Odobenus rosmarus divergens (Pacific walrus): 101363371
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Entry
101363371 CDS
T05148
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro04010
MAPK signaling pathway
oro04014
Ras signaling pathway
oro04015
Rap1 signaling pathway
oro04022
cGMP-PKG signaling pathway
oro04066
HIF-1 signaling pathway
oro04068
FoxO signaling pathway
oro04072
Phospholipase D signaling pathway
oro04150
mTOR signaling pathway
oro04151
PI3K-Akt signaling pathway
oro04152
AMPK signaling pathway
oro04211
Longevity regulating pathway
oro04213
Longevity regulating pathway - multiple species
oro04520
Adherens junction
oro04910
Insulin signaling pathway
oro04913
Ovarian steroidogenesis
oro04923
Regulation of lipolysis in adipocytes
oro04930
Type II diabetes mellitus
oro04931
Insulin resistance
oro04932
Non-alcoholic fatty liver disease
oro04960
Aldosterone-regulated sodium reabsorption
oro05010
Alzheimer disease
oro05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101363371 (INSR)
04014 Ras signaling pathway
101363371 (INSR)
04015 Rap1 signaling pathway
101363371 (INSR)
04066 HIF-1 signaling pathway
101363371 (INSR)
04068 FoxO signaling pathway
101363371 (INSR)
04072 Phospholipase D signaling pathway
101363371 (INSR)
04022 cGMP-PKG signaling pathway
101363371 (INSR)
04151 PI3K-Akt signaling pathway
101363371 (INSR)
04152 AMPK signaling pathway
101363371 (INSR)
04150 mTOR signaling pathway
101363371 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
101363371 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101363371 (INSR)
04923 Regulation of lipolysis in adipocytes
101363371 (INSR)
04913 Ovarian steroidogenesis
101363371 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
101363371 (INSR)
09149 Aging
04211 Longevity regulating pathway
101363371 (INSR)
04213 Longevity regulating pathway - multiple species
101363371 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101363371 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101363371 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101363371 (INSR)
04932 Non-alcoholic fatty liver disease
101363371 (INSR)
04931 Insulin resistance
101363371 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oro01001
]
101363371 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
oro04090
]
101363371 (INSR)
Enzymes [BR:
oro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101363371 (INSR)
Protein kinases [BR:
oro01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
101363371 (INSR)
CD molecules [BR:
oro04090
]
Proteins
101363371 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
B2
DUF4476
Motif
Other DBs
NCBI-GeneID:
101363371
NCBI-ProteinID:
XP_004412234
UniProt:
A0A2U3WSM4
LinkDB
All DBs
Position
Unknown
AA seq
1381 aa
AA seq
DB search
MGAGAGRGAATAPLLVAVAALLLGATGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSQCL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNRCKNSRRQG
CHQYAIHNSKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC
TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQVEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRKSSSSPGAENTRPSRKRRALGDVANVTAAAPTVPGF
PNTSTSAPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVS
ARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVS
RRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGP
LIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE
KITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGF
TCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAA
EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR
WMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNC
PERVTDLMHMCWQFNPKMRPTFLEIVELLKDDLHPSFPEVSFFHSEENKAPESEELEMEF
EDMESVPLDRASHSQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNP
S
NT seq
4146 nt
NT seq
+upstream
nt +downstream
nt
atgggcgccggggctgggcggggggcggcgaccgcgccgctgctggtggcggtggccgcg
ctgctgctgggtgccacgggccacctgtacccgggagaagtgtgccctggcatggatatc
cggaacaacctcacgaggttgcatgagctggccaactgctcggtcattgaaggacatttg
cagatactgttgatgttcaaaacgaggcccgaggatttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag
