Ochotona princeps (American pika): 101523476
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Entry
101523476 CDS
T07609
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi01524
Platinum drug resistance
opi03440
Homologous recombination
opi03460
Fanconi anemia pathway
opi04120
Ubiquitin mediated proteolysis
opi04151
PI3K-Akt signaling pathway
opi05206
MicroRNAs in cancer
opi05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101523476 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
101523476 (BRCA1)
03460 Fanconi anemia pathway
101523476 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
101523476 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101523476 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
101523476 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101523476 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
opi01009
]
101523476 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
opi04121
]
101523476 (BRCA1)
03036 Chromosome and associated proteins [BR:
opi03036
]
101523476 (BRCA1)
03400 DNA repair and recombination proteins [BR:
opi03400
]
101523476 (BRCA1)
Enzymes [BR:
opi01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
101523476 (BRCA1)
Protein phosphatases and associated proteins [BR:
opi01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101523476 (BRCA1)
Ubiquitin system [BR:
opi04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
101523476 (BRCA1)
Multi subunit Ring-finger type E3
BRCC complex
101523476 (BRCA1)
Chromosome and associated proteins [BR:
opi03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
101523476 (BRCA1)
DNA repair and recombination proteins [BR:
opi03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
101523476 (BRCA1)
BRCA1-A complex
101523476 (BRCA1)
BRCA1-B complex
101523476 (BRCA1)
BRCA1-C complex
101523476 (BRCA1)
BRCA complex
101523476 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
101523476 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-C3HC4_4
zf-RING_UBOX
zf-RING_2
zf-C3HC4_3
zf-RING_5
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
Motif
Other DBs
NCBI-GeneID:
101523476
NCBI-ProteinID:
XP_004597451
LinkDB
All DBs
Position
19:complement(6379743..6442445)
Genome browser
AA seq
1838 aa
AA seq
DB search
MDLSGVHVEEVQNILNAMQKILECPICLELIKEPVSTRCDHIFCKFCMLKLLNQKRGPSQ
CPLCKNAITKRSLQESTRFSQLVEELLKIIQAFELDTGLPFASSYDFSKKKNNSPECQKD
EVSIIQSLGYRNRTKKLPKVESKNPALQDNSLSVQFCDLGIVRFPRTTQQTQPQNKSVYI
ELGSDSSEDTVNKTDCHSLENQISLQEDSAKATLDATEHDHAACLFSGKDTTNTEPLQSS
SKDLTTIKKHATERHPEKYQGTSISNLHVEPRGTNTHASSLQHENSSLLLTKDRTKVEKA
ELCDKSKPRGLARSQQGRWAESVKTYHDRQTPSTEGTEPLNVDSLCGRKQWKKQKPACPE
TCRDANSWLTVNSSIQKVNEWFSRSNVILTPDDSLGQQTESSAITTGTLQFSNKADGYSV
SSEKAGLLTSGSHNALVCESKRIHSKPVESTIKDKIFGKTYQRKASLPNLSRVIEDPVRE
VSAVEPQITHPPTNKLKRKRRATIGLCPEDFIKKVDLTGVEKTPKERNQGTEQMMQNDQV
MTITNGGNENETKGDHVQKEKSANPTESLEKESAFNTKAEPISSSISNMELELNIHKSKT
PKKNRLRRKSSTRRVHALELVVSEKPSPPNHTELQIDNCSSSEETNLGQVRVSRRRKLQV
IQDVTGTRKNKPNEQIRKRQASDASPEFKLANVPSVLTNCSSSKEHHESVDPSLQRGEVG
ENHDTVQASNTTTDPRGLPLSGERSMQAERSAESTSNSLIPDTDYDTQDSISLLEARTLR
NAKTAANGQESENVATGNPQEVAPAYLENTGDNPEGFKDPLRSEDDHIQETDTELEESEL
DTQYLQNTFKTSKRQSFALFSKPGDPERGCVTAHTHSSCLRNQSPKFSLECEQKEENPKK
EESKARHWQAVNSTVGFPVVCQKNKPGDYAKCSIKEISKLCLSSQFTGNETGLITANKHE
LLHNPYHIPPISPIKLTVKNTCELSPSEERSEEHSVSSERAVGSESIFYNTMSTISQNYM
