Otolemur garnettii (small-eared galago): 100953360
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Entry
100953360 CDS
T07855
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X2
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga00010
Glycolysis / Gluconeogenesis
oga00020
Citrate cycle (TCA cycle)
oga00620
Pyruvate metabolism
oga00785
Lipoic acid metabolism
oga01100
Metabolic pathways
oga01200
Carbon metabolism
oga01210
2-Oxocarboxylic acid metabolism
oga04066
HIF-1 signaling pathway
oga04922
Glucagon signaling pathway
oga05230
Central carbon metabolism in cancer
oga05415
Diabetic cardiomyopathy
Module
oga_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100953360 (PDHA1)
00020 Citrate cycle (TCA cycle)
100953360 (PDHA1)
00620 Pyruvate metabolism
100953360 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100953360 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100953360 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100953360 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100953360 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100953360 (PDHA1)
Enzymes [BR:
oga01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100953360 (PDHA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100953360
NCBI-ProteinID:
XP_003791981
Ensembl:
ENSOGAG00000002466
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSNPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgctgtctcccgcgtgttgtccggagctgcacagaagccagca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccggctggaagagggtcctcctgtcacaacagtgctcaccagagaggat
gggctcaaatactataggatgatgcagactgtgcgtcgaatggagttaaaagcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaggctggcataaatcccacagaccatctcatcacagcctatcgggct
catggctttaccttcactcggggcctttctgtccgagaaattcttgcagagctcacagga
cgaaaaggaggttgtgctaaagggaaaggaggatcgatgcatatgtatgccaagaacttc
tatggtggcaatggcatcgtcggagcccaggtgcccctgggagctgggattgccttggcc
tgtaagtataatggaaaagatgaggtctgtctgactttatatggtgatggtgctgctaac
cagggtcagatattcgaagcttacaacatggcagcattgtggaaattgccttgcattttc
atctgtgaaaataaccgctatgggatggggacgtctgttgagagagcagcggccagcact
gattactataagagaggcgatttcattcctgggctgagggtagatgggatggatatcctg
tgtgtcagggaggcaacaaggtttgcagctgcttattgtagatctgggaaggggcccatc
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgtgaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggataggatggtgaacaacaatcttgcaagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgccgctcagtttgctacagctgatcctgagccgcct
ttggaggaattaggctaccacatctacagcagcaacccaccttttgaagttcgtggtgcc
aatcagtggatcaagtttaagtcagtcagttaa
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integrated database retrieval system
