Ochotona princeps (American pika): 101518566
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Entry
101518566 CDS
T07609
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi04064
NF-kappa B signaling pathway
opi04380
Osteoclast differentiation
opi04650
Natural killer cell mediated cytotoxicity
opi04658
Th1 and Th2 cell differentiation
opi04659
Th17 cell differentiation
opi04660
T cell receptor signaling pathway
opi05135
Yersinia infection
opi05166
Human T-cell leukemia virus 1 infection
opi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
opi05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
101518566 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101518566 (LCK)
04660 T cell receptor signaling pathway
101518566 (LCK)
04658 Th1 and Th2 cell differentiation
101518566 (LCK)
04659 Th17 cell differentiation
101518566 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
101518566 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101518566 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101518566 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
101518566 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
101518566 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101518566 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
opi03036
]
101518566 (LCK)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101518566 (LCK)
Protein kinases [BR:
opi01001
]
Non-receptor tyrosine kinases
SRC family
101518566 (LCK)
Chromosome and associated proteins [BR:
opi03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
101518566 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH3_16
SH3_3
Kdo
Motif
Other DBs
NCBI-GeneID:
101518566
NCBI-ProteinID:
XP_004591680
LinkDB
All DBs
Position
13:22722337..22746643
Genome browser
AA seq
509 aa
AA seq
DB search
MGCSCSSNPEDDWMENIDVCENCHYPIVPLEGKSMLLMRNGSEVRDPLVTYEGSIPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRVLEQNGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVRHYTNTPDGLCTRLSRPCQTSKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMKLCWKER
PEERPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtagctgcagttcaaaccctgaagatgactggatggaaaacattgacgtgtgt
gagaactgccactatcccattgtccccttggaaggcaagtccatgctgctcatgcggaat
ggctctgaggttcgggacccgctagtcacctatgaaggctccattcctccagcgtcccca
ctgcaagacaacctggttatcgccctgcacagctatgagccctctcatgacggagacctg
ggcttcgaaaagggcgaacagctccgtgtcctggagcagaacggcgagtggtggaaggcg
cagtccctgaccactggccaggaaggcttcatccccttcaacttcgtggccaaagccaac
agcctggagcctgagccctggttcttcaagaacctgagccgcaaggacgccgagcggcag
ctcttggcgccagggaacacgcacggctccttcctgatccgggagagcgagagcaccgcg
ggttcattttcactatcggtccgggattttgaccaaaaccagggagaggtggtgaaacat
tataagatccgtaacctggacaacggcggcttctacatctcccctcgcatcacttttccc
ggcctgcacgagctggtccgccattacaccaatactccggatgggctgtgcacccggttg
agccgcccctgtcagacctcgaagcctcagaagccgtggtgggaggacgagtgggaggtg
cccagggagacgctgaagctggtggagcgactgggggccggccagtttggggaggtgtgg
atggggtactacaacgggcacacaaaggtggccgtgaagagcctgaagcagggcagcatg
tctccagacgccttcctggcggaagccaacctcatgaagcagctgcagcaccaacggctg
gtccggttgtacgcggtggtcacccaggagcccatctatatcatcacagaatacatggag
aacggcagcttagtggattttctcaagaccccttcgggtatcaagctgaccatcaacaaa
ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcggaattat
attcaccgcgacctgcgggccgccaacatcctggtgtctgacaccctcagctgtaagatt
gccgactttggcctcgcacgtctcattgaggacaacgagtatacggccagagaaggcgcc
aagtttcctattaagtggacagccccagaagccattaactacgggacatttacaatcaaa
tctgatgtgtggtcttttgggatcctgctgacagagattgtcactcatggccgcatcccc
tacccagggatgacgaatcctgaagtgatacagaacttggaacgtggttaccgcatggtg
cgccccgacaactgcccggaagagctgtaccaactcatgaaactgtgctggaaagaacgc
ccagaggaacggcccacctttgactacctgcgtagtgtgctggaggacttcttcacggcc
acggagggccagtaccagccccagccttga
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