Orcinus orca (killer whale): 101272028
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Entry
101272028 CDS
T05247
Symbol
GLS
Name
(RefSeq) glutaminase kidney isoform, mitochondrial isoform X2
KO
K01425
glutaminase [EC:
3.5.1.2
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00220
Arginine biosynthesis
oor00250
Alanine, aspartate and glutamate metabolism
oor00470
D-Amino acid metabolism
oor01100
Metabolic pathways
oor04724
Glutamatergic synapse
oor04727
GABAergic synapse
oor04964
Proximal tubule bicarbonate reclamation
oor05206
MicroRNAs in cancer
oor05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
101272028 (GLS)
00220 Arginine biosynthesis
101272028 (GLS)
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
101272028 (GLS)
09150 Organismal Systems
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
101272028 (GLS)
09156 Nervous system
04724 Glutamatergic synapse
101272028 (GLS)
04727 GABAergic synapse
101272028 (GLS)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101272028 (GLS)
05230 Central carbon metabolism in cancer
101272028 (GLS)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.2 glutaminase
101272028 (GLS)
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GFIT
Motif
Pfam:
Glutaminase
EF-hand_14
Motif
Other DBs
NCBI-GeneID:
101272028
NCBI-ProteinID:
XP_004276990
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Position
7:77267128..77350089
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AA seq
612 aa
AA seq
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MMRLRGSAMLRDLLLRPPADACAVLRRAQPLATLCRRPRGGGRAGQAAAARLYPWWGGGG
RPAGPLVRGLSSSPSEILQELGKGGTPPQQQQPQQQPPPPPQQPQPGASPPAAPPASGPK
DGSGETDGIGNSEGKELVVSGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKST
GLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMS
FTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQS
CVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIK
QGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTD
MVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMY
DFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCN
FHNYDNLRHFAKKLDPRREGGDQRHSFGPLDYESLQQELALKETVWKKVSPESNEDISTT
VVYRMESLGEKS
NT seq
1839 nt
NT seq
+upstream
nt +downstream
nt
atgatgcggctgcgaggctcggcgatgctgcgggacctgctccttcgcccgcccgccgac
gcctgcgcggttctgaggcgggcgcagcccctcgccaccctgtgccggcgcccccggggc
gggggacgagctggccaggcggccgccgcgcggctctacccgtggtggggcgggggcggc
cggccggcgggacccctcgtgaggggcctgtccagctccccctcagagatcctgcaggag
ctgggcaaggggggcacgccgccgcagcagcagcagccgcagcagcagccgccgccgcct
ccgcagcagccgcagcccggggcgtcgccgcccgcggccccgccggcgtccggccccaag
gacggctcgggggagacagacgggatcggcaacagcgagggcaaggagctggtggtttca
ggcgaaaataaaataaagcagggtctgttacctagcttggaagatttgctattctataca
atcgcagaaggacaagagaaaatacctgttcataaatttattacagcactcaaatctaca
ggattgcgaacgtctgatcccaggttgaaagagtgtatggatatgttaagattaactctt
caaacaacatcagatggtgtcatgctagacaaagatctttttaaaaaatgtgttcaaagc
aacattgttttgttgacacaagcctttagaagaaagtttgtcattcctgactttatgtct
tttacttcacacattgatgagttatatgagagtgctaaaaagcagtctggaggaaaggtt
gcagattatattcctcagttagccaagttcagtcctgatttgtggggtgtgtccgtttgt
acagtagatggacagaggcattctattggggataccaaagttccattttgccttcaatcc
tgtgtaaaacctttgaaatatgccattgctgttaatgatcttggaacagaatatgtgcat
cgatatgttgggaaagagccaagtggattaaggttcaacaaactgttcttaaatgaagat
gataaaccacacaatcctatggtaaatgctggagcaattgttgtgacttcattaataaag
caaggagtgaataatgctgaaaaatttgactatgtaatgcaatttttgaataagatggct
ggtaatgagtatgttggattcagtaatgcaacgtttcagtctgaaagagaaagtggagat
cgaaattttgcaataggatattacttaaaagaaaaaaagtgttttccagaaggtacagac
atggttggtatattagacttctatttccagctatgctccattgaagtaacatgtgaatca
gctagtgtgatggcggcaacactggctaatggtggcttctgcccaattactggggaaaga
gtactgagtcctgaagcagttcgaaatacactcagtttgatgcattcctgtggcatgtat
gatttctcggggcagtttgctttccatgttggtcttcctgcaaaatctggagttgctggg
ggcattcttttagttgtccccaatgtcatgggcatgatgtgctggtctcctcccctggac
aagatgggcaacagtgttaagggaattcacttctgtcacgatcttgtttctctgtgtaat
ttccataactatgataatttgagacactttgcaaaaaaacttgatcctcgaagagaaggt
ggtgatcaaaggcattcctttggaccattggactatgaaagtctccaacaagaacttgct
ttaaaagagacagtatggaaaaaagtgtcacctgagtcaaatgaggacatctctacaact
gtagtatatagaatggaaagtctgggagagaaaagctaa
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