KESARKEGGSSSVNEVSSSTNEVCSSINEVGSSGENIQAQPGRSRAPELNSVLRLSLVQP
GVCEQNLPINNSKLPEVKGPGENEVIQAVNSNFYSYLVSETQEPPIGNKNPSQICSETPD
DLLDDYDVMENTSFVDDGIRERSAVFSKSVQRGKISRTPSPLGHACLAQSHQSEAEKLES
KEENVSSEDEELISLQQLLYGKVTNRPPQSTRHSAVATEGLSVKSENLVLSENSFDDSSS
EIILPGASQEHDISEEIECSGSLFSSQHGAVEEVNENANSQDSFLMFDPLPKQTRHESEE
QQDVSDKELASDDDERANGPAEDNLQEQNVDANLGEAASGYESETSLSGVHSELSSQSEI
LTTQQRDAMQDNLLKLQQEMARLEAVLEQHGSQSPHTSPSLLALESCVPEDQLHLRQNTS
GKAILTSENHSESPVSHYPESLSVDKFPVSVHGSNSNNIGPAAERPSPSEVPGLDWPISS
CSSGLQNNNCPAPEGPAEDVGVEEQQLEKSEPQDSRSQSYLPTQETEGTSYLESGISLFD
DPEHSPEDRAPGPAPISTLKLPEFEVAEFSKGSATESAGYKAGKQSVRLGKPELASSTER
SDKAMSMVVSGLTSKEFSLVQKFAKKFHITLNNVITEETTHVIMKTDAEFVCERTLKYFL
GIAGGKWIVSYFWVIQSMKERKMLDEHGFEVRGDVINGRNHQGPKRARESQDRKIFKGLE
ICCYGPFTNMPTDQLEWMVQLCGASVVKELTSFTVGTDSHPVVVVQPDAWAEDDGFLAIG
QMCAAPVVTREWVLDSVALYQCQELEPYLIPQCHHSHC
NT seq
5517 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctggagttcatgtggaagaagtacaaaatatcctgaatgctatgcaaaaa
atcttagagtgtcccatctgtctggagttgattaaagaacctgtttccacaagatgtgac
catatattttgcaaattttgtatgctgaagctgctcaaccagaagagagggccttcacag
tgtcctttgtgtaagaatgccattactaaaagaagtctacaagagagtaccagatttagt
caacttgttgaagagctgttgaaaatcattcaggcttttgagcttgacacaggattacca
tttgcaagcagttatgacttttcaaaaaagaaaaataactcgcctgaatgtcaaaaggat
gaagtttccatcatccaaagtctgggctaccgaaatcgtaccaaaaaacttccaaaggtt
gagtccaaaaatcctgccttgcaggacaacagtcttagcgtccaattctgtgaccttgga
attgtgagattcccaaggacaacacagcagacgcagcctcagaataagtctgtctacata
gaactgggatcggactcttctgaagatacagttaataagacagattgtcacagtctggaa
aaccaaatcagccttcaagaagacagtgctaaagccactttggatgctacagaacacgat
catgctgcttgtctgttttctgggaaggacacaacaaatactgaacctcttcaatccagt
agcaaagatttgactaccattaagaagcatgcaaccgagaggcatccagaaaagtatcag
ggtacttctatttcaaacttgcatgtggagccacgtggcacaaacactcatgccagctca
ttacagcatgagaacagcagtttgttactcactaaagacagaacaaaagtagaaaaggct
gagctctgtgataaaagcaaaccgcgtggcttagcaaggagccaacagggcagatgggct
gaaagtgtgaaaacgtatcatgataggcagactcccagcacagagggaacagagcctctg
aatgttgattccctctgtgggagaaaacagtggaagaagcagaagcctgcctgccctgag
acctgtagagatgccaattcttggttaacagtaaatagcagcattcagaaagttaatgag
tggttctccagaagtaatgtgatattaactcctgacgactcacttggccaacagactgaa
tcaagtgccatcacgactggtacattacaattctcaaataaagcagatggatattcagtt
tcttcagagaaagcaggcttgctgaccagtggttcccataatgctttagtatgtgaaagc
aaaagaatccattccaaaccagtagagagtactatcaaagacaaaatatttgggaaaacc
tatcagaggaaggcaagcctcccaaacttgagccgcgtaattgaagatccagtgagagaa
gtatctgctgtagaaccacaaataacacatccccctacaaacaagttaaagcgtaaaagg
agagccactataggcctttgtcctgaagattttatcaagaaggtagatttgacaggtgtt
gaaaagactcctaaagagaggaatcagggaactgagcaaatgatgcagaatgatcaggtg
atgactattactaatggtgggaatgagaatgaaacaaaaggtgatcatgttcagaaagaa
aaaagtgctaacccaacagaatcattggaaaaagaatctgccttcaatacaaaagctgaa
cctataagcagcagtataagcaacatggaactcgaattaaatatccataaatcaaaaaca
cccaagaagaacaggctgaggaggaagtcctccaccaggcgtgttcatgcacttgagcta
gtcgtcagtgagaaaccaagcccacctaatcacactgaactacagatcgataattgtagt
agcagtgaagaaacaaatttgggccaagtacgtgtcagtcgcagaaggaagcttcaagtc
atacaagatgtcactggaaccaggaagaataagccaaatgaacaaataaggaaaagacag
gccagtgatgcttccccagaatttaagttagcaaatgtacccagtgttcttaccaactgt
tcaagttctaaggagcatcatgagtctgtcgatcctagccttcaaagaggggaagtagga
gagaaccatgatacagtccaagcatctaatactaccacagaccccagaggtctcccgtta
agtggagaaaggagcatgcaagctgaaagatctgcagagagcaccagtaactcacttatt
cctgacactgattatgatactcaggacagcatctcattactggaagctcgcacccttagg
