Papio anubis (olive baboon): 101012351 Help Entry 101012351         CDS       T07474                                  Symbol INSR Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism panu  Papio anubis (olive baboon) Pathway panu04010   MAPK signaling pathway panu04014   Ras signaling pathway panu04015   Rap1 signaling pathway panu04022   cGMP-PKG signaling pathway panu04066   HIF-1 signaling pathway panu04068   FoxO signaling pathway panu04072   Phospholipase D signaling pathway panu04150   mTOR signaling pathway panu04151   PI3K-Akt signaling pathway panu04152   AMPK signaling pathway panu04211   Longevity regulating pathway panu04213   Longevity regulating pathway - multiple species panu04520   Adherens junction panu04910   Insulin signaling pathway panu04913   Ovarian steroidogenesis panu04923   Regulation of lipolysis in adipocytes panu04930   Type II diabetes mellitus panu04931   Insulin resistance panu04932   Non-alcoholic fatty liver disease panu04960   Aldosterone-regulated sodium reabsorption panu05010   Alzheimer disease panu05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:panu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101012351 (INSR)    04014 Ras signaling pathway     101012351 (INSR)    04015 Rap1 signaling pathway     101012351 (INSR)    04066 HIF-1 signaling pathway     101012351 (INSR)    04068 FoxO signaling pathway     101012351 (INSR)    04072 Phospholipase D signaling pathway     101012351 (INSR)    04022 cGMP-PKG signaling pathway     101012351 (INSR)    04151 PI3K-Akt signaling pathway     101012351 (INSR)    04152 AMPK signaling pathway     101012351 (INSR)    04150 mTOR signaling pathway     101012351 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     101012351 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101012351 (INSR)    04923 Regulation of lipolysis in adipocytes     101012351 (INSR)    04913 Ovarian steroidogenesis     101012351 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101012351 (INSR)   09149 Aging    04211 Longevity regulating pathway     101012351 (INSR)    04213 Longevity regulating pathway - multiple species     101012351 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     101012351 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     101012351 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101012351 (INSR)    04932 Non-alcoholic fatty liver disease     101012351 (INSR)    04931 Insulin resistance     101012351 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:panu01001]     101012351 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:panu04090]     101012351 (INSR) Enzymes [BR:panu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      101012351 (INSR) Protein kinases [BR:panu01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    101012351 (INSR) CD molecules [BR:panu04090]  Proteins   101012351 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  101012351 NCBI-ProteinID:  XP_031514923 Ensembl:  ENSPANG00000022952 LinkDB All DBs Position 20:44335278..44516260 Genome browser AA seq 1309 aa AA seqDB search MGTGGRRGTAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAARC EIHGAPRERAHMIQQDAGDASGALAMAYADIYAKGCRCAARRARDARAMRCRDARRDPPS VFPGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFE DYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNISSTSTPTSPE EHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDI VGPVTHEIFENNIVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRL RGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSIVIG SIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGS FGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVV SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAK KFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVF TTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCW QFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPENEELEMEFEDMENVPLDRSS HCQREEAGGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS NT seq 3930 nt NT seq  +upstreamnt  +downstreamnt atgggcaccgggggccggcgggggacagctgccgcgccgctgctggtggcggtggccgcg