PATHWAY: babr02010 Help
Entry
Name
ABC transporters - Brucella abortus bv. 6 870
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Brucella abortus bv. 6 870 [GN:
babr ]
Gene
DO74_567 sulfate ABC transporter, sulfate-binding family protein [KO:K02048 ]
DO74_1757 sulfate ABC transporter, sulfate-binding family protein [KO:K23163 ]
DO74_568 cysT; sulfate ABC transporter, permease protein CysT [KO:K02046 ]
DO74_569 cysW; sulfate ABC transporter, permease protein CysW [KO:K02047 ]
DO74_2457 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DO74_2179 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DO74_1659 binding--dependent transport system inner membrane component family protein [KO:K15599 ]
DO74_2359 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
DO74_2913 bacterial extracellular solute-binding family protein [KO:K02012 ]
DO74_2934 bacterial extracellular solute-binding family protein [KO:K02012 ]
DO74_2914 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DO74_2935 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DO74_172 thiB; thiamin/thiamine pyrophosphate ABC transporter, thiamin/thiamine pyrophospate-binding protein [KO:K02064 ]
DO74_171 thiP; thiamine/thiamine pyrophosphate ABC transporter, permease protein [KO:K02063 ]
DO74_311 bacterial extracellular solute-binding family protein [KO:K11073 ]
DO74_315 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
DO74_313 putative spermidine/putrescine ABC transporter, permease component I protein [KO:K11075 ]
DO74_2548 bacterial extracellular solute-binding family protein [KO:K11077 ]
DO74_2547 binding--dependent transport system inner membrane component family protein [KO:K11078 ]
DO74_2546 binding--dependent transport system inner membrane component family protein [KO:K11079 ]
DO74_343 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DO74_2899 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
DO74_2898 binding--dependent transport system inner membrane component family protein [KO:K02001 ]
DO74_1645 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
DO74_1646 putative osmoprotectant uptake system permease protein yehY [KO:K05846 ]
DO74_1648 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
DO74_3104 bacterial extracellular solute-binding family protein [KO:K10117 ]
DO74_3103 binding--dependent transport system inner membrane component family protein [KO:K10118 ]
DO74_3102 binding--dependent transport system inner membrane component family protein [KO:K10119 ]
DO74_2162 bacterial extracellular solute-binding family protein [KO:K10236 ]
DO74_2161 binding--dependent transport system inner membrane component family protein [KO:K10237 ]
DO74_2160 binding--dependent transport system inner membrane component family protein [KO:K10238 ]
DO74_2710 sbpA; multiple sugar-binding periplasmic protein sbpA [KO:K10546 ]
DO74_2712 branched-chain amino acid transport system / permease component family protein [KO:K10547 ]
DO74_2434 branched-chain amino acid transport system / permease component family protein [KO:K23535 ]
DO74_3058 branched-chain amino acid transport system / permease component family protein [KO:K23535 ]
DO74_2435 branched-chain amino acid transport system / permease component family protein [KO:K23536 ]
DO74_3059 branched-chain amino acid transport system / permease component family protein [KO:K23536 ]
DO74_2942 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
DO74_2943 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
DO74_2654 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DO74_1317 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DO74_2656 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DO74_2657 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DO74_1318 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DO74_2497 xylF; D-xylose ABC transporter, D-xylose-binding protein [KO:K10543 ]
DO74_2198 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10543 ]
DO74_2495 branched-chain amino acid transport system / permease component family protein [KO:K10544 ]
DO74_2196 branched-chain amino acid transport system / permease component family protein [KO:K10544 ]
DO74_2786 periplasmic binding s and sugar binding domain of LacI family protein [KO:K17202 ]
DO74_2785 branched-chain amino acid transport system / permease component family protein [KO:K17203 ]
DO74_290 periplasmic binding s and sugar binding domain of LacI family protein [KO:K17205 ]
DO74_289 branched-chain amino acid transport system / permease component family protein [KO:K17206 ]
DO74_2973 bacterial extracellular solute-binding family protein [KO:K05813 ]
DO74_2972 binding--dependent transport system inner membrane component family protein [KO:K05814 ]
DO74_2971 binding--dependent transport system inner membrane component family protein [KO:K05815 ]
DO74_1905 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
DO74_1904 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
DO74_2699 bacterial extracellular solute-binding s, 3 family protein [KO:K09969 ]
DO74_1128 bacterial extracellular solute-binding s, 3 family protein [KO:K09969 ]
DO74_1127 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K09970 ]
DO74_1124 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K09971 ]
DO74_2951 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
DO74_2950 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
DO74_146 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DO74_2691 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DO74_2472 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DO74_2417 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DO74_2451 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DO74_2099 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DO74_2979 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DO74_2471 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DO74_2098 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DO74_147 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DO74_2690 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DO74_2978 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DO74_2416 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DO74_2450 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DO74_2686 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
DO74_3085 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15580 ]
DO74_3086 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15580 ]
DO74_3087 binding--dependent transport system inner membrane component family protein [KO:K15581 ]
DO74_3088 binding--dependent transport system inner membrane component family protein [KO:K15582 ]
DO74_336 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
DO74_337 binding--dependent transport system inner membrane component family protein [KO:K12369 ]
DO74_338 binding--dependent transport system inner membrane component family protein [KO:K12370 ]
DO74_2836 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15584 ]
DO74_2837 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15584 ]
DO74_1850 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
DO74_1851 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
DO74_1852 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
DO74_1853 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
DO74_536 cobalt uptake substrate-specific transmembrane region family protein [KO:K02007 ]
DO74_534 cbiQ; cobalt ABC transporter, permease protein CbiQ [KO:K02008 ]
DO74_1051 liporeleasing system, transmembrane , LolC/E family protein [KO:K09808 ]
DO74_420 ABC transporter transmembrane region 2 family protein [KO:K02471 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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