KEGG   Otolemur garnettii (small-eared galago): 100962457
Entry
100962457         CDS       T07855                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga04010  MAPK signaling pathway
oga04015  Rap1 signaling pathway
oga04218  Cellular senescence
oga04380  Osteoclast differentiation
oga04620  Toll-like receptor signaling pathway
oga04664  Fc epsilon RI signaling pathway
oga04668  TNF signaling pathway
oga04750  Inflammatory mediator regulation of TRP channels
oga04912  GnRH signaling pathway
oga04935  Growth hormone synthesis, secretion and action
oga04936  Alcoholic liver disease
oga05014  Amyotrophic lateral sclerosis
oga05022  Pathways of neurodegeneration - multiple diseases
oga05132  Salmonella infection
oga05135  Yersinia infection
oga05145  Toxoplasmosis
oga05161  Hepatitis B
oga05163  Human cytomegalovirus infection
oga05167  Kaposi sarcoma-associated herpesvirus infection
oga05169  Epstein-Barr virus infection
oga05170  Human immunodeficiency virus 1 infection
oga05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oga05417  Lipid and atherosclerosis
oga05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oga00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100962457 (MAP2K6)
   04015 Rap1 signaling pathway
    100962457 (MAP2K6)
   04668 TNF signaling pathway
    100962457 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100962457 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100962457 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    100962457 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100962457 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    100962457 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100962457 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100962457 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100962457 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100962457 (MAP2K6)
   05161 Hepatitis B
    100962457 (MAP2K6)
   05163 Human cytomegalovirus infection
    100962457 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100962457 (MAP2K6)
   05169 Epstein-Barr virus infection
    100962457 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100962457 (MAP2K6)
   05135 Yersinia infection
    100962457 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100962457 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100962457 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    100962457 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100962457 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    100962457 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100962457 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oga01001]
    100962457 (MAP2K6)
Enzymes [BR:oga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100962457 (MAP2K6)
Protein kinases [BR:oga01001]
 Serine/threonine kinases: STE group
  STE7 family
   100962457 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal APH
Other DBs
NCBI-GeneID: 100962457
NCBI-ProteinID: XP_023366977
Ensembl: ENSOGAG00000010406
LinkDB
Position
Unknown
AA seq 364 aa
KPHQSLLCWSLAVLGCQRWASKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQN
FEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMR
TVDCPFTVTFYGALFREVGGRSIQSLRTIDSADSNENASPCDLRLRIIKLGILNIQFLSS
HVVNKSLFLLQIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAK
TIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQV
VEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKATDVASFVKL
ILGD
NT seq 1095 nt   +upstreamnt  +downstreamnt
aaacctcatcagagtctcctctgctggtctctcgctgtgctgggctgtcagagatgggca
agcaagaagcgaaaccctggccttaaaatccccaaagaagcgtttgaacaacctcagacc
agttccacgccacctcgagacttagactccaaggcttgcatttctattgggaatcagaac
tttgaggtgaaggcagatgacctggagcctatagtggagctggggcgaggtgcgtatggg
gtggtagagaagatgaggcacgtccccagcgggcagatcatggcggtgaagaggatccgg
gccacagtaaatagccaagagcagaaacggctactgatggatttggacatttccatgagg
acagtggactgtccgttcaccgtcaccttttatggcgcgctcttccgggaggtaggtggt
agatcaattcaaagtttaagaactatagattcagccgactccaatgaaaatgcctcacct
tgcgatctcaggctaaggataataaaactgggcatacttaacattcaatttctttctagc
catgtggtaaataaatctttgtttctcttgcagatcgtaaaagcattagagcatttacac
agtaagctctccgtcattcatcgagatgtcaagccttctaatgtgctcattaatgctctg
ggccaagtgaagatgtgcgactttggaatcagtggctacctggtggactctgtcgctaaa
acaattgacgcaggttgcaaaccgtacatggcccctgaaagaataaacccagagctcaat
cagaagggatacagtgtgaagtcggacatttggagtctgggcatcacaatgattgagctg
gccatcctccggtttccctatgattcgtggggaactccttttcagcagctcaaacaggtg
gtggaggagccatcgccgcaactcccggcagacaagttttctgcagagtttgttgacttt
acctcacagtgcttgaagaagaattccaaagaacggcctacatacccagaactcatgcaa
catccatttttcaccctacatgaatccaaagcaacagatgtggcatcttttgtaaaactg
attcttggagactaa

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