaaaaactacaagtcctgttaaattccatcaca
gagatttattatcagttcaaaaaggacaaagcagaacgaagactagcttataatgaagaa
caaatccacaaatttgataagcagaaactgtattaccaggccacaaaagctatgacactc
tttacagacgaatgtattaaaaagtacgaggtgtttctggacaagtcagaagactggatg
agaaagatgcttcatcttaggaagcagttattatctctgactaatcagtgttttgatgtt
gaagaagaagtgtcaaagtatcaagactacacaagcgagttacaagaaactttgcctcag
aagatgtttgcagcctccagtggactcaaacataccatggccccgatttacccgagttct
aacacattagtggagatgactctgggcatgaagaaattaaaggaggagatgcaaggggtg
gttaaagaacttgctgagaacaatcatattctagaaaggttcggctccctgaccatggac
ggcggccttcgcaatgttgactgtctttag
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