Otolemur garnettii (small-eared galago): 100962237 Help Entry 100962237         CDS       T07855                                  Symbol INSR Name (RefSeq) insulin receptor isoform X3   KO K04527   insulin receptor [EC:2.7.10.1] Organism oga  Otolemur garnettii (small-eared galago) Pathway oga04010   MAPK signaling pathway oga04014   Ras signaling pathway oga04015   Rap1 signaling pathway oga04022   cGMP-PKG signaling pathway oga04066   HIF-1 signaling pathway oga04068   FoxO signaling pathway oga04072   Phospholipase D signaling pathway oga04150   mTOR signaling pathway oga04151   PI3K-Akt signaling pathway oga04152   AMPK signaling pathway oga04211   Longevity regulating pathway oga04213   Longevity regulating pathway - multiple species oga04520   Adherens junction oga04910   Insulin signaling pathway oga04913   Ovarian steroidogenesis oga04923   Regulation of lipolysis in adipocytes oga04930   Type II diabetes mellitus oga04931   Insulin resistance oga04932   Non-alcoholic fatty liver disease oga04960   Aldosterone-regulated sodium reabsorption oga05010   Alzheimer disease oga05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:oga00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100962237 (INSR)    04014 Ras signaling pathway     100962237 (INSR)    04015 Rap1 signaling pathway     100962237 (INSR)    04066 HIF-1 signaling pathway     100962237 (INSR)    04068 FoxO signaling pathway     100962237 (INSR)    04072 Phospholipase D signaling pathway     100962237 (INSR)    04022 cGMP-PKG signaling pathway     100962237 (INSR)    04151 PI3K-Akt signaling pathway     100962237 (INSR)    04152 AMPK signaling pathway     100962237 (INSR)    04150 mTOR signaling pathway     100962237 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     100962237 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100962237 (INSR)    04923 Regulation of lipolysis in adipocytes     100962237 (INSR)    04913 Ovarian steroidogenesis     100962237 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100962237 (INSR)   09149 Aging    04211 Longevity regulating pathway     100962237 (INSR)    04213 Longevity regulating pathway - multiple species     100962237 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100962237 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100962237 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100962237 (INSR)    04932 Non-alcoholic fatty liver disease     100962237 (INSR)    04931 Insulin resistance     100962237 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oga01001]     100962237 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:oga04090]     100962237 (INSR) Enzymes [BR:oga01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      100962237 (INSR) Protein kinases [BR:oga01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    100962237 (INSR) CD molecules [BR:oga04090]  Proteins   100962237 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  100962237 NCBI-ProteinID:  XP_012669251 Ensembl:  ENSOGAG00000002968 LinkDB All DBs Position Unknown AA seq 1346 aa AA seqDB search MDIRNNLTRLRELENCSVIEGHLQILLMFKTSPEDFRDLSFPKLIMITDYLLLFRVYGLE SLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLAT IDWSRILDSVEDNYIVLNKDDNEECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQK VCPTVCKSHGCTAEGLCCHSECLGNCSEPDDPTKCMACRNFYLDGRCVEACPPPYYHFQD WRCVNFSFCYDLHNKCKNSRRPGCHQYVIHNRRCIPECPSGYTMNSSNLMCTPCLGPCPK VCHILESEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKI RRSYALVSLSFFRKLRLIRGETLEMGSYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHY NPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLKWE PYWPPDFRDLLGFMLFYKEAPYKNVTEFDGQDACGSNSWTVVDVDPPLRSNDPKSQNHPG WLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQ ILLKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKGLKLPSRTWSPPFESEDSQKH NQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRP SRKRRSLGEVGNVTMVAVPTVPGFPNISSTIMPTSPEEHRPFEKVVNKESLVISGLRHFT GYRIELQACNQDAPDERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKE PNGLIVLYEVSYRRYGDEELHLCVSRKHYALERGCRLRGLSPGNYSVRVRATSLAGNGSW TEATHFYMTDYLDVPSNIAKIIIGPLIFVFLFSIVIGSIYIFLRKRQPDGPLGPLYASSN PEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAV KTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLR SLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIG DFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQP YQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCFQFNPKMRPTFLEIVNLLKDDLHP SFPDVSFFHSEENKAPESEELEMEFEDMESVPLDRSSHCQREEAGGREGGSSLGLKRNYE EHIPYTHMNGGKRNGRILALPRSNPS NT seq 4041 nt NT seq  +upstreamnt  +downstreamnt atggatatccggaacaacctcaccaggctgcgggagctggagaactgctccgtcatcgaa ggccatttgcagatactcttgatgttcaaaacaagccctgaagacttccgagacctcagt ttccccaaactcataatgatcactgattacttgctgctcttccgggtctacgggttggag agcctgaaggacctgttccccaacctcactgttatccgaggctcacgcctcttcttcaac tatgccctagtcatctttgagatggttcacctgaaggagctcggtctctacaatctgatg aacataacccggggctccgtccgcatcgagaaaaacaatgagctctgctacttggccaca atcgactggtcccgcatcctggattctgtggaggacaattacattgtgttgaacaaggac gacaacgaggagtgtggggacgtctgtccagggactgccaagggcaagaccaactgccct gccaccgtcatcaacggccagtttgtggaacggtgctggactcacagtcattgccagaaa gtctgccccactgtctgcaagtcgcacggctgtactgccgaaggcctctgctgccatagc gagtgtctgggcaactgttctgagcctgatgaccccaccaagtgcatggcctgccgcaac ttctacctggacggcaggtgtgtggaggcctgcccacccccgtactaccacttccaggac tggcgctgcgtgaactttagcttctgctatgacctgcacaacaaatgcaagaactcacgg aggccgggctgccaccagtacgtcattcacaaccgcaggtgcattcctgaatgtccctct ggatacacaatgaactccagcaacctgatgtgcacaccgtgcctgggcccctgtcccaag gtctgccacatcctagaaagtgagaagaccatcgactcggtgacatctgcccaggagctc cgaggatgtactgttatcaacgggagtctgatcatcaacatccgagggggcaataacctg gcagcagagctagaagccaatcttggcctcattgaagaaatttcagggtatctgaaaatc cgtcgatcttacgctctggtgtcactttccttcttccggaagttacgtctgattcgagga gagaccttggaaatggggagctattctttctatgccttggacaaccagaacctaaggcag ctctgggactggagcaaacacaacctcaccatcactcaggggaaactcttcttccactac aatcccaaactctgcttgtcagaaatccacaagatggaagaagtttcaggaaccaagggc cgccaggagaggaacgacattgccctgaagaccaatggggaccaggcatcctgtgaaaat gaattacttaaattttcttacattcggacatcttttgacaagatcttgctgaaatgggag ccttactggccccccgacttccgagacctcttgggctttatgctgttctacaaagaggcc ccttataagaatgtgacagagttcgacgggcaggacgcttgtggttccaacagctggaca gtggtggacgtggacccccctttgaggtccaatgaccccaagtctcagaaccaccctggg tggctaatgcgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtc accttttcagatgaacgccggacctatggggccaagagtgacatcatttatgtccagaca gatgccaccaatccttccgtccccctggaccccatctcggtttctaattcctcatcccag attcttctgaagtggaagcccccctctgaccccaatggcaacatcactcactacctggtt ttctgggagaggcaggcggaagacagcgagctatatgagctggactattgcctcaaaggg ttgaagctgccctcccggacgtggtctccaccgtttgagtctgaggactctcagaagcac aaccagagtgagtacgaggactcggctggcgagtgctgctcctgccccaaaacagactct cagatcctgaaggagctggaggagtcctcgtttaggaagacgtttgaggactacctgcac aacgtggtcttcgtgcccagaaaaacctcttctggaactggtgctgaggatcctaggcca tctcggaagcgcaggtctctcggcgaagttggaaatgtgacgatggtggctgtgcccact gtcccaggtttccccaatatctcctcaaccatcatgcccacaagcccagaggagcacagg ccctttgagaaagtggtgaataaagagtcactggtcatctctggcctgcgacacttcacg ggctatcgcattgagctgcaagcttgcaaccaagatgccccggacgagcggtgcagtgtg gcggcctatgtcagtgccaggaccatgcctgaagccaaggctgatgacatcgtaggcccc gtgacccatgaaatcttcgagaacaacattgttcacttaatgtggcaggagccaaaggaa cccaatggtctgattgtgctgtatgaagtgagttatcggcgatatggtgatgaggagctg cacctctgcgtctcccgcaagcattatgctctggagcgaggctgcaggctgcgcgggctg tcgccagggaactacagcgtgcgagtcagggccacctccctggcgggcaatggttcctgg acagaagccacccatttctacatgacagactatctagatgtcccatcaaatattgcaaaa attatcattggcccccttatctttgtctttctcttcagtattgtgattggaagtatttat atattcctgagaaaaaggcagccagatgggccactgggaccactgtacgcatcctcaaac ccagagtacctcagtgccagtgatgtgtttccttgttctgtgtatgtgccggacgagtgg gaggtgcctcgagagaagatcaccctccttcgagagctgggacagggttcctttggcatg gtgtacgagggcaatgccagggacatcgtcaagggtgaggcggagacccgagtggcagtg aagactgtcaatgagtcggccagtctccgggagcggatcgagttcctcaatgaggcttca gttatgaagggtttcacctgtcatcatgtggtccgcctcctgggggtggtgtctaagggg cagccaacgttggtggtgatggagttgatggctcacggagacctgaagagctacctccgt tctctgcggcccgaggctgagaataacccaggtcgccctcccccaaccttgcaagagatg attcagatggcagcggagattgccgatgggatggcatacctgaatgccaagaagtttgtg caccgggacctcgctgctagaaactgcatggttgctcacgatttcactgtcaaaattgga gactttggaatgaccagagacatctacgagaccgattactacaggaaagggggcaagggc ctgttgcccgtgcggtggatggcaccagagtctctgaaggatggggtctttaccacttct tctgacatgtggtccttcggcgtggtcctttgggaaatcaccagcttggcagagcagcct taccaaggcctatctaatgaacaggtgttaaaatttgtcatggatgggggctacctggat caacctgacaactgtccagagagagtcacggacctgatgcgcatgtgcttccagttcaac cccaagatgcggccaacctttctggagatcgtcaacctgctcaaggacgacctgcaccct agcttcccagacgtttccttcttccacagcgaggagaacaaggctcctgagagtgaggag ctggagatggagtttgaggacatggagagcgtccccctggaccggtcctcacactgccag agggaggaggctgggggccgagaaggagggtcctcgctgggcctcaagcggaactatgag gagcacatcccctacacccacatgaacgggggcaagagaaacgggcggattctggccttg cctcgctccaacccctcctaa

DBGET integrated database retrieval system