aatgcaaaaactgcagcaaatggacaggagagtgagaatgtggcaactggaaatccccag
gaagttgccccagcttatttggaaaatactggagataatccagagggctttaaggacccg
ttgagaagcgaagatgaccatattcaagagacagacacagaactagaggagagtgagctt
gatactcagtatttgcaaaatacattcaagacttcaaagcgtcaatcatttgctttgttt
tcaaaaccaggagatccagaaaggggatgtgtaaccgcacatacccattccagttgctta
aggaaccaaagtccaaaattttctcttgaatgtgaacaaaaagaagaaaatccaaaaaag
gaagagtctaaagccaggcattggcaggcagttaattccactgtgggcttccccgtggtt
tgtcagaaaaataagccaggtgattatgccaaatgtagcattaaagaaatctctaagctt
tgtctgtcatcgcagttcacaggcaatgaaactgggctcatcacggcaaataaacatgaa
ctgttacacaacccatatcatataccaccgatttctcccatcaagttaactgttaaaaac
acatgtgagctaagcccgtcagaggaaaggtctgaggaacattcagtgtcctctgaaaga
gcagtgggaagtgagagcatcttttataatacaatgagtacaattagccagaattacatg
aaagaaagtgctcgtaaagaaggtggctcaagcagtgttaatgaagtgagttctagtact
aacgaagtatgctccagcattaatgaagtaggatccagtggggaaaacattcaagcacag
ccaggtagaagcagagcacctgagttaaactctgtgcttagattaagtcttgtgcaacct
ggtgtctgtgagcaaaatcttcccataaataattctaaacttcctgaagtaaaagggcca
ggagaaaatgaagtaattcaggctgtaaattcaaatttctattcatatctagtttcagag
acccaagagccacctataggaaataagaatccatctcagatttgttccgaaacacctgat
gatctgttagatgattatgacgtaatggaaaatactagctttgtggacgatggcattcgg
gaaagatctgctgtttttagtaaaagtgttcagagaggaaagatcagtaggacccctagc
cctttaggccatgcgtgtttggctcagagtcaccaaagtgaagctgagaaattggagtcc
aaagaagagaatgtgtccagtgaggatgaagagctgatttccctccaacaattgttgtat
ggtaaagtaaccaatagaccacctcaatcaaccagacatagtgctgttgccactgagggt
ctatccgtaaaatctgagaacttggtgttatcagagaacagcttcgacgactctagtagt
gagatcatactgccaggggcatcccaggaacatgacattagtgaggaaatagaatgttct
ggtagcttgttttcttctcaacatggtgcagtcgaagaggtgaatgaaaatgcaaactcc
caggattccttcctaatgtttgatcctcttcccaaacaaacgagacatgagtctgaagag
cagcaagatgtgagtgacaaggaattggcttctgatgatgacgaaagggcaaatggcccg
gcagaagataatctccaagaacagaatgtggatgcaaacttaggtgaagcagcatctggg
tatgaaagtgaaacgagtctgtctggagttcactcagaactgtcctctcagagtgaaatt
ttaaccactcagcagagggatgccatgcaagataacctgctcaagctgcagcaggaaatg
gctcgcctggaagccgtgctggagcagcacgggagccagtctcctcacacatccccttcc
ctgctcgcactggagtcctgtgtccctgaggatcagctccatctacgacagaacacatca
ggaaaagcaatattaacttcagagaatcatagtgaatctcctgtcagccattatccagaa
agcctttctgtggacaagttcccagtatccgtgcatggttccaacagcaacaatatagga
ccagcagctgaaagaccttctccttctgaagtccctggtttggactggcccatctctagc
tgttctagcggtcttcagaacaataactgcccagctccagaagggcccgctgaggatgtt
ggtgtggaagaacagcagctggaaaagtcagagccgcaagattcaaggtcacagtcttat
ttgcccacacaagagacagagggcacctcctatttggaatctggaatcagcctctttgat
gaccccgaacattctcctgaggatagagcccctgggccagctccaatatctacattgaaa
ttacctgagtttgaagttgcagaattttccaagggttcagctactgagagcgctgggtac
aaagcaggaaaacaaagtgtgaggctgggtaagccagagctggcatcctcaacagaaagg
agcgacaaagcaatgtccatggtagtgtcgggcctgacctcaaaagagttttcactggtg
caaaagtttgccaagaaattccacatcactctaaataatgtaattaccgaagagactact
catgtcattatgaaaacagatgctgaatttgtgtgtgaacggacactgaaatattttctg
ggaattgcaggaggaaaatggatagttagctatttctgggtgatccagtctatgaaagaa
agaaagatgcttgatgagcatggctttgaggtcagaggagatgtaatcaatggaagaaac
caccaaggtccaaagcgagcgagagaatcccaggacagaaagatcttcaagggcttagaa
atctgttgctacgggccctttaccaacatgcccacagatcaactggagtggatggtgcag
ctctgtggcgcttctgtggtgaaggaacttacgtcattcaccgtaggcacagattcccac
ccagtcgtggtcgtgcagccagatgcctgggcagaggacgatggcttcctcgccatcggg
cagatgtgtgcggcccctgtggtgaccagagagtgggtgttggacagcgtagccctctac
cagtgccaggagctggagccttacctgataccacagtgccaccacagccactgctga
DBGET
integrated database retrieval system
