Papio anubis (olive baboon): 101021972
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Entry
101021972 CDS
T07474
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
panu
Papio anubis (olive baboon)
Pathway
panu00010
Glycolysis / Gluconeogenesis
panu00020
Citrate cycle (TCA cycle)
panu00620
Pyruvate metabolism
panu00785
Lipoic acid metabolism
panu01100
Metabolic pathways
panu01200
Carbon metabolism
panu01210
2-Oxocarboxylic acid metabolism
panu04066
HIF-1 signaling pathway
panu04922
Glucagon signaling pathway
panu05230
Central carbon metabolism in cancer
panu05415
Diabetic cardiomyopathy
Module
panu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
panu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101021972 (PDHA1)
00020 Citrate cycle (TCA cycle)
101021972 (PDHA1)
00620 Pyruvate metabolism
101021972 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101021972 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101021972 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101021972 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101021972 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101021972 (PDHA1)
Enzymes [BR:
panu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101021972 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF1117
Motif
Other DBs
NCBI-GeneID:
101021972
NCBI-ProteinID:
XP_031516343
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All DBs
Position
X:complement(126178412..126195101)
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AA seq
433 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLCFMRKMLAAVSRVLSGASQ
KPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG
AANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGM
DILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPI
MLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEV
RGANQWIKFKSVS
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacaccctcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtgcttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aaaccggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaa
attaagaaatgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
gaagcttgctgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcc
taccgggctcacggctttaccttcacccggggcctttccgtccgagaaattctcgcagag
cttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgcc
aagaacttctacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggatt
gctctagcctgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggt
gctgctaaccagggccagatatttgaagcttacaacatggcagctttgtggaaattacct
tgtattttcatctgtgagaataatcgctatggaatgggaacatctgttgagagagcagca
gccagcactgattactacaagagaggcgatttcattcctgggctgagagtggatggaatg
gatatcctgtgcgtccgagaggcgacaaggtttgctgctgcctattgtagatctgggaag
gggcccatcctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcct
ggagtcagttaccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatt
atgcttctcaaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaa
attgatgtggaagtgaggaaggagattgaggatgctgcccagtttgccacggccgatcct
gagccacctttggaggagctgggctaccacatctactccagcgacccacctttcgaagtt
cgtggtgccaatcagtggatcaagtttaagtcagtcagttaa
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