Otolemur garnettii (small-eared galago): 100967053
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Entry
100967053 CDS
T07855
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga01522
Endocrine resistance
oga04010
MAPK signaling pathway
oga04012
ErbB signaling pathway
oga04014
Ras signaling pathway
oga04024
cAMP signaling pathway
oga04068
FoxO signaling pathway
oga04071
Sphingolipid signaling pathway
oga04137
Mitophagy - animal
oga04140
Autophagy - animal
oga04141
Protein processing in endoplasmic reticulum
oga04210
Apoptosis
oga04215
Apoptosis - multiple species
oga04217
Necroptosis
oga04310
Wnt signaling pathway
oga04380
Osteoclast differentiation
oga04510
Focal adhesion
oga04530
Tight junction
oga04620
Toll-like receptor signaling pathway
oga04621
NOD-like receptor signaling pathway
oga04622
RIG-I-like receptor signaling pathway
oga04625
C-type lectin receptor signaling pathway
oga04657
IL-17 signaling pathway
oga04658
Th1 and Th2 cell differentiation
oga04659
Th17 cell differentiation
oga04660
T cell receptor signaling pathway
oga04664
Fc epsilon RI signaling pathway
oga04668
TNF signaling pathway
oga04722
Neurotrophin signaling pathway
oga04723
Retrograde endocannabinoid signaling
oga04728
Dopaminergic synapse
oga04750
Inflammatory mediator regulation of TRP channels
oga04910
Insulin signaling pathway
oga04912
GnRH signaling pathway
oga04914
Progesterone-mediated oocyte maturation
oga04917
Prolactin signaling pathway
oga04920
Adipocytokine signaling pathway
oga04926
Relaxin signaling pathway
oga04930
Type II diabetes mellitus
oga04931
Insulin resistance
oga04932
Non-alcoholic fatty liver disease
oga04933
AGE-RAGE signaling pathway in diabetic complications
oga04935
Growth hormone synthesis, secretion and action
oga04936
Alcoholic liver disease
oga05010
Alzheimer disease
oga05012
Parkinson disease
oga05016
Huntington disease
oga05017
Spinocerebellar ataxia
oga05020
Prion disease
oga05022
Pathways of neurodegeneration - multiple diseases
oga05132
Salmonella infection
oga05133
Pertussis
oga05135
Yersinia infection
oga05142
Chagas disease
oga05145
Toxoplasmosis
oga05152
Tuberculosis
oga05161
Hepatitis B
oga05162
Measles
oga05166
Human T-cell leukemia virus 1 infection
oga05167
Kaposi sarcoma-associated herpesvirus infection
oga05169
Epstein-Barr virus infection
oga05170
Human immunodeficiency virus 1 infection
oga05171
Coronavirus disease - COVID-19
oga05200
Pathways in cancer
oga05208
Chemical carcinogenesis - reactive oxygen species
oga05210
Colorectal cancer
oga05212
Pancreatic cancer
oga05231
Choline metabolism in cancer
oga05415
Diabetic cardiomyopathy
oga05417
Lipid and atherosclerosis
oga05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100967053 (MAPK8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100967053 (MAPK8)
04012 ErbB signaling pathway
100967053 (MAPK8)
04014 Ras signaling pathway
100967053 (MAPK8)
04310 Wnt signaling pathway
100967053 (MAPK8)
04668 TNF signaling pathway
100967053 (MAPK8)
04068 FoxO signaling pathway
100967053 (MAPK8)
04071 Sphingolipid signaling pathway
100967053 (MAPK8)
04024 cAMP signaling pathway
100967053 (MAPK8)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100967053 (MAPK8)
04137 Mitophagy - animal
100967053 (MAPK8)
09143 Cell growth and death
04210 Apoptosis
100967053 (MAPK8)
04215 Apoptosis - multiple species
100967053 (MAPK8)
04217 Necroptosis
100967053 (MAPK8)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100967053 (MAPK8)
04530 Tight junction
100967053 (MAPK8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100967053 (MAPK8)
04621 NOD-like receptor signaling pathway
100967053 (MAPK8)
04622 RIG-I-like receptor signaling pathway
100967053 (MAPK8)
04625 C-type lectin receptor signaling pathway
100967053 (MAPK8)
04660 T cell receptor signaling pathway
100967053 (MAPK8)
04658 Th1 and Th2 cell differentiation
100967053 (MAPK8)
04659 Th17 cell differentiation
100967053 (MAPK8)
04657 IL-17 signaling pathway
100967053 (MAPK8)
04664 Fc epsilon RI signaling pathway
100967053 (MAPK8)
09152 Endocrine system
04910 Insulin signaling pathway
