Ochotona princeps (American pika): 101530887 Help Entry 101530887         CDS       T07609                                  Symbol INSR Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism opi  Ochotona princeps (American pika) Pathway opi04010   MAPK signaling pathway opi04014   Ras signaling pathway opi04015   Rap1 signaling pathway opi04022   cGMP-PKG signaling pathway opi04066   HIF-1 signaling pathway opi04068   FoxO signaling pathway opi04072   Phospholipase D signaling pathway opi04150   mTOR signaling pathway opi04151   PI3K-Akt signaling pathway opi04152   AMPK signaling pathway opi04211   Longevity regulating pathway opi04213   Longevity regulating pathway - multiple species opi04520   Adherens junction opi04910   Insulin signaling pathway opi04913   Ovarian steroidogenesis opi04923   Regulation of lipolysis in adipocytes opi04930   Type II diabetes mellitus opi04931   Insulin resistance opi04932   Non-alcoholic fatty liver disease opi04960   Aldosterone-regulated sodium reabsorption opi05010   Alzheimer disease opi05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:opi00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101530887 (INSR)    04014 Ras signaling pathway     101530887 (INSR)    04015 Rap1 signaling pathway     101530887 (INSR)    04066 HIF-1 signaling pathway     101530887 (INSR)    04068 FoxO signaling pathway     101530887 (INSR)    04072 Phospholipase D signaling pathway     101530887 (INSR)    04022 cGMP-PKG signaling pathway     101530887 (INSR)    04151 PI3K-Akt signaling pathway     101530887 (INSR)    04152 AMPK signaling pathway     101530887 (INSR)    04150 mTOR signaling pathway     101530887 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     101530887 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101530887 (INSR)    04923 Regulation of lipolysis in adipocytes     101530887 (INSR)    04913 Ovarian steroidogenesis     101530887 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101530887 (INSR)   09149 Aging    04211 Longevity regulating pathway     101530887 (INSR)    04213 Longevity regulating pathway - multiple species     101530887 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     101530887 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     101530887 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101530887 (INSR)    04932 Non-alcoholic fatty liver disease     101530887 (INSR)    04931 Insulin resistance     101530887 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:opi01001]     101530887 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:opi04090]     101530887 (INSR) Enzymes [BR:opi01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      101530887 (INSR) Protein kinases [BR:opi01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    101530887 (INSR) CD molecules [BR:opi04090]  Proteins   101530887 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like fn3 Insulin_TMD Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  101530887 NCBI-ProteinID:  XP_004595784 LinkDB All DBs Position Unknown AA seq 1372 aa AA seqDB search MGAGGRRGAAATPLLAAVAALLLGAAGHLYPGEVCPSMDIRNNLTRLHELDNCSIIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLRDLFPNLTVIRGSRLFFNYAL VIFEMVHLKDVGLPSLMNITRGAVRIEKNNELCYLSTIDWSRILDSVEDNYIMLNKDDKE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTACKSHGCTAEGLCCHSECL GNCTEPDDPTKCTVCRNFYLEGRCVDTCPPPYYNFQDWRCVTFNFCQELHNRCRNSRRQG CHQYVIHNNRCLPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWGKHNLTISRGKLFFHYNPKLCLSEIHRMEEVSGTKGRQD KNDIALKTNGDQASCENELLKFSSIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIEPPLRSNDPKSQSHPGFLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQILLKWKPPSDPNGNITHYLVYWE QQEEDQELFELDYCLKGLKLPSRTWLPQFESEHAQKHNQSEAEVASGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRPSRKRRSLGDGDSNVTIVAVPTLPEFDNITSTGMPT TPEVLRPFEKVINKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVSARTMPEAKA DDIVGPVTHEIFENNVVHLTWREPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFAQERG CRLRGLSPGNYSVRVRATSLAGNGSWTEATYFYVADYLDVPTNIAKIIIGPLIFVFLFSV VIGSIYLFLRKRHPDGPMGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELG QGSFGMVYEGNAKDIIKGEAETRVAVKTVNEAASLRERIEFLNEASVMKGFTCHHVVRLL GVVSKGQPTLVIMELMTHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMSAEIADGMAYL NAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKD GVFTTFSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGHLEQPDNCPERLNDLMR