KEGG   Otolemur garnettii (small-eared galago): 100967053
Entry
100967053         CDS       T07855                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga01522  Endocrine resistance
oga04010  MAPK signaling pathway
oga04012  ErbB signaling pathway
oga04014  Ras signaling pathway
oga04024  cAMP signaling pathway
oga04068  FoxO signaling pathway
oga04071  Sphingolipid signaling pathway
oga04137  Mitophagy - animal
oga04140  Autophagy - animal
oga04141  Protein processing in endoplasmic reticulum
oga04210  Apoptosis
oga04215  Apoptosis - multiple species
oga04217  Necroptosis
oga04310  Wnt signaling pathway
oga04380  Osteoclast differentiation
oga04510  Focal adhesion
oga04530  Tight junction
oga04620  Toll-like receptor signaling pathway
oga04621  NOD-like receptor signaling pathway
oga04622  RIG-I-like receptor signaling pathway
oga04625  C-type lectin receptor signaling pathway
oga04657  IL-17 signaling pathway
oga04658  Th1 and Th2 cell differentiation
oga04659  Th17 cell differentiation
oga04660  T cell receptor signaling pathway
oga04664  Fc epsilon RI signaling pathway
oga04668  TNF signaling pathway
oga04722  Neurotrophin signaling pathway
oga04723  Retrograde endocannabinoid signaling
oga04728  Dopaminergic synapse
oga04750  Inflammatory mediator regulation of TRP channels
oga04910  Insulin signaling pathway
oga04912  GnRH signaling pathway
oga04914  Progesterone-mediated oocyte maturation
oga04917  Prolactin signaling pathway
oga04920  Adipocytokine signaling pathway
oga04926  Relaxin signaling pathway
oga04930  Type II diabetes mellitus
oga04931  Insulin resistance
oga04932  Non-alcoholic fatty liver disease
oga04933  AGE-RAGE signaling pathway in diabetic complications
oga04935  Growth hormone synthesis, secretion and action
oga04936  Alcoholic liver disease
oga05010  Alzheimer disease
oga05012  Parkinson disease
oga05016  Huntington disease
oga05017  Spinocerebellar ataxia
oga05020  Prion disease
oga05022  Pathways of neurodegeneration - multiple diseases
oga05132  Salmonella infection
oga05133  Pertussis
oga05135  Yersinia infection
oga05142  Chagas disease
oga05145  Toxoplasmosis
oga05152  Tuberculosis
oga05161  Hepatitis B
oga05162  Measles
oga05166  Human T-cell leukemia virus 1 infection
oga05167  Kaposi sarcoma-associated herpesvirus infection
oga05169  Epstein-Barr virus infection
oga05170  Human immunodeficiency virus 1 infection
oga05171  Coronavirus disease - COVID-19
oga05200  Pathways in cancer
oga05208  Chemical carcinogenesis - reactive oxygen species
oga05210  Colorectal cancer
oga05212  Pancreatic cancer
oga05231  Choline metabolism in cancer
oga05415  Diabetic cardiomyopathy
oga05417  Lipid and atherosclerosis
oga05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oga00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100967053 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100967053 (MAPK8)
   04012 ErbB signaling pathway
    100967053 (MAPK8)
   04014 Ras signaling pathway
    100967053 (MAPK8)
   04310 Wnt signaling pathway
    100967053 (MAPK8)
   04668 TNF signaling pathway
    100967053 (MAPK8)
   04068 FoxO signaling pathway
    100967053 (MAPK8)
   04071 Sphingolipid signaling pathway
    100967053 (MAPK8)
   04024 cAMP signaling pathway
    100967053 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100967053 (MAPK8)
   04137 Mitophagy - animal
    100967053 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    100967053 (MAPK8)
   04215 Apoptosis - multiple species
    100967053 (MAPK8)
   04217 Necroptosis
    100967053 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100967053 (MAPK8)
   04530 Tight junction
    100967053 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100967053 (MAPK8)
   04621 NOD-like receptor signaling pathway
    100967053 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    100967053 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    100967053 (MAPK8)
   04660 T cell receptor signaling pathway
    100967053 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    100967053 (MAPK8)
   04659 Th17 cell differentiation
    100967053 (MAPK8)
   04657 IL-17 signaling pathway
    100967053 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    100967053 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100967053 (MAPK8)
   04920 Adipocytokine signaling pathway
    100967053 (MAPK8)
   04912 GnRH signaling pathway
    100967053 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    100967053 (MAPK8)
   04917 Prolactin signaling pathway
    100967053 (MAPK8)
   04926 Relaxin signaling pathway
    100967053 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    100967053 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    100967053 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    100967053 (MAPK8)
   04722 Neurotrophin signaling pathway
    100967053 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100967053 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100967053 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967053 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    100967053 (MAPK8)
   05231 Choline metabolism in cancer
    100967053 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100967053 (MAPK8)
   05212 Pancreatic cancer
    100967053 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100967053 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    100967053 (MAPK8)
   05161 Hepatitis B
    100967053 (MAPK8)
   05171 Coronavirus disease - COVID-19
    100967053 (MAPK8)
   05162 Measles
    100967053 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100967053 (MAPK8)
   05169 Epstein-Barr virus infection
    100967053 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100967053 (MAPK8)
   05135 Yersinia infection
    100967053 (MAPK8)
   05133 Pertussis
    100967053 (MAPK8)
   05152 Tuberculosis
    100967053 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100967053 (MAPK8)
   05142 Chagas disease
    100967053 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100967053 (MAPK8)
   05012 Parkinson disease
    100967053 (MAPK8)
   05016 Huntington disease
    100967053 (MAPK8)
   05017 Spinocerebellar ataxia
    100967053 (MAPK8)
   05020 Prion disease
    100967053 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    100967053 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100967053 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    100967053 (MAPK8)
   05415 Diabetic cardiomyopathy
    100967053 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100967053 (MAPK8)
   04936 Alcoholic liver disease
    100967053 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    100967053 (MAPK8)
   04931 Insulin resistance
    100967053 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100967053 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100967053 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oga01001]
    100967053 (MAPK8)
Enzymes [BR:oga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100967053 (MAPK8)
Protein kinases [BR:oga01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100967053 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 100967053
NCBI-ProteinID: XP_003801693
Ensembl: ENSOGAG00000008164
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacgttc
acagtcctgaaacgataccagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgctgcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcaaaatcaaacccatgctaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatctctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagctagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattatccatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggtttggcccggactgcaggaacaagtttt
atgatgacgccttatgtagtgactcgctactatagagcacctgaggtcatcctaggcatg
ggctacaaggaaaatgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
ctcggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcagaacacaacaaacttaaagccagccaggcaagggatttgttatctaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccagcacccatat
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgataaa
caattagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcgatgtcaacagatccgactttggcctcggatacagacagcagtttagaagcatcagct
gggcctctgggctgctgtagatga

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