100967053 (MAPK8)
04920 Adipocytokine signaling pathway
100967053 (MAPK8)
04912 GnRH signaling pathway
100967053 (MAPK8)
04914 Progesterone-mediated oocyte maturation
100967053 (MAPK8)
04917 Prolactin signaling pathway
100967053 (MAPK8)
04926 Relaxin signaling pathway
100967053 (MAPK8)
04935 Growth hormone synthesis, secretion and action
100967053 (MAPK8)
09156 Nervous system
04728 Dopaminergic synapse
100967053 (MAPK8)
04723 Retrograde endocannabinoid signaling
100967053 (MAPK8)
04722 Neurotrophin signaling pathway
100967053 (MAPK8)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100967053 (MAPK8)
09158 Development and regeneration
04380 Osteoclast differentiation
100967053 (MAPK8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100967053 (MAPK8)
05208 Chemical carcinogenesis - reactive oxygen species
100967053 (MAPK8)
05231 Choline metabolism in cancer
100967053 (MAPK8)
09162 Cancer: specific types
05210 Colorectal cancer
100967053 (MAPK8)
05212 Pancreatic cancer
100967053 (MAPK8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100967053 (MAPK8)
05170 Human immunodeficiency virus 1 infection
100967053 (MAPK8)
05161 Hepatitis B
100967053 (MAPK8)
05171 Coronavirus disease - COVID-19
100967053 (MAPK8)
05162 Measles
100967053 (MAPK8)
05167 Kaposi sarcoma-associated herpesvirus infection
100967053 (MAPK8)
05169 Epstein-Barr virus infection
100967053 (MAPK8)
09171 Infectious disease: bacterial
05132 Salmonella infection
100967053 (MAPK8)
05135 Yersinia infection
100967053 (MAPK8)
05133 Pertussis
100967053 (MAPK8)
05152 Tuberculosis
100967053 (MAPK8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100967053 (MAPK8)
05142 Chagas disease
100967053 (MAPK8)
09164 Neurodegenerative disease
05010 Alzheimer disease
100967053 (MAPK8)
05012 Parkinson disease
100967053 (MAPK8)
05016 Huntington disease
100967053 (MAPK8)
05017 Spinocerebellar ataxia
100967053 (MAPK8)
05020 Prion disease
100967053 (MAPK8)
05022 Pathways of neurodegeneration - multiple diseases
100967053 (MAPK8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100967053 (MAPK8)
05418 Fluid shear stress and atherosclerosis
100967053 (MAPK8)
05415 Diabetic cardiomyopathy
100967053 (MAPK8)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100967053 (MAPK8)
04936 Alcoholic liver disease
100967053 (MAPK8)
04932 Non-alcoholic fatty liver disease
100967053 (MAPK8)
04931 Insulin resistance
100967053 (MAPK8)
04933 AGE-RAGE signaling pathway in diabetic complications
100967053 (MAPK8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100967053 (MAPK8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oga01001
]
100967053 (MAPK8)
Enzymes [BR:
oga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
100967053 (MAPK8)
Protein kinases [BR:
oga01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
100967053 (MAPK8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
FTA2
APH
DUF530
Motif
Other DBs
NCBI-GeneID:
100967053
NCBI-ProteinID:
XP_003801693
Ensembl:
ENSOGAG00000008164
LinkDB
All DBs
Position
Unknown
AA seq
427 aa
AA seq
DB search
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacgttc
acagtcctgaaacgataccagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgctgcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcaaaatcaaacccatgctaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatctctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagctagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattatccatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggtttggcccggactgcaggaacaagtttt
atgatgacgccttatgtagtgactcgctactatagagcacctgaggtcatcctaggcatg
ggctacaaggaaaatgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
ctcggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcagaacacaacaaacttaaagccagccaggcaagggatttgttatctaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccagcacccatat
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgataaa
caattagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcgatgtcaacagatccgactttggcctcggatacagacagcagtttagaagcatcagct
gggcctctgggctgctgtagatga
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