Odobenus rosmarus divergens (Pacific walrus): 101366843
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Entry
101366843 CDS
T05148
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro00310
Lysine degradation
oro01100
Metabolic pathways
oro05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
101366843 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101366843 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
oro03036
]
101366843 (DOT1L)
Enzymes [BR:
oro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
101366843 (DOT1L)
Chromosome and associated proteins [BR:
oro03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
101366843 (DOT1L)
HMT complexes
Dot1-containing complex
101366843 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
101366843
NCBI-ProteinID:
XP_004395445
UniProt:
A0A2U3VKW2
LinkDB
All DBs
Position
Unknown
AA seq
1705 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDNKSTTATPTKLP
ESKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALRTQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDALSAHLRGKGALGRELEADPGRLHLDLDCSKFSLSHLSSASPELSMNGHAASY
EVCGALSRPSSKQNTPQYLASPLDQEVIPCTPSHSSRPRLEKMSGLALPDYTRLSPAKLV
LRRHLSQDHVASGKTAASELHPRAEHAKENGLPYQSPGIANGIKLSPQDPRPSSPMALQM
TGERGGEKGVKERAYASTGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGANAHGAGSKGLTPAPAGFYAGSVAVSGALAGSPAPLAPGAE
PGTFDDVSGSGSLFASMGSCSTPQHPPLLPQSRSSGAASPAHPLCTSPRLSSAAQGPLPE
ANKGDLPSEAGFSDPEGEAKRRIVFTISAGGSAKQSPPGKPSPLPTGARGDSGQGHGPDS
RKRGRRKRAAAGTPSLSAGVSPKRRALPSVAGLFTQSSGSPLNLSSMVSNINQPLEITAI
SSPESLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSARIERKI
ATISLESKSPPKTLESGGGLAGRKPTPASEPANSSKWKSTFSPISDLGLAKCADSPLQAG
STLSQNSLFTFRPPLEEPGLADAKLAAHPRKSFSGALSGAGGLSPSSNPPNGFAFSGGLA
TDLSLHSFSDGASLSHKVPEAASLGAPLSFPAPRGKEGGAAEPGAFVNKRQLDGLGGPKG
REAGELGLPACGPPDKASLVHSKPGKGRDREPDLKNGHNLFISAATVPPGGLLSGPGLAT
AASSAVSAAPSAQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVPAAAGLVHV
SSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSATLSLTP
LQAVAGAPASSFQAPPPPPPGQPALPAPPPPNAALPPAPALLPANSEPVLLQNLASLPAN
QAFLSTSSAASLQPANASLSIKLASLPHKAPRPSFTVHHQPLPGLALAQAAPVIPQASST
GPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5118 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccggtgggtctgtgaagagatcccagacctcaagcttgctatggagaattacgttctg
atcgactatgacaccaaaagcttcgaaagcatgcagaggctctgtgacaaatacaaccgc
gccatcgacagcatccaccagctgtggaaggggaccacgcagcccatgaaactgaacact
cggccgtccaacgggctcctgcggcacatcctgcagcaggtctacaaccactcggtgacg
gaccctgagaagctcaacaactacgagcccttctcccccgaggtgtacggggagacctcc
tttgacttggtcgcacagatgatcgatgagatcaagatgaccgaggacgacctgtttgtg
gacctgggcagtggagtgggccaggtcgtgctgcaggtcgccgcggccaccaactgcaaa
catcactatggcgtagagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggcgacttcctctcggaagagtggagagagcggattgccaacacaagtgttatatttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcgaacatg
aaggaaggtggcagaatcgtgtcctcgaagccctttgcgcctctgaacttcagaataaac
agcagaaacttgagtgacattggcaccatcatgcgcgttgtggagctctcgcccctgaaa
ggctcggtgtcctggacggggaagccggtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaagcg
gcccggcgccggcagcagcgagacaacaagagcaccacggccactcccaccaagctgccc
gagagcaaggccgccgtgcccgcggacaccccgatggattccggggccgaggaagaaaaa
gctggggcgaccaccatcaaaaagccgtccccctccaaagcccggaagaagaagctgaac
aagaaggggcggaagatggccggccggaagcgcgggcgtcccaagaagatgagcactgcg
aacccggagcgtaagcccaagaagagccaaactgcactggacctcctgcatgcccaggcc
gcgtcacagacggcagcgccctcgccgcaggatgcgtacaagtcacctcatagcccgttt
tatcagctacctcccagtgtgcagcggcacccccccgaccagctgctgctggcacccacc
ccgcccgcactgcagaagctgctagaatccttcaagattcagtacttgcagttcttggca
tacaccaagaccgcccagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaacgcccggttgctaggtgctgcacagcagctgttcggccactgccaggcccagaaa