ctgctactgggcgccgcgggccacctgtaccccggagaggtgtgtcccggcatggatatc cggaacaacctcaccaggttacacgagctggagaattgctctgtcatcgaaggacacttg cagatactcttgatgttcaaaacgaggcccgaagatttccgggacctcagtttccccaaa ctcataatgatcactgattacttgctgctcttccgggtctatgggctcgagagcctgaag gacctgttccccaacctcacggtcatccggggatcacgactgttctttaactacgcgctg gtcatcttcgagatggttcacctcaaggaacttggcctctacaatctaatgaacatcacc cggggttctgtccgcatcgagaagaacaacgagctctgttacttggccactatcgactgg tcccgcatcctggattccgtggaggataattacatcgtgttgaacaaagacgacaacgag gagtgtggagacatctgtccgggtacagcgaagggcaagaccaactgccccgccactgtc atcaatgggcagtttgtcgaacggtgttggactcatagtcactgccagaaagtttgccca accatctgtaagtcacacggctgcactgccgaaggcctctgttgccacagcgagtgcctg ggcaactgttctgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg gatggcaggtgtgtggagacctgcccgcccccgtactaccacttccaggactggcgctgt gtgaacttcagcttctgccaggacctgcaccacaaatgcaagaactcacggaggcagggc tgccaccagtacgtcattcataacaacaagtgcatccctgagtgtccctccgggtacacg atgaattccagcaacttgctgtgcaccccgtgcctgggtccctgtcccaaggtatgccac ctcctagaaggcgagaagaccatcgactcggtgacgtctgcccaggagctccgaggatgc accgtcgtcaacgggagtctgatcatcaacattcgaggaggcaataatctggcagctgag ctagaagccaacctcggcctcattgaagaaatttcaggttatctaaaaatccgccgatcc tacgctctggtgtcactttccttcttccggaagttacgtctgattcgaggagagacattg gaaatcgggaactactccttctatgccttggacaaccagaacctaaggcagctctgggat tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa ctctgcttgtcagaaatccacaagatggaagaagtttcaggaaccaaggggcgccaggag agaaatgacattgccctgaagacaaatggggaccaggcatcctgtgaaaatgagttactt aaattttcttacattcggacatctttcgataagatcttgctgagatgggagccgtactgg ccccccgacttccgagacctcctggggttcatgctgttctacaaagaggctgcgcgatgc gagatccacggcgcgccgcgcgagcgcgcgcacatgatccagcaagatgctggcgatgcc agcggcgcgttagcgatggcatacgctgatatttacgcgaagggctgccgctgcgctgcg aggcgcgcgcgcgatgcgcgcgcgatgcgctgccgcgatgcgagacgcgacccgccttct gtttttccagggctgaagctgccctcgaggacctggtctccaccattcgagtctgaagat tctcagaagcacaaccagagtgaatatgaggattcagccggtgaatgttgctcctgtcca aagacagactctcagatcctgaaggagctggaggagtcctcgtttaggaagacgtttgag gattacctgcacaacgtggttttcgtccccagaaaaacctcttcaggcactggtgccgag gaccctaggccatctcggaaacgcaggtcccttggcgatgttgggaatgtgacggtggcc gtgcccacggtggcagctttccccaacatttcctcgaccagcacgcccacaagtccggag gagcacaggccctttgagaaggtggtgaacaaggagtcgctggtcatctccggcttgcga cacttcacgggctatcgcatcgagctgcaggcttgcaaccaagacacccctgaggaacgg tgcagtgtggcagcctacgtcagcgccaggaccatgcctgaagccaaggctgatgacatt gttggccctgtgacgcacgaaatctttgagaacaacatcgtccacttgatgtggcaggag ccgaaggagcccaatggcctgatcgtgctgtatgaagtgagttatcggcgatatggcgat gaggagctgcatctctgtgtgtcccgcaagcacttcgctctggaacggggctgcaggctg cgcgggctgtcgccggggaactacagcgtgcgagtccgggccacctccctcgcgggcaac ggctcctggacggagcccacctatttctacgtgacggactatttagatgtcccatcaaat attgcaaaaattatcatcggccccctcatctttgtctttctcttcagtattgtgattgga agtatttatctattcctgagaaagaggcagccagatgggcctctgggaccgctttacgct tcttcaaaccctgagtatctcagtgccagtgatgtgtttccatgctctgtgtatgtgccg gacgagtgggaggtgcctcgagagaagatcaccctccttcgagagctggggcagggctcc ttcggcatggtgtatgagggcaacgccagggacatcatcaagggtgaggcagagacccgc gtggcagtgaagacagtcaacgagtcagccagtctccgagagcggattgagttcctcaat gaggcctcggtcatgaagggcttcacctgccatcatgtggtgcgtctcctgggagtggtg tccaagggccagcccacgctggtggtgatggagctgatggctcacggagacctgaagagc tacctccgttctctgcggccagaggctgagaataatcctggccgccctccccctaccctg caagagatgattcagatggcggcggagattgctgacgggatggcctacctgaatgccaag aagttcgtgcatcgggacctggcagcgagaaactgcatggtcgcccacgattttactgtc aaaatcggagactttggaatgaccagagacatctatgaaacggattactaccggaaagga ggcaagggtctgctccctgtacggtggatggcgccggagtccctgaaggatggggtcttt accacttcttctgacatgtggtcctttggcgtggtcctttgggaaatcaccagcttggca gaacagccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatggacggaggg tatctggatcaacccgacaactgtccagagagagtcactgacctcatgcgcatgtgctgg caattcaaccccaagatgaggccaaccttcctggagatcgtcaacctgctcaaggacgac ctgcaccccagctttccggaggtgtctttctttcatagcgaggagaacaaggctcccgag aatgaggagctggagatggagtttgaggacatggagaacgtgcccctggaccgttcctcg cactgtcagagggaggaggcggggggccgggatggagggtcctcgctgggtttcaagcgg agctacgaggaacacatcccttacacccacatgaacggaggcaagaaaaacgggcggatt ctgaccttgcctcggtccaatccttcctaa

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