Orcinus orca (killer whale): 101288086
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Entry
101288086 CDS
T05247
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1 isoform X2
KO
K04409
p21-activated kinase 1 [EC:
2.7.11.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04010
MAPK signaling pathway
oor04012
ErbB signaling pathway
oor04014
Ras signaling pathway
oor04024
cAMP signaling pathway
oor04062
Chemokine signaling pathway
oor04360
Axon guidance
oor04392
Hippo signaling pathway - multiple species
oor04510
Focal adhesion
oor04625
C-type lectin receptor signaling pathway
oor04650
Natural killer cell mediated cytotoxicity
oor04660
T cell receptor signaling pathway
oor04666
Fc gamma R-mediated phagocytosis
oor04810
Regulation of actin cytoskeleton
oor05132
Salmonella infection
oor05170
Human immunodeficiency virus 1 infection
oor05205
Proteoglycans in cancer
oor05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101288086 (PAK1)
04012 ErbB signaling pathway
101288086 (PAK1)
04014 Ras signaling pathway
101288086 (PAK1)
04392 Hippo signaling pathway - multiple species
101288086 (PAK1)
04024 cAMP signaling pathway
101288086 (PAK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101288086 (PAK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101288086 (PAK1)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
101288086 (PAK1)
04650 Natural killer cell mediated cytotoxicity
101288086 (PAK1)
04660 T cell receptor signaling pathway
101288086 (PAK1)
04666 Fc gamma R-mediated phagocytosis
101288086 (PAK1)
04062 Chemokine signaling pathway
101288086 (PAK1)
09158 Development and regeneration
04360 Axon guidance
101288086 (PAK1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101288086 (PAK1)
09162 Cancer: specific types
05211 Renal cell carcinoma
101288086 (PAK1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101288086 (PAK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
101288086 (PAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101288086 (PAK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oor04131
]
101288086 (PAK1)
03036 Chromosome and associated proteins [BR:
oor03036
]
101288086 (PAK1)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101288086 (PAK1)
Protein kinases [BR:
oor01001
]
Serine/threonine kinases: STE group
STE20 family
101288086 (PAK1)
Membrane trafficking [BR:
oor04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
101288086 (PAK1)
Endocytosis
Macropinocytosis
Kinases
101288086 (PAK1)
Chromosome and associated proteins [BR:
oor03036
]
Eukaryotic type
Sister chromatid separation proteins
Aurora kinases
Regulators of Aurora kinases
101288086 (PAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
ABC1
Kinase-like
Pkinase_fungal
APH
DSHCT
Kdo
Motif
Other DBs
NCBI-GeneID:
101288086
NCBI-ProteinID:
XP_004279876
LinkDB
All DBs
Position
8:complement(54585343..54782799)
Genome browser
AA seq
544 aa
AA seq
DB search
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRAILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVLPVSEDEDDD
DDATPPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSSQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq
1635 nt
NT seq
+upstream
nt +downstream
nt
atgtcgaataacggcctagatattcaagacaaacccccagcccctccgatgagaaatacc
agcactatgattggagctggcagcaaagatgctggaaccctaaaccacggttccaaacct
ctgcctccaaacccagaggagaagaaaaagaaggaccgattttaccgagccatcttacct
ggtgataaaacaaataaaaagaaggagaaggaacggccagagatttctcttccttcagat
tttgagcacacgattcacgttggttttgatgctgtcacaggcgagtttacagggatgcca
gagcagtgggcccgcttgcttcagacatcaaatatcaccaagtcggagcagaagaaaaac
ccgcaggctgtcctggatgtattagaattttataactcgaagaagacctccaacagccag
aagtacatgagctttacagataaatcagctgaggattataattcttctaacactttgaac
gtgaagacggtgtctgagacccctgcagtgctaccagtttcagaagatgaagatgatgat
gatgatgctaccccacctccagtgattgctccacgcccagagcacacaaaatcggtatac
acacggtccgtgattgaaccacttcctattactccaactcgggatgtggctacgtctccc
atttcacctactgagaataataccactccgccagatgctctgacccggaatactgagaag
cagaagaagaagcctaaaatgtctgatgaggagatcttggagaaattacggagcatagtg
agtgtgggtgatcctaagaagaaatacacacggtttgagaagattggacaaggtgcttca
ggcactgtgtacactgcaatggatgtggccacaggacaggaggtggccattaagcagatg
aaccttcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagttacctcgtgggagatgagctatgg
gttgtcatggaatatttggctggaggttctttgacagacgtggtaacagaaacctgcatg
gatgaaggccagattgcagctgtgtgccgtgagtgcctgcaggctttggagtttctgcat
tcgagccaagttattcatagagacatcaagagtgacaacatcctgttgggaatggatggc
tccgtcaagctaactgactttggattctgtgcccagatcaccccagagcagagcaaacgg
agcaccatggtgggaacaccgtactggatggcaccagaggttgtgacacggaaggcctat
gggcctaaggttgacatttggtccctgggcatcatggccatcgaaatgattgaaggggag
cccccataccttaatgaaaatcctctgagagccttgtacctcatcgccaccaatgggacc
ccggagcttcagaacccagagaagctgtcagctatcttccgagactttctgaaccgctgt
cttgaaatggatgtggagaagagaggttcagctaaagagctgttgcagcatcagttcctg
aagattgccaagcccctctccagcctcactccactgattgctgccgcaaaggaggcaacc
aagaacaatcactaa
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