gaggagatcaagaggctcttccagcagaaactggatgagctgggtgtgaaggcactgacc
tacaatgacctgatccaggcgcagaaggagatttcggctcacaaccaacagctgagggaa
cagacggagcagctgcagaaggacaacagggagctgagaagccagagcctgcagctgctc
aaggctcggtgtgaggagctgaagctggactggtccacgctgtccctggagaacttgctg
aaggagaagcaggccctgaggacccagatctctgagaagcagaggcactgcctggagctg
cagatcagcattgtggaactggagaagagccagcggcagcaggagctcctgcagctcaag
tcttgcgtgccgccggatgacgccctgtcggcgcacctgcgcgggaaaggagccctgggc
cgggagctggaggctgaccccggccggctgcatctggacctggactgctccaagttctcc
ctgtcccacttgagcagcgcaagcccagaactctccatgaacggccacgcggctagctac
gaagtgtgcggtgcgctgagccggccctcgtccaagcagaacaccccccagtacctggcc
tcccccctggaccaggaagtcataccctgcacccccagccacagcagccggccgaggctc
gagaagatgtcgggcctggccttgcctgactacacccggctctccccggccaagctggtg
ctgaggcggcacctgagccaggaccacgtggccagtggaaagacggcggccagtgagcta
cacccgcgagctgagcacgccaaggagaacggccttccataccagagccctggcattgca
aacggcatcaagctgagtcctcaggaccctcgaccctcgtcccccatggccttacagatg
acaggggagaggggcggcgagaagggtgtgaaggagcgcgcctatgccagcactggggag
gccatcaccagcctgcccgtcagcatcccgctcagcaccgtgcagccgagcaagctgccc
gtcagcatccctctggccagtgtggtgctgcccagccgtgccgagaaagtgagaagcacc
cccagccctgtgccgcagacccgagagtcctcgtccacacttgaaaagcagatgggcgct
aatgcccacggcgctggaagcaaaggcctcaccccagctcctgcaggcttctacgcgggc
tcagtggctgtcagcggggccctggcaggcagcccggcccccctcgctcccggagctgag
cccggcaccttcgatgacgtctcgggctcaggaagtctgttcgccagcatggggtcctgc
tccaccccgcagcacccgcccctgctaccgcagtcccgcagctccggcgcagcctcgcct
gcccatccgctctgcaccagcccgcggctcagcagtgctgcccagggcccgctccccgag
gccaacaaaggggaccttccttccgaggccggcttttcagacccagagggcgaagccaag
aggaggatcgtctttaccatctcggctggcggcagtgccaaacagtcgcctcccggcaaa
ccgagccctctgcccacgggcgcccgcggggacagtggccagggccatgggccggacagc
cgcaagcggggcaggaggaagcgggcggcggctgggacccccagcctgagcgctggcgtg
tcgcccaagcgccgggccctgccgtccgttgccggcctcttcacgcagtcttcggggtcc
ccgctgaacctcagctctatggtcagcaacattaaccagcctttggaaatcacggccatc
tcgtcccccgagagcctgaagagctcccctgtcccttaccaggacaacgaccagccgccc
gttctcaagaaggagaagccgttgagccagaccaacggggcccactactccccactgacc
tcagacgaagagcagggctctgaggatgagccaggcagcgccagaatcgagagaaaaatt
gcaacaatctccttagaaagcaaatctcctccaaaaaccttggaaagcggtggtggcctg
gccgggaggaagccgacccctgccagcgagcccgccaacagcagcaagtggaaatccacc
ttctcgcccatttccgacctcggcctggccaagtgcgccgacagcccgctgcaggctggc
tccaccctgagccagaactccctgttcactttccggcccccgttagaggagcccggcttg
gctgatgccaagctggctgcccaccccaggaaaagcttttctggtgccctgtcgggggcc
ggtgggctgagccccagcagcaaccctcccaacggcttcgccttcagcgggggcctggcc
accgacctcagtttacacagcttcagcgatggtgcttctctctcccacaaggtccccgag
gcggccagcctgggcgcccccctgagcttccctgccccgcggggcaaggagggcggtgcc
gcagagcccggcgcctttgtgaacaagaggcagctggacggactgggcggccccaagggc
agggaggccggcgagctgggcctgccggcgtgcgggcccccggacaaggcctcgctggtg
cacagcaagccgggcaagggccgggaccgcgagcccgacttgaagaatggccacaacctc
ttcatttctgccgccactgtgcctcccgggggcctcctcagcggcccgggcctcgccacg
gcggcgtcctcggcggtcagcgcggccccctccgcccagacacaccgccccttcctgggc
acctttgcccccggcccacagttcgccctgggtcccatgtccctgcaggccaacctgggc
tcatccgtgctacagtccttgttcagttccgtgccggccgctgccggcctggtgcacgtc
tcgtccgctgcaaccagactgaccaactcgcacgccatgggcagcttttcctccggggtg
gcaggtggcgcagttggaggtgtctttaaccacgcggtgccttccgcctccgctcatccg
tttggagccagtttcggcagcggggctgcgtgtcgcagcgccacgctgagcttaacccca
ctgcaggcggtggccggcgcccccgcgtcttcctttcaggccccgcccccgcccccaccg
gggcagcccgccctccctgcaccccctccccctaacgccgccttgcctcctgcccccgcg
ctgctcccggctaactctgagcccgtgcttctgcagaacctcgcgtccctcccggctaac
caggctttcttatccacctcctctgccgcctctctgcagcctgctaacgcctctctgtcc
atcaagctcgcctccctcccgcacaaggccccccgcccctccttcacggtgcaccaccag
cccctgcccgggctggccctggcccaggccgcgcccgtgatcccgcaggccagctccacg
gggccgtctgccgtgtgggtttcccttggcatgccgcctccgtatgccgcgcgccttgcg
ggggttaagccaagataa
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integrated database retrieval system
