KEGG   PATHWAY: aacx02010
Entry
aacx02010                   Pathway                                
Name
ABC transporters - Acididesulfobacillus acetoxydans
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
aacx02010  ABC transporters
aacx02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Acididesulfobacillus acetoxydans [GN:aacx]
Gene
DEACI_1743  tungstate ABC transporter binding protein WtpA [KO:K15495]
DEACI_1744  Binding-protein-dependent transport system inner membrane component [KO:K15496]
DEACI_0596  Putative ABC transporter [KO:K15497] [EC:7.3.2.5 7.3.2.6]
DEACI_1400  SsuA/THI5-like [KO:K15553]
DEACI_1398  Binding-protein-dependent transport system inner membrane component [KO:K15554]
DEACI_1399  Putative ABC transporter [KO:K15555] [EC:7.6.2.14]
DEACI_0084  molybdate-transporting ATPase [KO:K02020]
DEACI_0594  molybdate-transporting ATPase [KO:K02020]
DEACI_0083  molybdate ABC transporter, permease protein [KO:K02018]
DEACI_0082  Putative ABC transporter [KO:K02017] [EC:7.3.2.5]
DEACI_2390  Ferric binding protein [KO:K02012]
DEACI_1020  Bacterial extracellular solute-binding protein [KO:K02012]
DEACI_2391  Binding-protein-dependent transport system inner membrane component [KO:K02011]
DEACI_1019  Binding-protein-dependent transport system inner membrane component [KO:K02011]
DEACI_2392  Putative ABC transporter [KO:K02010] [EC:7.2.2.7]
DEACI_4218  Bacterial periplasmic spermidine/putrescine-binding protein [KO:K11069]
DEACI_4222  Binding-protein-dependent transport system inner membrane component [KO:K11071]
DEACI_4219  Putative ABC transporter [KO:K11072] [EC:7.6.2.11]
DEACI_4254  Substrate binding domain of ABC-type glycine betaine transport system [KO:K02002]
DEACI_1259  Substrate binding domain of ABC-type glycine betaine transport system [KO:K02002]
DEACI_4257  Binding-protein-dependent transport system inner membrane component [KO:K02001]
DEACI_1258  Binding-protein-dependent transport system inner membrane component [KO:K02001]
DEACI_4253  glycine betaine/L-proline transport ATP binding subunit [KO:K02000] [EC:7.6.2.9]
DEACI_1257  glycine betaine/L-proline transport ATP binding subunit [KO:K02000] [EC:7.6.2.9]
DEACI_1693  Substrate binding domain of ABC-type glycine betaine transport system [KO:K05845]
DEACI_1218  Substrate binding domain of ABC-type glycine betaine transport system [KO:K05845]
DEACI_1283  Substrate binding domain of ABC-type glycine betaine transport system [KO:K05845 K05846]
DEACI_1691  Binding-protein-dependent transport system inner membrane component [KO:K05846]
DEACI_1692  Binding-protein-dependent transport system inner membrane component [KO:K05846]
DEACI_1215  Binding-protein-dependent transport system inner membrane component [KO:K05846]
DEACI_1217  Binding-protein-dependent transport system inner membrane component [KO:K05846]
DEACI_1282  Binding-protein-dependent transport system inner membrane component [KO:K05846]
DEACI_1690  glycine betaine/L-proline transport ATP binding subunit [KO:K05847] [EC:7.6.2.9]
DEACI_1216  glycine betaine/L-proline transport ATP binding subunit [KO:K05847] [EC:7.6.2.9]
DEACI_1281  glycine betaine/L-proline transport ATP binding subunit [KO:K05847] [EC:7.6.2.9]
DEACI_1745  Putative ABC transporter [KO:K10112] [EC:7.5.2.-]
DEACI_4028  Putative ABC transporter [KO:K10112] [EC:7.5.2.-]
DEACI_2143  Bacterial extracellular solute-binding protein [KO:K15770]
DEACI_3917  Bacterial extracellular solute-binding protein [KO:K15770]
DEACI_0318  Bacterial extracellular solute-binding protein [KO:K15770]
DEACI_2144  Binding-protein-dependent transport system inner membrane component [KO:K15771]
DEACI_2145  Binding-protein-dependent transport system inner membrane component [KO:K15772]
DEACI_3915  Binding-protein-dependent transport system inner membrane component [KO:K10189]
DEACI_3306  Binding-protein-dependent transport system inner membrane component [KO:K10238]
DEACI_3914  Binding-protein-dependent transport system inner membrane component [KO:K17331]
