Pyrococcus abyssi: PAB0891
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Entry
PAB0891 CDS
T00024
Symbol
leuC-1
Name
(GenBank) leuC-1 3-isopropylmalate dehydratase large subunit (isopropylmalate isomerase) (EC 4.2.1.33)
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
pab
Pyrococcus abyssi
Pathway
pab00290
Valine, leucine and isoleucine biosynthesis
pab00660
C5-Branched dibasic acid metabolism
pab01100
Metabolic pathways
pab01110
Biosynthesis of secondary metabolites
pab01210
2-Oxocarboxylic acid metabolism
pab01230
Biosynthesis of amino acids
Module
pab_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PAB0891 (leuC-1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PAB0891 (leuC-1)
Enzymes [BR:
pab01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PAB0891 (leuC-1)
4.2.1.35 (R)-2-methylmalate dehydratase
PAB0891 (leuC-1)
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Paralog
Gene cluster
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
CAB50255
UniProt:
Q9UZ07
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Position
1306942..1308213
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AA seq
423 aa
AA seq
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MGMTIAEKILADHSEREEVKPGEIVMAKLDFVFGNDVTMPLAIKKFRELGVKRVFDRERI
AIVLDHFTPNKDIKSAEQCKSSREFAKEMGIKWFFEGGSVGVEHCLLPELGLVLPGDLII
GADSHTCTYGALGAFATGVGSTDLAVAMATGEAWFRVPETMKFIYEGELQPYVTGKDLIL
HTIGDIGVNGALYKVMEFSGSVIEELSVEQRMTMSNMAIEAGAKTGIIEPDKKTLDYVKE
RAKRKFKVYKSDEDAKYYKVIEYDVTNWEPVVAFPHLPENTVPISKAAKMNIKIDQVFIG
SCTNGRIEDLRMAAEILEGQKVAKWVRLIVIPCSPTVYWKALKEGLIEIFLEAGAVIGPP
TCGPCLGGHMGVLASGERAVSTTNRNFVGRMGHPKSEVYLANPYVAAASAVLGRIASPEE
VVK
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgacgatagctgagaagattttagcagatcactccgaaagggaggaggttaaa
cctggagaaatagtcatggccaagttggatttcgtgtttggaaacgatgtaacgatgcct
ctagctataaagaagtttagggaacttggagttaagagggttttcgatagggaaaggata
gcgatagttctagatcacttcacgccaaacaaggatataaagagcgccgagcagtgcaaa
tcttcaagggagttcgccaaagagatgggaataaaatggtttttcgaaggaggaagtgtc
ggagttgaacactgcttacttccagagctaggtcttgttcttcctggagacttaattatc
ggtgcagattcgcacacatgcacgtatggtgctctcggtgccttcgcaacaggagttggg
agtactgatttagccgtcgcgatggctactggggaagcctggttcagggttcccgaaacc
atgaaattcatctacgagggagagctccaaccttatgtaactggtaaggatttgatcctt
cacacaatcggagatataggagtaaatggagccctatacaaggtcatggaattcagtgga
agcgtaatagaggagctctcggtggaacagaggatgaccatgagtaatatggctatagaa
gctggagcaaagactgggataatagaaccggataagaaaaccctagattacgttaaggag
agagcaaaaaggaagtttaaggtttacaaaagcgacgaggatgctaagtactacaaagtt
atcgagtacgacgttaccaactgggaacctgtagttgcctttccccatttaccggagaac
acggttccaataagtaaggctgcaaagatgaacataaagatagatcaggtcttcataggt
tcttgcacaaatgggagaatagaagatctaagaatggcggctgaaattttagaagggcaa
aaagtcgccaagtgggttaggttaatcgtcattccgtgctctccaacggtttactggaaa
gccttgaaggaaggtttgatagagatattcttggaggccggagctgtaataggacctccc
acgtgtggaccctgtctcggaggtcacatgggagtgcttgcaagtggtgaaagggctgtc
tctacaactaacaggaacttcgttgggagaatggggcatccaaagagcgaggtttactta
gctaacccatacgtcgccgctgcttcagctgttttgggtaggatagcatccccagaggag
gtggtaaaatga
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