Pseudoalteromonas agarivorans: PAGA_a0125
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Entry
PAGA_a0125 CDS
T06137
Symbol
hemDX
Name
(GenBank) uroporphyrinogen III methyltransferase / synthase
KO
K13543
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
paga
Pseudoalteromonas agarivorans
Pathway
paga00860
Porphyrin metabolism
paga01100
Metabolic pathways
paga01110
Biosynthesis of secondary metabolites
paga01120
Microbial metabolism in diverse environments
paga01240
Biosynthesis of cofactors
Module
paga_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
paga_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:
paga00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
PAGA_a0125 (hemDX)
Enzymes [BR:
paga01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
PAGA_a0125 (hemDX)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
PAGA_a0125 (hemDX)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HemX
HEM4
DUF4366
TetR_C_13
Motif
Other DBs
NCBI-ProteinID:
ATC80734
UniProt:
A0A290RIT9
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All DBs
Position
I:111289..113121
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AA seq
610 aa
AA seq
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MTHILITRPEGKGAALAQQLEQAGYQASLFPVLKISYLTPSTTELSPLINADKIIFISQD
AVTALAQLKPTINTKAQFYAVGQQTADTIYALFGVRAAVPKLHDSEGLLALNSLAEVDGS
NIVLVKGQAGRPDIAKTLKARGAFLNNCVVYKREPISAEKTNWTDHWQSLKVQGIVITSN
AAVDAIFNNLTEQQLKWLQQCRFYVASERIAAYLQQQQVSSANIHSAAGASDTAMFSCIK
QQGSKMSEQSKPVTADNTATTKAATSAQKKEAAKAHSKPHNDKQKISKLAVLALIISLIV
ACGVGYEFYQKLNAGKAQNVAVNELKEENALLSQELQALKSAQSNLQQALFNSEQKVAAA
LNESAENNQQQLKAALQQAQQQGASLNPQEVTSLQRMAEFKLWAEKDYQGASAVLKRLDA
LLSEHPGTVAVRQAITQDIQTLDSLKPIPTEAIYLKLNSVLSNIDNLAFNAVNIPQEATE
IEKNALSEDVSDWQQNLSNSWNKLVDSFITIRQHEGVAIEPLLTDQERHLINQRIKLNVT
QAQDALMSKQASIYFSAISEAKRLVNEYFKQDDEATKVVINALTSLEKEPLNFNPEVNLQ
STQQVKEWAQ
NT seq
1833 nt
NT seq
+upstream
nt +downstream
nt
atgacacatatcctgataactcggcccgaaggaaaaggcgcagcccttgctcagcaactt
gagcaagcgggttatcaggcgtcattatttcctgttttaaaaatatcctaccttacgcct
tctactaccgagctaagcccgctaattaatgccgataaaattatttttatctctcaagat
gccgttactgcccttgcgcaattaaagccaacaataaataccaaagcgcaattttacgca
gtagggcagcaaactgcagatactatttatgcgttatttggcgtgcgcgcagcagtgcct
aaactgcatgattctgaagggttattggcgctaaactcgttagctgaggttgatggtagc
aatattgtattagtaaaaggccaagcggggcgtcctgatattgccaaaaccttaaaggcg
cgtggggcatttttaaataactgtgtggtatacaagcgcgagccaataagcgctgaaaaa
accaactggacagaccactggcaaagcctgaaagtacaaggtatagtcataaccagtaat
gcagcagttgatgcaatatttaataacctgactgaacaacagttaaagtggttacaacag
tgccgattttatgttgctagcgagcgtatagccgcttatttacaacagcaacaggtaagc
tcggctaatatacacagtgccgcaggggcaagcgataccgctatgttttcctgcataaaa
cagcaaggtagcaagatgagcgaacagtcaaagccagtaacggcagataacacagcaacc
actaaggcagcgacctcagcacaaaaaaaagaggcagctaaagcacacagtaaaccacat
aacgataagcaaaaaataagtaaattagcggtgttagcgctgatcatttcgcttattgtt
gcctgtggtgtggggtatgagttttaccaaaaactcaatgcaggtaaagcccaaaatgta
gctgttaatgaactaaaagaagaaaacgcgttattgtcacaagagttacaggcgctcaag
tctgcgcaatctaatcttcagcaagcattgttcaatagtgaacaaaaagtggctgctgcg
cttaatgaaagtgcagagaacaaccagcaacaattaaaagctgcattgcaacaagctcag
cagcaaggcgcttcactaaacccgcaagaagtaaccagcttacaacgtatggctgagttt
aaactgtgggctgaaaaagattaccaaggtgccagcgctgtacttaaacgcttagatgcc
ttattgagtgaacacccaggtactgttgcagttcgccaagcaataacacaagacattcaa
acactagatagcttaaaacctatcccaacagaagccatttacttaaaacttaatagtgtg
ttatcaaacatagataaccttgcatttaatgccgttaacataccgcaagaagcaacagaa
attgaaaaaaacgccttgagtgaagatgtaagcgattggcagcaaaacctaagtaatagc
tggaataagctagttgatagctttattactattcgccagcacgaaggggttgctatagag
ccactgctaaccgatcaggagcgccacttaattaatcaacgtattaaattaaatgtgacg
caagctcaagatgcattaatgagcaaacaagcgagcatttattttagtgccataagtgag
gcaaagcgtcttgttaatgagtactttaaacaagatgacgaggcgacaaaagtggttata
aatgcactgactagcctagaaaaagagccattaaactttaaccctgaagtaaacttacaa
agtacacagcaggttaaggagtgggcgcaatga
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