DEACI_0660  Periplasmic binding protein domain [KO:K10546]
DEACI_0662  Branched-chain amino acid transport system / permease component [KO:K10547]
DEACI_0661  Putative ABC transporter [KO:K10548] [EC:7.5.2.-]
DEACI_2154  Basic membrane protein [KO:K07335]
DEACI_2156  Branched-chain amino acid transport system / permease component [KO:K23535]
DEACI_2157  Branched-chain amino acid transport system / permease component [KO:K23536]
DEACI_2155  Putative ABC transporter [KO:K23537]
DEACI_1461  Periplasmic binding protein domain [KO:K10439]
DEACI_1466  Periplasmic binding protein domain [KO:K10439]
DEACI_1502  Periplasmic binding protein domain [KO:K10439]
DEACI_1674  Periplasmic binding protein domain [KO:K10439]
DEACI_3315  Periplasmic binding protein domain [KO:K10439]
DEACI_3723  Periplasmic binding protein domain [KO:K10439]
DEACI_1451  Periplasmic binding protein domain [KO:K10439]
DEACI_1501  Branched-chain amino acid transport system / permease component [KO:K10440]
DEACI_1672  Branched-chain amino acid transport system / permease component [KO:K10440]
DEACI_2057  Branched-chain amino acid transport system / permease component [KO:K10440]
DEACI_3312  Branched-chain amino acid transport system / permease component [KO:K10440]
DEACI_3313  Branched-chain amino acid transport system / permease component [KO:K10440]
DEACI_3724  Branched-chain amino acid transport system / permease component [KO:K10440]
DEACI_1450  Branched-chain amino acid transport system / permease component [KO:K10440]
DEACI_1449  Putative ABC transporter [KO:K10441] [EC:7.5.2.7]
DEACI_1500  Putative ABC transporter [KO:K10441] [EC:7.5.2.7]
DEACI_3314  Putative ABC transporter [KO:K10441] [EC:7.5.2.7]
DEACI_3725  Putative ABC transporter [KO:K10441] [EC:7.5.2.7]
DEACI_3726  D-ribose pyranase [rbsD] [KO:K06726] [EC:5.4.99.62]
DEACI_2058  Periplasmic binding protein domain [KO:K10537]
DEACI_2056  Putative ABC transporter [KO:K10539] [EC:7.5.2.12]
DEACI_3110  Periplasmic binding protein domain [KO:K10543]
DEACI_0659  Periplasmic binding protein domain [KO:K10543]
DEACI_3108  Branched-chain amino acid transport system / permease component [KO:K10544]
DEACI_1673  Putative ABC transporter [KO:K10545] [EC:7.5.2.10]
DEACI_3109  Putative ABC transporter [KO:K10545] [EC:7.5.2.10]
DEACI_1981  rhamnose ABC transporter, rhamnose-binding protein [KO:K10559]
DEACI_1979  Branched-chain amino acid transport system / permease component [KO:K10560]
DEACI_1980  Branched-chain amino acid transport system / permease component [KO:K10561]
DEACI_1978  Putative ABC transporter [KO:K10562] [EC:7.5.2.-]
DEACI_0178  Bacterial extracellular solute-binding protein [KO:K05813]
DEACI_1310  Bacterial extracellular solute-binding protein [KO:K05813]
DEACI_0177  Binding-protein-dependent transport system inner membrane component [KO:K05814]
DEACI_1308  Binding-protein-dependent transport system inner membrane component [KO:K05814]
DEACI_0176  Binding-protein-dependent transport system inner membrane component [KO:K05815]
DEACI_1309  Binding-protein-dependent transport system inner membrane component [KO:K05815]
DEACI_1053  ABC transporter, phosphate-binding protein PstS [KO:K02040]
DEACI_1106  Phosphate binding protein [KO:K02040]
DEACI_2459  phosphate ABC transporter, permease protein PstC [KO:K02037]
DEACI_1054  phosphate ABC transporter, permease protein PstC [KO:K02037]
DEACI_2458  Phosphate transport system permease protein PstA [KO:K02038]
DEACI_1055  Phosphate transport system permease protein PstA [KO:K02038]
DEACI_2457  phosphate-transporting ATPase [KO:K02036] [EC:7.3.2.1]
DEACI_1056  phosphate-transporting ATPase [KO:K02036] [EC:7.3.2.1]
DEACI_1620  Leu/Ile/Val-binding protein family signature [KO:K01999]
DEACI_1848  Periplasmic binding protein-like I [KO:K01999]
DEACI_0032  Periplasmic binding protein-like attachment site profile [KO:K01999]
DEACI_0435  Leu/Ile/Val-binding protein family signature [KO:K01999]
DEACI_1260  Leu/Ile/Val-binding protein family signature [KO:K01999]
