Pteropus alecto (black flying fox): 102897965
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Entry
102897965 CDS
T02993
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale04120
Ubiquitin mediated proteolysis
pale04144
Endocytosis
pale04330
Notch signaling pathway
pale04668
TNF signaling pathway
pale04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102897965 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102897965 (ITCH)
04668 TNF signaling pathway
102897965 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102897965 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102897965 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pale04131
]
102897965 (ITCH)
04121 Ubiquitin system [BR:
pale04121
]
102897965 (ITCH)
Enzymes [BR:
pale01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102897965 (ITCH)
Membrane trafficking [BR:
pale04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102897965 (ITCH)
Ubiquitin system [BR:
pale04121
]
Ubiquitin ligases (E3)
HECT type E3
102897965 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
102897965
NCBI-ProteinID:
XP_006921798
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGLELDSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVAVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLETEVVTNGETTCSESASQNDDGSRPKDETRVNTNGS
DDPEDAGPGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRMDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggattagagcttgattcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagttgcagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcactcctgtaagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagaaacaataggagacttgtcagtttgtcttgat
gggctacagttagagactgaagttgttaccaacggtgaaacgacatgttcagaaagtgct
tcacagaatgatgatggttccagacctaaggatgaaacaagagtgaacacaaatggatca
gatgaccctgaggatgcagggcctggtgaaaacaggagagtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccttctgccacttctgaaagtgat
ggatctagtacaggttctctgccgccaacaaatacaaattcaaatacatctgaaggagct
acgtctggattaataattcctcttactatatctggaggctcaggccccaggccattaaat
cctgtacctcaagctcccctaccacctggttgggagcagagaatggaccaacatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgagttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacatggcagaggccaacattggaatctgtccggaactatgaacagtggcag
ctccaacgtagtcaacttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccttgggtcccctgcca
cctggatgggagaagagaacggacagcaatggaagagtatattttgtcaaccacaacact
cgtattacacagtgggaggaccccaggagtcaaggtcagttaaatgaaaagcccttacct
gaaggttgggaaatgagattcacagtggatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccctagacaatggaccccag
atagcctatgtacgagacttcaaggcaaagtttcagtatttccggttctggtgtcagcaa
ctggccatgccacaacacataaagattacagtgacaaggaaaacattgtttgaagattct
tttcagcagataatgagcttcagtccccaagatctccgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgatttatt
ggaaggtttattgccatggctctgttccatgggaaattcatagacacaggcttttctttg
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggattg
gaaatgtacttctctgttgataaagaaattttgggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaagaatatatcagaatggta
gccgaatggaggttgtctcgaggtgttgaagaacagacgcaagctttctttgaaggcttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatctaaatgattggcaaagacatgccatttaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgtattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaaactgttatttgccattgaagaaacagaaggatttgga
caagagtga
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