gacctgttccccaacctcacggtcatccggggctcgcgtctcttcttcaactatgcgctg
gtcatcttcgagatggttcacctgaaggagcttggcctctacagcttgatgaacattacc
cggggctctgtccgcattgagaagaacaatgagctctgctacctggccaccattgactgg
tcgcgcatcctggattctgtggaggataattacattgtgctgaacaaagacgacaacgag
gagtgtggggacatttgtccaggcactgcaaagggcaagaccaactgccccgccactgtc
atcaacgggcagtttgtcgagcggtgttggacacacagccactgccagaaagtttgtccc
accatctgcaagtcacacggctgtaccgccgagggtctctgctgccacagccagtgttta
ggcaattgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg
gatggcaggtgcgtggagacctgcccgcccccgtactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacagatgcaagaactcccggagacagggc
tgccaccagtatgccattcacaatagcaagtgtatccctgagtgcccctctggctacacg
atgaattccagcaacctgatgtgcactccatgcctgggcccctgtcccaaggtctgccac
atcctggagggcgagaaaaccattgactcggtgacgtctgcccaggagcttcgaggctgc
actgttgtcaacggaagcctcatcatcaacatccgagggggcaacaacctggcagctgag
ctggaggccaacctaggactcattgaagaaatttctgggtatctgaaaatccggagatcc
tacgctcttgtgtcactttcttttttccggaagttacggctgattcgaggagaaaccttg
gaaatcgggaactactctttctacgccttggacaaccagaacctaaggcagctctgggac
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactacaatcccaaa
ctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
aggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactcctt
aaattttcttacattcggacatcgtatgacaagatcttgctgaaatgggagccgtactgg
ccccctgacttccgagacctcctggggttcatgcttttctacaaagaggccccttaccag
aatgtgactgagttcgacgggcaggatgcgtgtggttccaacagctggacggtggtggac
attgacccacctctgcggtccaacgaccccaagtcgcagaaccacccagggtggctgatg
cggggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttct
gatgaacgccgcacgtatggggccaagagtgatatcatctatgtacagacggatgccact
aacccttccgtccccctggatccaatctccgtttctaactcctcgtcccagattattctg
aagtggaagcctccctctgatcccaatggcaacatcacacactatctggttttctgggag
aggcaggtggaagacagtgagctgtatgagctggattactgcctcaaagggttgaaactg
ccatcccggacctggtctccgccgttcgaggccgagggctcccagaagcacaaccagagt
gaatacgaggagtctgccggcgaatgttgctcctgccccaagacggactctcagatcctc
aaggagctggaggagtcctcttttaggaagacctttgaggattacctgcacaatgtggtg
ttcgtccccagaaaatcctcttcaagccctggtgctgagaacactaggccatcgcggaaa
cgccgggccctcggggacgttgccaatgtgacggcagccgcgcccacggttccaggtttc
cccaacacctcgaccagcgcgcccacgagcccggaggagcacaagcccttcgagaaagtg
gtgaacaaagaatccctggtcatctctgggctgcgccacttcactggctaccggatcgag
ctgcaggcttgcaaccaagactcccccgaggagaggtgtagcgtggcggcctacgtcagc
gccaggaccatgcctgaagccaaggcagatgacattgttggccccgtgacccacgaaatc
ttcgagaacaatgtcgttcacttgatgtggcaggagccaaaggaacccaacggtctgatc
gtgctgtatgaagtgagttaccgacggtatggtgatgaggagctgcacctctgtgtctcc
cgcagacattttgctctggagcggggctgcaggctgcgcgggctgccgccagggaattac
agcgtgcgagtccgggccacctccctggcaggcaacggctcatggacagaagctacctat
ttctacgtgacagactatttagatgtcccgtcgaatattgcaaaaatcatcatcggcccc
ctcatctttgtctttctcttcagtgttgtgattggaagtatttacctgttcctgagaaag
aggcagccggatgggccactgggaccgctgtatgcgtcttcaaaccctgagtacctcagt
gccagtgatgtctttccatgttctgtgtatgtgccggacgagtgggaggtgcctcgggag
aagatcacgctcctgcgtgagctggggcagggctccttcggcatggtgtacgaaggcaac
gccagggacatcgtcaagggcgaggcagagacccgcgtggcggtgaagacagtcaacgag
tcggccagtctgcgggagaggatcgagtttctcaacgaggcctcagtcatgaagggcttc
acctgtcatcacgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctggtg
gtgatggagctgatggctcacggcgacctgaagagctaccttcgctccctgcggccagag
gctgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggcggcg
gagatcgccgatgggatggcctacctgaatgccaagaagtttgtgcaccgggatctcgca
gcccgaaactgcatggtcgcccacgatttcactgtcaaaattggagactttgggatgacc
agagacatctatgaaacggattactaccggaaaggaggcaagggtctgctccccgtgcgg
tggatggcaccggaatccctgaaggacggggtctttaccacttcttctgacatgtggtcc
ttcggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctgtct
aatgaacaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaattgt
ccagagagagtcactgatctgatgcatatgtgctggcagttcaatcccaagatgcggccc
accttcctagagatcgttgaactgctcaaggacgacctgcaccccagctttccagaagtt
tccttcttccacagcgaggagaacaaggcacctgagagcgaggagctggagatggagttc
gaggacatggagagtgtccccctggatcgggcctcacactctcagagggaggaggccggg
ggccgggatggagggtcctcgctgggcctaaaacggaactacgaggagcacatcccctac
acccacatgaacgggggcaagaaaaacggacggattctgactctgccgaggtcaaatcct
tcctaa
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