LCWQLNPKMRPTFLEVVSLLQDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLD RSSHSQREEAAGREGGTSLAVKRSYEDHIPYTHMNGGKKNGRILSLPRSNPS NT seq 4119 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggccggcggggggcggcggccacgccgctgctggcggctgtggccgcg ctgctgctgggcgccgcgggccacctgtaccctggagaggtgtgccccagcatggacatc cggaacaacctcaccaggttacacgagctggacaactgctccatcattgagggccacctg caaatcctgctcatgttcaagacaaggcccgaagacttccgggatctcagcttccccaag ctcatcatgatcaccgactacttgttgctcttccgggtctacggcttggagagcctccgc gacctgttccccaacctcacggtcatccgcggctcccggctcttcttcaactatgcgctg gtcatcttcgagatggtgcatcttaaagatgtggggctgcccagcctcatgaacatcacg cggggcgccgtgcgcatcgagaagaacaacgaactctgttacctgtccaccatcgactgg tcccgcatcctggactcggtggaggacaattacatcatgctcaacaaggatgacaaagaa gaatgcggggacatttgtcccgggactgccaagggcaagaccaactgccctgccactgtc atcaacgggcagtttgtcgagcgctgctggacgcacagccactgccagaaagtgtgcccg accgcctgcaagtcacacggctgtactgccgagggcctctgttgtcacagcgagtgcctg ggcaactgcaccgagcccgacgaccccaccaagtgtaccgtgtgtcgcaacttctacctg gaaggccgctgcgtggacacctgcccgccaccctactacaacttccaggactggcgttgt gtaacctttaacttctgccaggagttgcacaacaggtgcaggaactcgcggaggcagggc tgccaccagtacgtcatccacaacaacaggtgcctccccgagtgcccctcgggctacacc atgaactccagcaacttgatgtgcacgccgtgcctgggtccctgtcccaaggtgtgccac ctgctggaaggcgagaagaccatcgactcggtgacgtccgcccaggagctccgcggctgc accattatcaacggcagtttgattatcaacatccggggtggcaacaacctggcggctgag ctagaagccaacctgggcctcattgaagagatttccggatatctcaaaatccgccgctcc tacgctttggtgtcgctttccttcttccggaaattacgtctgattcgcggggagaccctg gaaatcggcaactactccttctatgccctggacaaccaaaacctgcggcagctgtgggac tggggcaaacacaacctcaccatctcccggggcaagcttttcttccattacaaccccaag ctgtgcctgtcggagattcataggatggaggaagtatctggcaccaaggggcgccaggac aagaatgacatcgccctgaaaaccaatggggaccaggcttcctgtgaaaacgagttactt aaattttcttccatccggacaagctttgacaagatcttgctgaggtgggagccctactgg ccccccgacttccgagacctcctggggttcatgctcttttacaaagaggccccctaccag aacgtgacggagttcgacgggcaggacgcgtgtggctccaacagctggaccgtggtggac atcgagccacccctgagatccaacgaccccaagtcgcagagccatcccgggtttctgatg cgcggcctcaaaccctggacccagtatgccatcttcgtgaagacccttgtcaccttctct gatgagcgccggacctacggggctaagagtgacatcatctacgtgcaaacggacgccacc aatccgtccgtccccctggacccgatctccgtttccaattcctcgtcccagatcctactc aagtggaagccgccctcggaccccaacggcaacatcacgcactacctggtctactgggaa cagcaggaggaggatcaggaactgttcgagctggactattgcctcaaggggctgaagctg ccctcccgcacgtggttgccgcagtttgagtccgagcacgcgcagaaacacaaccagagt gaggcggaggtggcgtcgggcgagtgctgctcctgccccaagaccgactcgcagatcctg aaggagctggaggagtcgtccttccgcaagaccttcgaggactacctgcacaatgtggtg ttcgtgcccaggccgtcaaggaagcgcaggtctctcggtgatggggacagcaacgtgaca atagtggccgtgcccacgctcccggaattcgacaatatcacgtccactgggatgcccacc accccagaagtgctcagacccttcgagaaggttatcaacaaggagtcgctggtcatctcc ggcctgcgccacttcactggctaccgcatcgagctgcaggcctgtaaccaggacgcgccg gaggagcgctgcagcgtggccgcctatgtcagcgcgcggaccatgccggaagccaaggct gatgacatcgttggtcccgtaacccatgagatctttgagaacaatgtggttcacctgacg tggcgagagcccaaggaacccaacgggctgatcgtgctgtatgaagtgagctatcggcgc tacggtgacgaggagctacacctctgcgtctcccgcaagcatttcgctcaggagcggggc tgccggctacggggtctgtccccggggaactatagtgtacgggtgcgggccacctccctg gcgggcaacggctcgtggaccgaagccacctacttctatgtggccgactacctagatgtc ccaacgaatattgcaaagattatcatcggccccctcatctttgtctttctcttcagtgtc gtgattggaagtatttacctcttcctgaggaaaaggcatccagacgggcccatggggccg ttgtacgcctcttcaaaccccgagtacctcagtgccagcgatgtatttccatgttctgtg tacgtcccggatgagtgggaggtgccgcgagagaagatcaccctcctgcgggagctgggc cagggctccttcggcatggtgtacgaaggcaacgccaaggacatcatcaagggcgaggca gagactcgcgtggccgtgaagaccgtcaacgaagcagccagcctgcgggagcgcatcgag ttcctcaatgaggcctctgtcatgaagggtttcacctgtcaccacgtggtgcgcctcctg ggtgtggtatccaagggccagcccacgctggtgataatggagctgatgacccatggagac ctcaaaagttatctccgttccctgcgacccgaggctgagaacaaccccggccgccctccc ccgaccctgcaagagatgattcagatgtcggccgagattgcggacggcatggcctacctc aatgccaagaagtttgtgcaccgtgacctggcggctcggaactgcatggtggcccacgac ttcactgtcaagatcggagattttggaatgaccagagatatctacgagacggactactac cgtaagggaggcaagggcctgctgcccgtgcgctggatggctcccgagtccctcaaggac ggagtgttcaccaccttctctgacatgtggtctttcggcgtggtcctctgggagatcacc agcctggcagagcagccctaccaaggtctgtccaatgagcaggtgcttaagtttgtcatg gatggcggacacttggaacaacctgacaactgcccggagagactcaacgacctgatgcgc ctgtgctggcagctgaaccccaagatgcggcccaccttcctggaggttgtgagcctgctg caggatgacctgcaccccagcttcccggaggtctccttcttccacagcgaagagaacaag gccccagagagcgaggagctggagatggaatttgaggacatggagagcgtcccgctggac cgctcctcgcacagtcagagggaggaggcggctggccgggaaggggggacctctctggcc gtcaagcgcagctacgaagaccacatcccttacacccacatgaacgggggcaagaagaac gggcggattctgagcctgcctcgctccaatccctcctaa

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