DEACI_1619  Branched-chain amino acid transport system / permease component [KO:K01997]
DEACI_1847  Branched-chain amino acid transport system / permease component [KO:K01997]
DEACI_0028  Branched-chain amino acid transport system / permease component [KO:K01997]
DEACI_0434  Branched-chain amino acid transport system / permease component [KO:K01997]
DEACI_1261  Branched-chain amino acid transport system / permease component [KO:K01997]
DEACI_1618  Branched-chain amino acid transport system / permease component [KO:K01998]
DEACI_1846  Branched-chain amino acid transport system / permease component [KO:K01998]
DEACI_0027  Branched-chain amino acid transport system / permease component [KO:K01998]
DEACI_0433  Branched-chain amino acid transport system / permease component [KO:K01998]
DEACI_1262  Branched-chain amino acid transport system / permease component [KO:K01998]
DEACI_1617  Putative ABC transporter [KO:K01995]
DEACI_1845  Putative ABC transporter [KO:K01995]
DEACI_0030  Putative ABC transporter [KO:K01995]
DEACI_0432  Putative ABC transporter [KO:K01995]
DEACI_1263  Putative ABC transporter [KO:K01995]
DEACI_1616  Putative ABC transporter [KO:K01996]
DEACI_1844  Putative ABC transporter [KO:K01996]
DEACI_0029  Putative ABC transporter [KO:K01996]
DEACI_0431  Putative ABC transporter [KO:K01996]
DEACI_1264  Putative ABC transporter [KO:K01996]
DEACI_2836  Putative ABC transporter [KO:K15583]
DEACI_4190  Putative ABC transporter [KO:K15583]
DEACI_2835  Putative ABC transporter [KO:K10823]
DEACI_4192  Binding-protein-dependent transport system inner membrane component [KO:K12369]
DEACI_4191  Oligopeptide transport permease C-like, N-terminal domain protein [KO:K12370]
DEACI_1707  Solute-binding protein family 5 domain [KO:K13889]
DEACI_1708  Binding-protein-dependent transport system inner membrane component [KO:K13890]
DEACI_1709  Oligopeptide transport permease C-like, N-terminal domain protein [KO:K13891]
DEACI_2206  Hypothetical protein [KO:K02009]
DEACI_2205  Cobalamin (vitamin B12) biosynthesis protein CbiM [KO:K02007]
DEACI_4058  Cobalt uptake substrate-specific transmembrane region [KO:K02007]
DEACI_4095  Cobalt uptake substrate-specific transmembrane region [KO:K02007]
DEACI_0951  Cobalt uptake substrate-specific transmembrane region [KO:K02007]
DEACI_2207  Cobalt ECF transporter T component CbiQ [KO:K02008]
DEACI_1324  Cobalt ECF transporter T component CbiQ [KO:K02008]
DEACI_2208  Putative ABC transporter [KO:K02006]
DEACI_1008  Putative ABC transporter [KO:K02006]
DEACI_1323  Putative ABC transporter [KO:K02006]
DEACI_1009  BioY protein [KO:K03523]
DEACI_4091  ABC/ECF transporter, transmembrane component [KO:K16785]
DEACI_1007  ABC/ECF transporter, transmembrane component [KO:K16785]
DEACI_1049  ABC/ECF transporter, transmembrane component [KO:K16785]
DEACI_0199  ABC transporter integral membrane type-2 domain protein [KO:K09690]
DEACI_0715  ABC-2 family transporter protein [KO:K19341]
DEACI_0328  FtsX-like permease family [KO:K09811]
DEACI_0329  Putative ABC transporter [KO:K09812]
DEACI_0863  Putative ABC transporter [KO:K18887]
DEACI_0864  Putative ABC transporter [KO:K18888]
DEACI_2853  Putative ABC transporter [KO:K16014]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
PMID:18424520
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
PMID:18375759
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
PMID:10557362
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
PMID:11731493
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
PMID:16135226
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
PMID:11929526
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
PMID:18326572
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
PMID:16109926
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
PMID:17873039
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
PMID:17214741
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
PMID:18805970
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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