KEGG   PATHWAY: bmab00630
Entry
bmab00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia mallei 2002734299
Class
Metabolism; Carbohydrate metabolism
Pathway map
bmab00630  Glyoxylate and dicarboxylate metabolism
bmab00630

Module
bmab_M00012  Glyoxylate cycle [PATH:bmab00630]
bmab_M00621  Glycine cleavage system [PATH:bmab00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia mallei 2002734299 [GN:bmab]
Gene
BM45_1331  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BM45_1999  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BM45_4724  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BM45_1327  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BM45_4101  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BM45_4094  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BM45_4105  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BM45_229  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BM45_55  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BM45_1468  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BM45_1576  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BM45_1581  acetyl-CoA C-acyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BM45_1577  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BM45_2581  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
BM45_2580  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
BM45_2579  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
BM45_3376  catalase family protein [KO:K03781] [EC:1.11.1.6]
BM45_941  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BM45_4852  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BM45_1071  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BM45_1192  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BM45_837  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
BM45_4791  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
BM45_2912  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BM45_2910  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
BM45_4524  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BM45_1213  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BM45_1650  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BM45_2911  gcvH; glycine cleavage system H protein [KO:K02437]
BM45_1441  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BM45_4425  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BM45_2606  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BM45_3343  bicupin, oxalate decarboxylase family protein [KO:K01569] [EC:4.1.1.2]
BM45_2375  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BM45_4037  Tat (twin-arginine translocation) pathway signal sequence domain protein [KO:K00123] [EC:1.17.1.9]
BM45_2374  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
BM45_4034  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
BM45_2373  thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]
BM45_4033  formate dehydrogenase, gamma subunit [KO:K00127]
BM45_1958  alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]
BM45_670  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BM45_2894  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BM45_4802  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BM45_1069  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bmab00010  Glycolysis / Gluconeogenesis
bmab00020  Citrate cycle (TCA cycle)
bmab00030  Pentose phosphate pathway
bmab00053  Ascorbate and aldarate metabolism
bmab00071  Fatty acid degradation
bmab00230  Purine metabolism
bmab00250  Alanine, aspartate and glutamate metabolism
bmab00260  Glycine, serine and threonine metabolism
bmab00620  Pyruvate metabolism
bmab00710  Carbon fixation by Calvin cycle
bmab00750  Vitamin B6 metabolism
bmab00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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